Multimodal imaging of Yasunari nodules in neurofibromatosis type 1

Eye, Published online: 05 August 2026; doi:10.1038/s41433-026-04799-1Multimodal imaging of Yasunari nodules in neurofibromatosis type 1

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Infographic: a randomised, double-masked, placebo-controlled trial evaluating the efficacy and safety of teprotumumab for active thyroid eye disease in Japanese patients

Eye, Published online: 05 August 2026; doi:10.1038/s41433-026-04803-8Infographic: a randomised, double-masked, placebo-controlled trial evaluating the efficacy and safety of teprotumumab for active thyroid eye disease in Japanese patients

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Artificial intelligence is here to stay: the role of scientific etiquette

Eye, Published online: 05 August 2026; doi:10.1038/s41433-026-04801-wArtificial intelligence is here to stay: the role of scientific etiquette

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The cataract that wasn’t: aphakic posterior capsular fibrosis with anterior chamber silicone oil

Eye, Published online: 05 August 2026; doi:10.1038/s41433-026-04785-7The cataract that wasn’t: aphakic posterior capsular fibrosis with anterior chamber silicone oil

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Nd:YAG laser membranolysis of a fibrin membrane occluding an AADI-250 tube

Eye, Published online: 05 August 2026; doi:10.1038/s41433-026-04783-9Nd:YAG laser membranolysis of a fibrin membrane occluding an AADI-250 tube

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Ocular surface and meibomian gland changes following repeated exposure to 5% povidone-iodine during intravitreal injections

Eye, Published online: 05 August 2026; doi:10.1038/s41433-026-04798-2Ocular surface and meibomian gland changes following repeated exposure to 5% povidone-iodine during intravitreal injections

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The “Tap–Drain” model of central serous chorioretinopathy: Mechanistic staging and a Corrective Action-Preventative Action-based framework for disease modification

Central serous chorioretinopathy (CSCR) has traditionally been regarded as a self-limiting disorder and classified using duration- or phenotype-based frameworks. Accumulating clinical and imaging evidence, however, suggests that CSCR is a recurrent disorder in which choroidal haemodynamic abnormalities and retinal pigment epithelium (RPE) dysfunction interact to determine long-term structural and functional outcomes. We synthesize current advances in choroidal physiology and multimodal imaging to propose the Tap–Drain model, a physiology-based conceptual framework that reconceptualizes CSCR as a disorder of outer retinal fluid homeostasis.

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Senate confirms Schwartz as CDC director

Erica Schwartz, MD, JD, MPH, will become the first full-time director of the CDC in nearly 1 year after senators confirmed her to the post on Wednesday, largely along party lines. Senators voted 51-44 in favor of Schwartz’s confirmation, with all Republicans voting “yea” and all Democrats except Sen. Tim Kaine, D-Va., voting “nay.” Five senators — two Democrats and three Republicans — did not vote. Kaine was also the only Democrat who in committee last week. Schwartz served as deputy surgeon general during Trump’s first presidential term. She spent 24 years as an occupational medicine physician

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Senate confirms Schwartz as CDC director

Erica Schwartz, MD, JD, MPH, will become the first full-time director of the CDC in nearly 1 year after senators confirmed her to the post on Wednesday, largely along party lines. Senators voted 51-44 in favor of Schwartz’s confirmation, with all Republicans voting “yea” and all Democrats except Sen. Tim Kaine, D-Va., voting “nay.” Five senators — two Democrats and three Republicans — did not vote. Kaine was also the only Democrat who in committee last week. Schwartz served as deputy surgeon general during Trump’s first presidential term. She spent 24 years as an occupational medicine physician

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Newton launches lenses aimed at computer use, office work

PHOENIX — Two new eyeglass lenses aimed at supporting comfortable computer screen use and office work, Sequel Computer and Sequel Meeting, are now available from Newton. Both lenses feature Newton’s convergence boost technology, which works to reduce the burden on eye muscles caused by convergence movements during screen use, according to the company. Sequel Computer lenses are intended for people who spend hours every day using computers. Half the lens’ total add power is located at the fitting point, with an optimal viewing distance of up to 4 feet, according to a press release. Sequel Meeting

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Image-based AI for Automated Diagnosis and Clinical Activity Grading in Thyroid Eye Disease: A Systematic Review and Meta-analysis

To evaluate diagnostic accuracy of image-based AI for thyroid eye disease (TED) diagnosis and clinical activity grading (CAS ≥3 vs

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Risk of Pediatric Eye Disease in Children with Neurodevelopmental and Behavioral Disorders in the United States

To evaluate the association of neurodevelopmental disorders (NDDs) and behavioral disorders with amblyopia, myopia, strabismus, and strabismus surgery rates.

