» The Later Years of Douglas Adams The Digital Antiquarian

filfre.net

Tissue homing and gene expression

I was thinking about my reading habits.

nxn.se

Steering through the clinical trial landscape

Good model performance is only one of many steps towards clinical trial adoption.

hrovatin.github.io

Ghost in the Shell

In the year 2029, the barriers of our world have been broken down by the net and by cybernetics, but this brings new vulnerability to humans in the form of brain-hacking. When a highly-wanted hacker k...

themoviedb.org

Who Funds Misfit Research?

A practical guide

blog.spec.tech

Stem-like T cells are associated with the pathogenesis of ulcerative colitis in humans - Nature Immunology

Li et al. identify a human TCF1-expressing stem-like T cell population that is associated with immune-mediated pathogenesis in ulcerative colitis.

nature.com

Health Technology is Weird

Why it's hard to generalize lessons from the world of therapeutics

blog.spec.tech

Hacking the President’s DNA

The U.S. government is surreptitiously collecting the DNA of world leaders, and is reportedly protecting that of Barack Obama. Decoded, these genetic blueprints could provide compromising information....

theatlantic.com

Research Has Customers

For better or worse, it's time to sell.

blog.spec.tech

» Televising the Revolution The Digital Antiquarian

filfre.net

Single-cell transcriptomics reveals a compartmentalized antiviral interferon response in the nasal epithelium of mice | Journal of Virology

SARS-CoV-2 infects SUS and BGC in the olfactory epithelium, causing an impairment of structural support and integrity of olfactory sensory neurons that can result in severe olfactory dysfunctions. We ...

journals.asm.org

Who writes papers?

There are no actual rules about the order of authorships of papers in academic journals.

nxn.se

Lemon Demon - Ben Bernanke (HD Remastered Music Video)

YouTube video by user400293

youtube.com

Restless Genes

The compulsion to see what lies beyond that far ridge or that ocean—or this planet—is a defining part of human identity and success.

nationalgeographic.com

A Conversation with Jack Scannell: The Intractable ‘Sociotechnical’ Problems of Drug Discovery and Development, Genetic Triumphalism and Predictive Validity

Jack is one of the sharpest thinkers on the pharmaceutical industry, with a talent for coining terms that then propagate among industry insiders and into wider tech circles.

decodingbio.substack.com

F1000Research Article: A guide to creating design matrices for gene expression experiments.

Read the latest article version by Charity W. Law, Kathleen Zeglinski, Xueyi Dong, Monther Alhamdoosh, Gordon K. Smyth, Matthew E. Ritchie, at F1000Research.

f1000research.com

The best experiment doesn't exist

as shown by an analysis of DepMap data

blog.turbine.ai

Beyond classical immunity: Mast cells as signal converters between tissues and neurons

Mast cells act as “signal converters,” translating immunological and tissue signals into host-protective behaviors. They sense antigen and possibly toxins driving avoidance behavior, which can prevent...

cell.com

sciencedirect.com

The Myth of the Well-Rounded Scientist

Despite what grad school admissions committees seem to believe, outside interests are good.

science.org

GEO data unlocks vs paper publication

Occasionally, when a paper is published with a new interesting dataset, the GEO accession is locked as ‘private’ until a certain release date.

nxn.se

Why Are Cells Small?

Two physical constraints — surface area and diffusion — explain why cells are (usually) tiny.

burrito.bio

How China is getting ahead in biotech: a case study

A drug for multiple myeloma should have been an early warning that China is racing ahead in biotech

writingruxandrabio.com

A cautionary tale on biological truths

or how your textbook lies

blog.turbine.ai

FMs and Perturbation Prediction: Good Embeddings vs. Fancy Architectures

elijahcole.me

Scientists and their emotions: the highs ... and the lows

Computational biologist Ewan Birney describes the elation of making a breakthrough while three other scientists tell us how their work plays on their emotions

theguardian.com

A cell is not a spreadsheet- why “Virtual Cells” are still mostly hype

Every few years, biology gets a new phrase that sounds inevitable.

evgenykiner.substack.com

Why Python is the Last Language You'll Have To Learn | Pythonic Perambulations

jakevdp.github.io

The ballad of TIGIT

2.8k words, 12 minute reading time

owlposting.com