Desynchronization of intestinal circadian clocks and gastrointestinal dysfunction

Nature Reviews Gastroenterology & Hepatology, Published online: 29 July 2026; doi:10.1038/s41575-026-01241-5Intestinal circadian clocks are emerging as important regulators of gastrointestinal physiology and homeostasis. Recent advances suggest that desynchronization of circadian clocks in distinct intestinal cell types could contribute to gastrointestinal dysfunction, highlighting new opportunities to understand disease mechanisms and identify future research priorities.

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Multidisciplinary Delphi consensus statement on minimal standards for clinical metadata and end points in microbiome studies

Nature Reviews Gastroenterology & Hepatology, Published online: 03 August 2026; doi:10.1038/s41575-026-01229-1In this Consensus Statement, an international panel of experts provides recommendations to harmonize metadata, sampling, analysis and end points in gut microbiome-based clinical research.

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Multidisciplinary Delphi consensus statement on minimal standards for clinical metadata and end points in microbiome studies

Nature Reviews Gastroenterology & Hepatology, Published online: 03 August 2026; doi:10.1038/s41575-026-01229-1In this Consensus Statement, an international panel of experts provides recommendations to harmonize metadata, sampling, analysis and end points in gut microbiome-based clinical research.

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Mechanisms, management and prevention of anorectal sexually transmitted infections

Nature Reviews Gastroenterology & Hepatology, Published online: 31 July 2026; doi:10.1038/s41575-026-01232-6Anorectal bacterial sexually transmitted infections (STIs) remain a global health challenge. This Review provides an overview of anorectal bacterial STIs focusing on chlamydia, gonorrhoea and syphilis, with insights into global burden, pathophysiology, management and prevention, as well as highlighting knowledge gaps and research priorities.

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Mechanisms, management and prevention of anorectal sexually transmitted infections

Nature Reviews Gastroenterology & Hepatology, Published online: 31 July 2026; doi:10.1038/s41575-026-01232-6Anorectal bacterial sexually transmitted infections (STIs) remain a global health challenge. This Review provides an overview of anorectal bacterial STIs focusing on chlamydia, gonorrhoea and syphilis, with insights into global burden, pathophysiology, management and prevention, as well as highlighting knowledge gaps and research priorities.

dlvr.it

Desynchronization of intestinal circadian clocks and gastrointestinal dysfunction

Nature Reviews Gastroenterology & Hepatology, Published online: 29 July 2026; doi:10.1038/s41575-026-01241-5Intestinal circadian clocks are emerging as important regulators of gastrointestinal physiology and homeostasis. Recent advances suggest that desynchronization of circadian clocks in distinct intestinal cell types could contribute to gastrointestinal dysfunction, highlighting new opportunities to understand disease mechanisms and identify future research priorities.

dlvr.it

Desynchronization of intestinal circadian clocks and gastrointestinal dysfunction

Nature Reviews Gastroenterology & Hepatology, Published online: 29 July 2026; doi:10.1038/s41575-026-01241-5Intestinal circadian clocks are emerging as important regulators of gastrointestinal physiology and homeostasis. Recent advances suggest that desynchronization of circadian clocks in distinct intestinal cell types could contribute to gastrointestinal dysfunction, highlighting new opportunities to understand disease mechanisms and identify future research priorities.

dlvr.it

Understanding intrapancreatic fat: charting a path forward

Nature Reviews Gastroenterology & Hepatology, Published online: 20 July 2026; doi:10.1038/s41575-026-01234-4Two independent Delphi-driven consensus initiatives have established the first standardized frameworks for defining, measuring and managing intrapancreatic fat. Their areas of agreement provide a foundation for clinical recognition, while key divergences in terminology, thresholds and evidence appraisal highlight critical questions that must be resolved through rigorous collaborative research.

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Dupilumab shows promise in eosinophilic gastritis

Nature Reviews Gastroenterology & Hepatology, Published online: 17 July 2026; doi:10.1038/s41575-026-01239-zDupilumab shows promise in eosinophilic gastritis

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PIEZO1 senses the mechanics of liver regeneration

Nature Reviews Gastroenterology & Hepatology, Published online: 16 July 2026; doi:10.1038/s41575-026-01237-1PIEZO1 senses the mechanics of liver regeneration

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Conceptual framework and expert guidance on intrapancreatic fat deposition: the Melbourne consensus

Nature Reviews Gastroenterology & Hepatology, Published online: 16 July 2026; doi:10.1038/s41575-026-01224-6In this Consensus Statement, a global multidisciplinary group of experts provide a structured framework and clear guidance on intrapancreatic fat deposition and fatty pancreas disorder.

