Excited to share new work from the lab led by Laura Sichlinger and published in Science Advances - thank you to all involved! Please see the new article below for more information and links to the paper!

Institute of Psychiatry, Psychology & Neuroscience@kingsioppn.bsky.social · 3mo ago

New research from Professor Deepak Srivastava, Professor Anthony Vernon and Dr Laura Sichlinger uncovers what #schizophrenia risk gene ZNF804A is doing as neurons develop. @ncndgroup.bsky.social

Brain #organoids have huge potential for 💊 testing drugs, 🧬 researching genetics and 🧠 studying brain development. New research from @ncndgroup.bsky.social @adampavlinek.bsky.social scales up experiments and reduces variability. 🔗 www.kcl.ac.uk/news/a-long-...

A long-term and scalable system to record from neural organoids | King's College London

A new brain organoid system helps reduce unwanted variability and scales up experiments for higher throughput drug testing and genetic research.

kcl.ac.uk

We are recruiting for a Research Associate / Project Manager to help us build and run a Brain Organoid Platform at King’s College London, as part of the UK Human Functional Genomics Neurodevelopment Cluster! www.kcl.ac.uk/jobs/125125-...

Research Associate - Project Manager - Brain Organoid Platform | King's College London

kcl.ac.uk

Excited to share our newest preprint, Electrophysiological development and functional plasticity in dissociated human cerebral #organoids across multiple cell lines 🧠🔬🧪: doi.org/10.1101/2025... This is based on some of the work I did in my PhD with the great @ncndgroup.bsky.social 1/5

🚨happy to share a new pre-print from the lab - lead author Adam has characterised a scaleable model to study electrophysiological properties in cultures derived from neural organoids! 👇🏾

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last yr.

Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines https://www.biorxiv.org/content/10.1101/2025.03.24.644896v1

🚨 new pre-print from the group - this work led by Despoina Goniotaki looks at the influence of abnormal tau species on endo-lysosome function using proteomics and live cell resolution imaging approaches! 👇🏾

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last yr.

Proteomic Analysis Links Truncated Tau to Lysosome Motility, Autophagy and Endo-lysosomal Dysfunction https://www.biorxiv.org/content/10.1101/2025.03.18.643906v1

We posted this pre-print a while ago - but wanted to post it here now! Huge amount of by Laura the lead author - love to hear any feedback!

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 3y ago

Schizophrenia risk gene ZNF804A controls ribosome localization and synaptogenesis in developing human neurons https://www.biorxiv.org/content/10.1101/2024.02.02.578424v1

Thinking of leaving the other place - looking for signs of life here!