Nozhat
@nozhathassan.bsky.social
Evolutionary genetics, R2 retrotransposons | Adelson lab UoA & Collins lab UC Berkeley | 🇦🇺 | Newly Dr. Hassan
I'm excited to share our work providing the first complete mechanistic picture of how R2 proteins nick the second strand, out today in @pnas.org! ✂️🧬 This step in retrotransposition has long been mysterious, but crucial for understanding R2's. Check it out: www.pnas.org/doi/10.1073/... A thread 🧵:
#TEsky My final PhD paper is out! My research started with a paper called 'FakeIDs' where I investigated TE misannotation - so it feels full circle to end with the highs and lows of R2 retrotransposon annotation! Thank you to everyone who cheered me on! rnajournal.cshlp.org/content/earl...
Congratulations to the authors (and my friends), @alex-stuart.bsky.social and Chandler on their paper on CR1 retrotransposons across vertebrates! And thanks for letting me tag along! #TEsky academic.oup.com/gbe/advance-...
Ancient persistence and newfound diversity of CR1-group retrotransposons across vertebrates
Abstract. Retrotransposons are mobile, repetitive DNA sequences that are ubiquitous across eukaryotes and widely recognised as key drivers of both gene and
academic.oup.com
A New Open Foundation for TE Research: GIRI is transitioning the full Repbase collection to an open-access license and joining the Dfam effort to help build a unified open resource for transposable element research. Full announcement: tinyurl.com/48665xss
After a long time finding reviewers, my paper on the evolution of R2 retrotransposons is out! This project was in collaboration with my amazing co-authors Bri and Anthony from the Collins lab. 🐢🐦⬛ Big thanks to my team, especially my supervisor Dave Adelson! #TEsky link.springer.com/article/10.1...
Lineage-specific evolution, structural diversity, and activity of R2 retrotransposons in animals - Genome Biology
Background Retrotransposons play outsized roles in the evolution of gene regulation, genome function, and disease pathogenesis, and more recently they have sparked interest as instruments for new gene...
link.springer.com
New work on CR1 retrotransposons by my lab friends Alex and Chandler! Happy to have helped out along the way
bioRxiv Evolutionary Biology@biorxiv-evobio.bsky.social · 10mo agoAncient persistence and newfound diversity of CR1-group retrotransposons across chordates https://www.biorxiv.org/content/10.64898/2026.01.13.699120v1
Vertebrate retrotransposons are the future of gene therapy. But how do they insert their genes? 🔥🔥 Thrilled to share our new work now published with Kathy Collins, @nogaleslab.bsky.social @berkeleymcb.bsky.social where we investigate this with #cryoEM & biochemistry in 🧪 and cells! #RNAsky #TEsky
