Published in Nature Protocols, this new tutorial from NIH researchers provides a practical roadmap for integrating frontier large language models (LLMs) into healthcare. www.nature.com/articles/s41...

Tutorial: guidance on the use of large language models for medical research - Nature Protocols

An entry-level guide for understanding how to choose large language models for medical research applications, customize the prompts and fine-tune the models’ performance.

nature.com

Register now for the upcoming NCI Office of Data Sharing Seminar Series on July 29, 2026! Join Dr. Julian Hong of UCSF as he presents "Generalizable Multimodal AI Approaches to Advance Cancer Care Delivery." Register here: events.cancer.gov/ods/webinar/...

📢 Registration deadline extended! Join the 2026 #NCIDataJamboree (Nov. 16–18) using public cancer datasets to advance cancer research. Submit your project and register by July 27, 2026. events.cancer.gov/nci/datajamb...

The latest development in lymphoma research took center stage at the AACR Special Conference on Advances in Malignant Lymphoma. Explore highlights from the meeting on the #AACRBlog: www.aacr.org/blog/2026/07... #AACRlymphoma26

Congratulations to Dr. Haval Shirwan on being named the recipient of the 2026 Basic Science Established Investigator Award by the American Society of Transplantation (AST)! www.myast.org/blog/ast-con...

AST Congratulates 2026 Award Recipients

Make a difference in the field of transplantation by donating to support our cause.

myast.org

What if bacteria could be programmed to find tumors and deliver cancer therapies directly where they're needed? A new Nature Cancer Perspective by Noah Chen, Zaofeng Yang, and Nicholas Arpaia explores the promise of engineered bacteria as living therapeutics: rdcu.be/fmtyo

Bacterial engineering for cancer therapy

Nature Cancer - In this Perspective, Arpaia and colleagues provide an overview of bacteria-based cancer therapies, discussing the potential of engineered bacteria as living drug delivery systems as...

rdcu.be

Join the NCI Division of Cancer Prevention Immunology Interest Group for a special seminar presentation on Wednesday June 10 at 1pm ET. We will hear from Dr. Nicholas Arpaia: "Programmable Probiotics for Personalized Cancer Immunoprevention and Immunotherapy." Register today: go.nih.gov/QysclHR

Register now for the NCI Division of Cancer Prevention Early Career Scientist Spotlight Research Seminar Series. events.cancer.gov/dcp/early-ca...

A curated list of NIH/NCI shared resources is now available on our web portal. Check it out: nci-cipnet.org/en/resources...

Great kickoff for the CIP-Net Resource Sharing WG today! 🚀 Many thanks to WG Chairs Drs. Anjana Bhardwaj/Henry Withers for leading a thoughtful discussion on building a collaborative framework for resource sharing .And thank you to all members for the active participation & valuable input.

🥦 New #CIPNetPublication highlights the power of diet in cancer interception pubmed.ncbi.nlm.nih.gov/41342739/ #CancerPrevention #Immunoprevention #Microbiome #MultipleMyeloma

At today’s #CIPNetSCMeeting, Dr. Haval Shirwan delivered opening remarks, followed by a network update from Dr. Alan Hutson. Dr. Sean Hanlon of NCI presented on #HTAN. Dr. Tal Danino shared a progress report on engineered probiotic bacteria for colorectal cancer #immunoprevention and interception.

CIP-Net Project Spotlight: Developing a novel CD137 agonist (SA-4-1BBL) to train the immune system for cancer #immunoprevention. Led by Haval Shirwan & Esma Yolcu, this project explores how immune activation can prevent tumor development in high-risk populations. www.nci-cipnet.org/en/members/u...

Apply to access the scientific capabilities and resources of the National Cancer Institute (NCI) with the goal of moving promising cancer preventive agents into clinical testing. prevention.cancer.gov/research-are...

The Cancer Immunoprevention Network, established by the National Cancer Institute, advances the understanding of fundamental immunoprevention mechanisms, drives the discovery of novel strategies, and supports the preclinical development and testing of new interventions. More info: nci-cipnet.org

Join us today at 11 AM ET for the Early Career Scientist Spotlight Research Seminar Series, hosted by the NCI Division of Cancer Prevention. events.cancer.gov/dcp/early-ca...

