Check out our lab's latest preprint investigating RNA polymerase backtracking and type III CRISPR-Cas immunity: www.biorxiv.org/content/10.6... Special shoutout to @angeljhv.bsky.social for leading this work!
RNA Polymerase Backtracking Promotes Type III-A CRISPR DNA Targeting
Type III CRISPR-Cas systems provide transcription-dependent immunity against mobile genetic elements, yet the mechanism underlying their DNA targeting remains unclear. Although the type III effector C...
biorxiv.org