Alex Grenning
@ochemgrenning.bsky.social
Associate Professor @UMN. Urgently spreading and learning the OChem Gospel. As a researcher/mentor, I want to (i.) address synthetic challenges associated with CNS disorders and (ii.) invent new reactions of general use to drug discovery.
#GrenningLab members have developed a strategy for preparing 3° and 4° carbons at the 3-position of quinolones! I'm real proud of 'em for advancing this to the submission stage, congrats team! We've posted it to the @chemrxiv.org ! Read about the findings here: chemrxiv.org/engage/chemr...
Aaron and I have decided to do it: #FloHet2026 is a go and we can't wait for the amazing organic chemistry to be shared! More announcements coming soon. Here is our new website. Please share it with the ochem lovers in your life. flohet.org
I am now on #bluesky! #FirstPost to report (tinyurl.com/4n4tyau7) that physicochemically altered variants of (hetero)cyclohexanecarboxylate are accessible by a 2-step 1,3-bis-trifluoromethylation then oxidative malononitrile FGI to carboxylates. We envisage that such building blocks... 1/2
ChemRxiv Bot@chemrxivbot.bsky.social · last yr.Synthesis of 1,3-bis-trifluoromethylated-(hetero)cyclohexane-2-carboxylates Authors: Morgane Mando, Dylan Smith, Jan-Niklas Boyn, Alexander Grenning DOI: 10.26434/chemrxiv-2025-bzjl4