Proud to share this elegant work by the very talented Dr. Edward Song on the engineered overexpression of CXCR3 in #CARTcells to drive better trafficking to pediatric brain & spinal tumors (beautiful art by www.katierisvicari.com) #VitanzaLab @seattlechildrens.org www.nature.com/articles/s41...
Nick Vitanza
@nickvitanza.bsky.social
Scientific Director of Seattle Children's Brain Tumor Research Program Neuro-oncologist & Scientist focused on biologic vulnerabilities of #DIPG & #CARTcell #immunotherapy
Honored to be supported by #TheCureStartsNow & their community in advancing #CARTcell therapies at @seattlechildrens.org & @stjuderesearch.bsky.social for children with #braintumors and spinal cord tumors. 🙏❤️🔬 thecurestartsnow.org/news/the-cur...
The Cure Starts Now Funds $1 Million Big Fat Grant to Advance CAR T Cell Therapy for Childhood Brain Cancer | The Cure Starts Now
thecurestartsnow.org
If you told me when I was at @aucmed.bsky.social that I'd apply for an R01 - much less that it would score so well that it would converted to an R37 MERIT award - I dont know what I'd have said. This ones for the Caribbean grads! And thanks to @seattlechildrens.bsky.social and the #NIH! #EndDIPG
Can SNL please invite the Thunder and riff on the Nate Bargatze sketch but with Chet as Lincoln talking about all America’s problems being solved after the civil war
Illinois Gov. JB Pritzker plans to sign an executive order preventing state agencies from obtaining or disclosing data that personally identifies people with autism, unless required for medical care or legal matters. “Every Illinoisan deserves ... the freedom to live without fear of surveillance.”
Dem Governor Launches Plan to Counter RFK Jr.’s Autism Registry
Illinois Governor JB Pritzker has a plan to undermine the autism registry RFK Jr. keeps talking about.
newrepublic.com
NIH's work saves lives—& Trump is gutting it. Straight from D.C. I headed to Seattle Children's to hear from researchers & patients alike about the importance of NIH funding—it's not just about lines in a budget, it's about lifesaving discoveries. We ALL need to speak up to save it.
The #RunofHope is an annual fundraiser for the Seattle Children's #pediatriccancer & blood disorders research. Please consider joining us and/or making a donation. No amount is too small! All donations to our team will go to the Brain Tumor Research Program runsignup.com/cartforkids
Mario CAR Ts for Kids - Run of Hope Seattle
The fact that some brain and spinal cord tumors are incurable is unacceptable. The fact that so many standard treatments have so many side effects is unacceptable. The fact that when tumors recur ther...
runsignup.com
A privilege to publish in Cancer Discovery and to work with amazing colleagues to offer some insight into the current state of the pediatric #CNS #CARTcell field. #AACR25
For more on CAR T cell therapy to overcome barriers in treating pediatric central nervous system tumors, read the review by #AACR25 speaker Andrea Timpanaro (along with @nickvitanza.bsky.social and colleagues) - online now in Cancer Discovery! doi.org/10.1158/2159...
Thrilled to have secured Breakthrough Therapy Designation. This will accelerate our ability to bring #CARTcells to more children with #DIPG and brain & spinal cord tumors.
Breakthrough Therapy designation gives us the possibility to accelerate the development path for BCB-276 as a CAR T-cell therapy to potentially transform treatment of #DIPG, an incurable brain tumor. Our #CARTcells approach opens a new paradigm for other CNS brain tumors. www.brainchildbio.com/press
Seattle Symphony’s A TRIP TO OUTER SPACE vs. Seattle Children’s B7-H3 CAR T CELLS AGAINST DIPG
Out now, the March 2025 cover of @natmedicine.bsky.social! Thank you @sahelisadanand.bsky.social & Nature Medicine team. It’s never been more important to advocate for children’s health, so thank you for bringing awareness to this terrible disease. #DIPG #DMG (Amazing cover artist: Katie Vicari)
Thanks to Dr. Syal & @nbcnews.com for visiting our #CARTcell program to highlight one of our courageous little patients with #DIPG #DMG. So much work left to do but thankful for the support of Seattle Children’s and our brave families. ❤️ www.nbcnews.com/now/video/ex...
