The 63rd annual @lasa-uk.bsky.social meeting will focus on disease modelling and the care of research animals. 📅 Mon 16 – Wed 18 November 👉 nc3rs.org.uk/events/lasa-... LASA strongly encourage the participation of early career animal technologists and researchers, including post-graduate students.

Biostatistician Penny Reynolds and NC3Rs Programme Manager @drejpearl.bsky.social discuss transparent reporting of animal research in the 60th anniversary edition of the Laboratory Animals Journal, exploring the link between the 3Rs, scientific quality and animal welfare: doi.org/10.1177/0023...

Reporting and transparency in laboratory animal science: Past achievements, present concerns and future directions - Penny S. Reynolds, Esther J. Pearl, 2026

Transparent reporting of animal research is both a scientific and ethical imperative and is linked to both research quality and the principles of Replacement, R...

doi.org

Two new in silico models developed through the NC3Rs Thyroid Tox CRACK IT Challenge are able to predict thyroid receptor-mediated endocrine disruption and offer an alternative to some animal studies for thyroid endpoints. Find out more and access the models: nc3rs.org.uk/crackit/thyr...

Today we are pleased to launch the DRIVER recommendations, a new framework designed to improve the quality, reliability and reproducibility of research using in vitro models: nc3rs.org.uk/news/driver-...

The DRIVER recommendations: Improving the quality of in vitro research

New NC3Rs recommendations set international standards for designing and reporting in vitro research.

nc3rs.org.uk

Three months on from launching SIRF-UP, an @eu-sabv.bsky.social initiative to support ethical review bodies assess sex inclusivity in animal research, a new publication renews our call to get involved, share your experiences and use the Sex Inclusive Research Framework. 👉 doi.org/10.1177/0023...

Recordings available – Best practice in research animal anaesthesia: nc3rs.org.uk/3rs-resource... Veterinary anaesthetists from the Research Animal Anaesthesia Network (RAAN) shared their expertise and advice with over 300 attendees from 26 countries, to improve welfare and experimental outcomes.

Register now for the sixth webinar in our Technology Partn3Ring series on new approach methodologies (NAMs) to explore collaboration opportunities with the speakers. Wednesday 15 July 14.00 – 15.15 BST Register 👉 events.teams.microsoft.com/event/ed2a34...

The fifth annual Galleria mellonella workshop returns with a two-day programme including a research seminar and hands-on laboratory sessions. Organised by @gmrc.bsky.social to support the use of Galleria as a partial replacement model. 📅 8 – 9 September 📍 Exeter, UK 👉 nc3rs.org.uk/events/galle...

💬 Share your thoughts on where alternatives to replace animal use would have the most significant impact: engagementhub.ukri.org/mrc-peg/expr... 🥼 For scientists in academia and industry. ⏰ <15 minutes to complete. 📅 Deadline: 7 August. With @ukri.org MRC, BBSRC, EPSRC and @innovateuk.bsky.social.

3Rs leaflets are available to engage public audiences about efforts to replace, reduce and refine animal use in research: nc3rs.org.uk/3rs-resource... Created by Dr Yu Liu @mrc-lms.bsky.social with the support of the NC3Rs Communications Team and funding through our public engagement award scheme.

NAMs Technology Partn3Ring webinar: Session 5 17 June, 14.00 BST Explore in silico modelling, bioengineered bone organoids, airway-on-chip, and human cardiac tissue models for preclinical drug development and toxicity assessment. Register 👉 events.teams.microsoft.com/event/7b230e...

Register now for two upcoming sessions on best practice in research animal anaesthesia to improve welfare and experimental outcomes. 📅 16 and 25 June, 12.00 – 13.00 🙋🏻‍ For researchers, animal technicians and veterinarians 📜 Certificates of attendance available 👉 nc3rs.org.uk/welfare-webi...

Over 100 people joined our @pintofscience.uk events in Newcastle, Bristol and London last week to meet NC3Rs-funded scientists pioneering new approaches to replace animal use to study disease and develop medicines – including human tissue, organoids, organ-on-chip, 3D bioprinting and fruit flies.

Please note that our websites (including the main NC3Rs site, Innovation Platform and ARRIVE guidelines site) may be down for maintenance this evening (UK time) for up to an hour. We apologise for any inconvenience caused. This post will be updated once the work has been carried out.

We are supporting technical staff at Newcastle University to drive the uptake of refined mouse pick up methods across the UK. Discover how their workshops have supported staff at the University of Leeds to implement cup and tunnel handling as standard. Read the blog: nc3rs.org.uk/news/making-...