dlvr.it

Steatosis fuels replacement liver metastases in colorectal cancer

Nature Reviews Gastroenterology & Hepatology, Published online: 16 July 2026; doi:10.1038/s41575-026-01236-2Steatosis fuels replacement liver metastases in colorectal cancer

dlvr.it

Understanding intrapancreatic fat: charting a path forward

Nature Reviews Gastroenterology & Hepatology, Published online: 20 July 2026; doi:10.1038/s41575-026-01234-4Two independent Delphi-driven consensus initiatives have established the first standardized frameworks for defining, measuring and managing intrapancreatic fat. Their areas of agreement provide a foundation for clinical recognition, while key divergences in terminology, thresholds and evidence appraisal highlight critical questions that must be resolved through rigorous collaborative research.

dlvr.it

Understanding intrapancreatic fat: charting a path forward

Nature Reviews Gastroenterology & Hepatology, Published online: 20 July 2026; doi:10.1038/s41575-026-01234-4Two independent Delphi-driven consensus initiatives have established the first standardized frameworks for defining, measuring and managing intrapancreatic fat. Their areas of agreement provide a foundation for clinical recognition, while key divergences in terminology, thresholds and evidence appraisal highlight critical questions that must be resolved through rigorous collaborative research.

dlvr.it

Mechanisms and clinical outcomes linking HLA-DRB1*01:03 and IBD

Nature Reviews Gastroenterology & Hepatology, Published online: 13 July 2026; doi:10.1038/s41575-026-01233-5Mechanisms and clinical outcomes linking HLA-DRB1*01:03 and IBD

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Features of immune microenvironment associated with colorectal polyp development

Nature Reviews Gastroenterology & Hepatology, Published online: 13 July 2026; doi:10.1038/s41575-026-01230-8Features of immune microenvironment associated with colorectal polyp development

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Dupilumab shows promise in eosinophilic gastritis

Nature Reviews Gastroenterology & Hepatology, Published online: 17 July 2026; doi:10.1038/s41575-026-01239-zDupilumab shows promise in eosinophilic gastritis

dlvr.it

Precision adherence support for hepatitis C treatment

Nature Reviews Gastroenterology & Hepatology, Published online: 17 July 2026; doi:10.1038/s41575-026-01238-0Precision adherence support for hepatitis C treatment

dlvr.it

PIEZO1 senses the mechanics of liver regeneration

Nature Reviews Gastroenterology & Hepatology, Published online: 16 July 2026; doi:10.1038/s41575-026-01237-1PIEZO1 senses the mechanics of liver regeneration

dlvr.it

Steatosis fuels replacement liver metastases in colorectal cancer

Nature Reviews Gastroenterology & Hepatology, Published online: 16 July 2026; doi:10.1038/s41575-026-01236-2Steatosis fuels replacement liver metastases in colorectal cancer

dlvr.it

Conceptual framework and expert guidance on intrapancreatic fat deposition: the Melbourne consensus

Nature Reviews Gastroenterology & Hepatology, Published online: 16 July 2026; doi:10.1038/s41575-026-01224-6In this Consensus Statement, a global multidisciplinary group of experts provide a structured framework and clear guidance on intrapancreatic fat deposition and fatty pancreas disorder.

dlvr.it

Dupilumab shows promise in eosinophilic gastritis

Nature Reviews Gastroenterology & Hepatology, Published online: 17 July 2026; doi:10.1038/s41575-026-01239-zDupilumab shows promise in eosinophilic gastritis

dlvr.it

Precision adherence support for hepatitis C treatment

Nature Reviews Gastroenterology & Hepatology, Published online: 17 July 2026; doi:10.1038/s41575-026-01238-0Precision adherence support for hepatitis C treatment

dlvr.it

PIEZO1 senses the mechanics of liver regeneration

Nature Reviews Gastroenterology & Hepatology, Published online: 16 July 2026; doi:10.1038/s41575-026-01237-1PIEZO1 senses the mechanics of liver regeneration

dlvr.it

EASL Congress 2026

Nature Reviews Gastroenterology & Hepatology, Published online: 10 July 2026; doi:10.1038/s41575-026-01231-7EASL Congress 2026

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Steatosis fuels replacement liver metastases in colorectal cancer

Nature Reviews Gastroenterology & Hepatology, Published online: 16 July 2026; doi:10.1038/s41575-026-01236-2Steatosis fuels replacement liver metastases in colorectal cancer

dlvr.it

Conceptual framework and expert guidance on intrapancreatic fat deposition: the Melbourne consensus

Nature Reviews Gastroenterology & Hepatology, Published online: 16 July 2026; doi:10.1038/s41575-026-01224-6In this Consensus Statement, a global multidisciplinary group of experts provide a structured framework and clear guidance on intrapancreatic fat deposition and fatty pancreas disorder.

dlvr.it