Experimental brain tumor treatment shows promise for pediatric brain cancer
Gavin Nielsen, who was 2 years old when he was diagnosed with a rare brain cancer, met Dr. Nicholas Vitanza who is part of a growing group of researchers exploring CAR-T therapy. The treatment program...
nbcnews.com
Thrilled to join this extremely talented group of neuroimmunooncologists working to improve outcomes for children & adults with brain and spinal cord tumors. Thanks to @sitcancer.bsky.social for organizing this summit!! Registration is free so pop in and join us! www.sitcancer.org/education/we...
Respect to @soundersfc.com for their new kit representing the Salish peoples & @acmilanofficial.bsky.social for their new “Dreamland” kit in memory of MLK for black history month ❤️🔥💪🏼
Thank you Washington state for joining this!! #medsky
🧪California and 21 other States sue over the NIH funding cuts. "We are suing President Trump & his administration because they are ... violating the law ... to eviscerate funding for medical research that helps develop new cures & treatments for diseases like cancer ...” oag.ca.gov/news/press-r...
The Not Like Us stuff was entertaining and hilarious, but the overarching protest storyline was perfect. Kendrick is a genius and Samuel L Jackson is a legend. The only halftime show I’ve ever see that I rewatched.
I love that the performance's storyline was about race and how to play the game in America, Kendrick does the opposite of everything Samuel tells him to do and still wins
That’s the funniest thing I’ve ever seen. I love that folks were like “will he play the song???”. Yeah… with Serena Williams dancing, an a minor chain on, and the world’s biggest grin as he stares into the camera. A masterpiece.
The National Institutes of Health plans to severely cut the percentage of its grant money that can be used for overhead costs rather than research.
NIH slashes overhead payments for research, sparking outrage
Move to cut indirect cost rate to 15% could cost universities billions of dollars
scim.ag
With an aim to drive collaborative team science & in honor of our remarkable #CARTcell patients, we started the annual Cleveland Hood Lecture w/ Dr Neev Manoharan of Sydney Children’s Hospital as our inaugural speaker. It’s a privilege to build intercontinental alliances against childhood cancer ❤️🔬
Very excited that #SITC has organized a Summit on Neuro #Immunooncology: From Challenges to Opportunities on Feb. 19, 2025. Honored to speak and to share how quickly and successfully this field has grown. For details, visit: sitcancer.org/Neuro-VS #cancerresearch #immunotherapy #CARTcells
Honored to have our recently published first-in-human phase 1 clinical trial of repeatedly dosed intracerebroventrocular B7-H3 #CARTcells for children with #DIPG highlighted in @theaacr.bsky.social and #CancerDiscovery Research Watch ❤️🔬
BrainChild-03 Trial Supports Safety of B7-H3 CAR T-cell Therapy for DIPG
Main Finding: A phase I trial supported the safety and feasibility of repeated intracranial infusions of B7-H3 CAR T cells for DIPG.Concept: B7-H3 is an immunoregulatory protein expressed on the surfa...
aacrjournals.org
#MedSky #STEM Here’s an interactive tool to show what the NIH does in each state: www.unitedformedicalresearch.org/nih-in-your-...
NIH In Your State - United For Medical Research
Select a state on the map to see the impact of NIH funding across America.
unitedformedicalresearch.org
Big hearts to Costco Diversity has been proven to yield better results.
I will share more soon, but honored on behalf of a huge team and a very brave set of children and young adults to share in #NatureMedicine the first phase 1 trial of repeated intracranial B7-H3 CAR T cells and our very encouraging experience caring for patients with #DIPG.
🌟 NEW in #NatureMedicine: Repeat infusions of B7-H3 #CARTcells were safe in children with diffuse intrinsic pontine glioma (#DIPG). Median OS = 19.8 months vs historical OS = 11 months. 3 patients alive 40 months post-diagnosis! @nickvitanza.bsky.social #OncSky www.nature.com/articles/s41...
Milan!!!!! Nothing like a trophy over Inter - what a win!! #SempreMilan 🔴⚫️
What. A. Comeback. Brilliant from Milan in that second half to turn it around. Question marks over some of our defending, but great character & desire shown to fight back. What a win, what a start for Sergio Conceicao. FORZA. MILAN. ❤️🖤 #SempreMilan #InterMilan #ForzaMilan