The Lab of Stephan Grill at MPI-CBG has finally made it to Bluesky and we also have a brand new homepage: grill-lab.org Check it out.
Jonas Neipel
@neipel.bsky.social
Theoretical biophysicists in Grill and Jülicher labs. (MPI-CBG, MPI-PKS Dresden) Interested in anything from genome regulation to developmental biology, currently focusing on left-right symmetry breaking and shape/curvature/ geometry sensing.
(4/10) We quantified these chiral tissue flows in 25 quail embryos and inferred forces using a fluid model, suggesting a torque of 6μNμm is generated locally at the node.
(1/10) I am excited to finally share our work on avian left/right symmetry breaking with you. We reveal a tissue-scale active torque dipole generated at the Hensen’s node, thanks to crazy experiments by Julia @juliapfanzelter.bsky.social and some analysis by me. doi.org/10.1101/2025...
An active torque dipole across tissue layers drives avian left-right symmetry breaking
Unlike in mice, frogs, and fish, left-right (L/R) body axis formation in avian embryos does not arise from the chiral beat of cilia. Instead, a counter-clockwise tissue rotation around Hensen′ node, t...
doi.org