Electrosynthesis of Agrochemicals via Alternating-Current-Driven Selective, Continuous Dehalogenation

Dehalogenation is a critical transformation in chemical synthesis but remains limited by catalyst deactivation and low selectivity in industrial processes. Here, we report an alternating current (AC) ...

pubs.acs.org

Chemistry Department Hosts First Utah Electrochemistry Symposium - Department of Chemistry

Profs. Henry White, Shelley Minteer, and Long Luo hosted the first Utah Electrochemistry Symposium (UTES) on July 25–26, 2025, at the University of Utah’s Department...

chemistry.utah.edu

Missouri S&T awarded five-year $19.8 million grant to lead Center for Chemical Innovation

Missouri S&T has been awarded a $19.8 million collaborative agreement to renew the National Science Foundation’s Center for Synthetic Organic Electrochemistry. This chemical innovation center will be ...

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Origin of Selectivity in Alternating Current-Enabled Partial Reduction of (Hetero)Arenes: A Case Study of Two Consecutive Irreversible Electrochemical Steps

Herein, we investigate the origin of selectivity in the alternating current (AC)-enabled partial reduction of (hetero)arenes to cyclic alkenes. Reduction of (hetero)arenes can be considered as a reaction involving two consecutive irreversible electrochemical steps: the first generates the desired cyclic alkene, while the second leads to its undesired overreduction. Conventional constant current or voltage (DC) electrolysis results in poor selectivity toward the partial reduction products, originating from overreduction and base-induced decomposition of the desired product. Fast-scan cyclic voltammetry shows that the rate constant for the first reduction (k1) exceeds that of the second one (k2). Finite element simulations based on this experimental finding semiquantitatively capture the frequency-dependent selectivity observed in AC electrolysis experiments (i.e., increasing the AC frequency enhances selectivity). The results further reveal that AC electrolysis mitigates the low selectivity by only collecting the products at the initial stage of the reduction reaction, which is mostly under a kinetically controlled regime. We then extend the finite element model and introduce ΔEFOW, the foot-of-the-wave potential difference between cyclic voltammograms of substrate and partial reduction product, as an accessible proxy for k2/k1. A ΔEFOW > 80 mV predicts synthetically useful selectivity (>30%) toward the partial reduction product below 100 Hz.

pubs.acs.org

Meet Anderson’s Lab Postdocs: Q&A with Lokesh and Hugo - Department of Chemistry

We interviewed two postdoctoral fellows, Hugo Samayoa Ovied, and Lokesh Saravanan, to gain insights into what life is like as a postdoc here at U...

chemistry.utah.edu