Making refined mouse handling the UK standard

The NC3Rs is supporting technical staff at Newcastle University to drive the uptake of refined mouse pick up methods across UK institutions.

nc3rs.org.uk

Are you interested in learning more about science happening in your city to study disease, find new drugs and improve human health without using animals? Meet scientists replacing animals in research at NC3Rs @pintofscience.uk events next week! 🎟️ Buy your ticket: pintofscience.co.uk/sponsor/nc3rs/

Our Experimental Design Assistant (EDA) can be used as a tool to teach others about key experimental design concepts in an interactive way. Join our online train-the-trainers workshop with @irise-eu.bsky.social to find out more. 📅 10 and 17 June, 13.00 – 16.00 BST 👉 nc3rs.org.uk/events/irise...

The countdown is on! The deadline for applications to our international 3Rs Prize, sponsored by GSK, is fast approaching. Submit your publication for consideration by Monday 4 May 2026: nc3rs.org.uk/internationa...

NC3Rs@nc3rs.bsky.social · 4mo ago

We invite researchers from around the world to showcase their 3Rs achievements on the global stage by applying for our annual NC3Rs 3Rs Prize: nc3rs.org.uk/internationa...

We invite researchers from around the world to showcase their 3Rs achievements on the global stage by applying for our annual NC3Rs 3Rs Prize: nc3rs.org.uk/internationa...

International 3Rs Prize

nc3rs.org.uk

We are thrilled to be returning to @pintofscience.uk for our twelfth year as festival sponsors! Join us in Newcastle, Bristol and London as NC3Rs-funded scientists showcase innovations in replacement approaches and explore the future of alternatives to animals. 🎟️ pintofscience.co.uk/sponsor/nc3rs/

SIRF-UP is an @eu-sabv.bsky.social COST Action initiative to support ethical review bodies assess sex-inclusivity in animal research. Using female and male animals should be the default to reduce the total number of animals used and produce results that are generalisable to the whole population.

Webinar recording available: nc3rs.org.uk/3rs-resource... Myomaker Bio share an in vitro vascularised and innervated skeletal muscle model developed through the NC3Rs STRATIS CRACK IT Challenge to improve translation in musculoskeletal research and replace some animals in preclinical drug screening.

Are you interested in collaborating on the latest replacement technologies for chemical or drug testing? Register for the first two sessions in our upcoming Technology Partn3Ring webinar series on new approach methodologies: nc3rs.org.uk/crackit/nams... 📅 22 April and 6 May, 14.00 – 15.15 (BST)

We have awarded over £200k across nine teams through a new joint funding initiative with the BBSRC: nc3rs.org.uk/news/bridgin... Our Business Interaction Voucher awards support cross-sector collaborations to enhance the biological relevance of 3Rs models and ensure they are fit for use in industry.

Bridging the gap: New funding for academic-industry partnerships between NC3Rs Network members

In partnership with the BBSRC we have awarded over £200k to strengthen cross-sector collaborations that improve the relevance and real-world impact of 3Rs models and technologies.

nc3rs.org.uk

To celebrate British Science Week, NC3Rs staff took part in eight @imascientist.org.uk online chats last week, meeting around 150 school students. It is always great to see how curious young people are about the ways that scientists are replacing, reducing and refining the use of animals!

⏳ Applications close this Friday, 6 March. If you are interested in becoming an Antibody Champion, complete the short (~10 minute) online application today to tell us why you would make a great champion and your current experiences of working with antibodies and promoting best scientific practice.

NC3Rs@nc3rs.bsky.social · 6mo ago

We are working with @oga-community.bsky.social to recruit a cohort of early career researchers who will drive the validation and use of better antibodies. Are you our next Antibody Champion? More details, eligibility and application process: nc3rs.org.uk/news/antibod...

Register for upcoming 3Rs events from the NC3Rs and others taking place online this week: nc3rs.org.uk/events ⬇️ Details in the thread below.

Register for our next virtual workshop on using the Experimental Design Assistant (EDA): nc3rs.org.uk/events/exper... 📅 Wednesday 4 March, 16.00 – 18.00 (GMT) ⏰ Registration closes: Tuesday 3 March 📜 Certificates of attendance available for one CPD point

To support delivery of the UK Government’s alternatives strategy, we are working with @innovateuk.bsky.social on a Contracts for Innovation competition, with £2M available for non-animal approaches in pharmacokinetic prediction and cardiovascular safety. Learn more: nc3rs.org.uk/news/working...

📢 Webinar – Human in vitro tissue models of musculoskeletal disease and injury: nc3rs.org.uk/events/human... 📅 Thursday 5 March, 14.00 (GMT) Learn more about an in vitro vascularised and innervated skeletal muscle model of traumatic injury, developed through our STRATIS CRACK IT Challenge.