🧬 CIP-Net Project Spotlight: What drives the transition from MGUS to multiple myeloma? This project led by Drs. Madhav Dhodapkar, Richard Flavell, & Noah Palm explores how gut microbes may act as antigenic triggers for B cells. nci-cipnet.org/en/members/u...

Register now for the NCI Division of Cancer Prevention Early Career Scientist Spotlight Research Seminar Series. events.cancer.gov/dcp/early-ca...

Register now for the @theNCI Division of Cancer Prevention Early Career Scientist Spotlight Research Seminar Series. events.cancer.gov/dcp/early-ca...

🧬CIP-Net Project Spotlight: Led by Drs. Peter Leif Bergsagel and Marta Chesi of Mayo Clinic, this project investigates how inflammatory cues within the bone marrow microenvironment promote malignant progression during SMM. Learn more👉https://nci-cipnet.org/en/members/ug3ca290468/

Only a few spots remaining! This is a great opportunity for early stage investigators to showcase their work to a broad scientific community. prevention.cancer.gov/funding-and-...

At today’s #CIPNetSCMeeting, Dr. Haval Shirwan and Dr. Preethi Gunaratne announced the formation of a White Paper Task Force and invited additional interested participants to join. Dr. Alan Hutson shared DRCC updates. Drs. Leif Bergsagel and Marta Chesi presented progress on their UG3 project.

🧬CIP-Net Project Spotlight: Immune determinants modulating cancer development in #LynchSyndrome This project will define the shared frameshift neoantigens and T cell features that restrain progression from precancerous polyps to CRC. 👉https://nci-cipnet.org/en/members/ug3ca290517/

🧬 CIP-Net Project Spotlight - Investigating novel targets for topical immunoprevention of keratinocytic skin cancer. Led by Drs. Sally Dickinson and Curiel Clara, this project explores how UV-induced immune checkpoint signals drive early skin carcinogenesis. www.nci-cipnet.org/en/members/u...

New #CIPNetPublication: Drs. Haval Shirwan, Esma Yolcu and team dissect how SA-4-1BBL, a CD137 agonist, drives balanced and durable immune activation to prevent cancer, using advanced bioinformatics and transcriptomic analyses. The work is published in Biomolecules MDPI www.mdpi.com/2218-273X/16...

🧬CIP-Net Project Spotlight UG3CA290300, led by Dr. Shadmehr Demehri, is investigating how the immune system can protect normal breast tissue and intercept cancer before it starts in people with inherited BRCA mutations 👉Learn more: www.nci-cipnet.org/en/members/u...

🧬 CIP-Net Project Spotlight UG3CA290454 is developing a preventive cancer vaccine for people with inherited BRCA1/2 mutations, using chimeric RNA-derived neoantigens to stop breast cancer before it forms. 👉Learn more on the CIP-Net website: www.nci-cipnet.org/en/members/u...

At today’s NCI Computational Oncology Working Group meeting, Dr. Roland Dunbrack of Fox Chase Cancer Center presented his work on structural bioinformatics and AlphaFold modeling of the human kinome and its interactions.

#CIPNetPublication in Nature Cancer by Dr. Madhav Dhodapkar: The MyCheckpoint randomized trial reports durable clinical responses in multiple myeloma following TIGIT or LAG3 immune checkpoint blockade, with distinct pathway-specific immune correlates for each arm. pubmed.ncbi.nlm.nih.gov/39187595/

Clinical response and pathway-specific correlates following TIGIT-LAG3 blockade in myeloma: the MyCheckpoint randomized clinical trial - PubMed

Persons with myeloma were randomized to receive an anti-TIGIT (T cell immunoreceptor) or anti-LAG3 (lymphocyte activation gene) antibody followed by combination with pomalidomide and dexamethasone ( NCT04150965 ). Primary and secondary endpoints were safety and efficacy, respectively. Therapy was we …

pubmed.ncbi.nlm.nih.gov