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Cup-to-disc ratio in GLP-1 RA Associated Non-Arteritic Anterior Ischemic Optic Neuropathy

First: to determine whether the cup-to-disc ratio (CDR) of patients with GLP-1 RA associated nonarteritic anterior ischemic optic neuropathy (NAION) is similar to the CDR of NAION patients without GLP-1 RA exposure. Second: to stratify the odds of developing NAION based on CDR.

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Weekly Journal Update — August 5, 2026

Increased IOP in wind instrument players, possible mechanism of cystoid macular edema in retinitis pigmentosa, phase 1 study of topical laquinimod eyedrops, transient vision loss and risk of major cardiovascular events, ocular symptoms of Loeys-Dietz syndrome.

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Warren Foust named president, CEO of STAAR Surgical

Editor’s note: This is a developing news story. Please check back soon for updates. STAAR Surgical appointed Warren Foust as president and CEO, according to a press release. In addition, Foust joined STAAR’s board of directors. Foust began serving as president and chief operating officer in March 2025 and in February took on the role of interim co-CEO with Deborah Andrews. STAAR also announced that Andrews has been appointed as executive vice president while continuing to serve as chief financial officer. In the announcement, the company highlighted its continued focus on its “three principal

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Warren Foust named president, CEO of STAAR Surgical

Editor’s note: This is a developing news story. Please check back soon for updates. STAAR Surgical appointed Warren Foust as president and CEO, according to a press release. In addition, Foust joined STAAR’s board of directors. Foust began serving as president and chief operating officer in March 2025 and in February took on the role of interim co-CEO with Deborah Andrews. STAAR also announced that Andrews has been appointed as executive vice president while continuing to serve as chief financial officer. In the announcement, the company highlighted its continued focus on its “three principal

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Integrating opportunistic ocular diseases screening into general health examination in Chinese: a multicentre study

Background/aims Cost-effective screening models for ocular diseases in large populations remain a critical challenge for blindness prevention. Our preliminary study demonstrated the feasibility of opportunistic glaucoma screening integrated into general health examinations. This study aimed to evaluate the efficacy of this model for fundus disease screening in a multicentre, large-sample Chinese population.Methods This study was conducted in five health examination centres from four provinces of China. Chinese participants aged ≥18 years undergoing routine health examinations were invited to complete bilateral presenting visual acuity and non-mydriatic fundus photography. Fundus photography was assessed by two experienced graders. Proportion of fundus diseases/changes were calculated. Costs for the screening were also assessed.Results A total of 63 935 eligible participants (age 45.4±14.0 years, 51.3% men) were enrolled. The top five diseases/changes were non-macular drusen (8.80%), macular degeneration (6.30%), glaucoma suspect (5.54%), epiretinal membrane (3.92%) and diabetic retinopathy (3.89%). The proportion of low vision and blindness in the total population was 5.85% and 0.15%, respectively. The top five diseases/changes with vision impairment were retinitis pigmentosa (18.18%), myopic retinopathy (16.52%), macular hole (11.76%), non-glaucomatous optic neuropathy (7.25%) and glaucomatous optic neuropathy (6.37%). The unit cost of screening a single case and an ocular disease suspect was US$22.2 (US$15.7 to US$26.7) and US$83.2 (US$58.7 to US$99.9), respectively.Conclusions This health examination centre-based screening model is feasible, effective and affordable for detecting multiple fundus diseases in large populations. As the model is promoted and its coverage expands, screening costs may be further reduced.

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No-History IOL Power Calculation After Myopic Laser Vision Correction: A Multicenter Retrospective Database Study of 14 Formulas With and Without Posterior Corneal Curvature

To investigate intraocular lens (IOL) power formulas in eyes with prior myopic laser vision correction (M-LVC).

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Pseudohypopyon following Triamcinolone and Silicone Oil Tamponade in a Phakic Eye

A 61-year-old man presented with a zone II/III open globe injury, repaired by primary closure. He subsequently underwent pars plana vitrectomy with endolaser and direct perfluoro-octane-to-silicone oil (5000 cs) exchange for a total retinal detachment with grade C proliferative vitreoretinopathy. Intravitreal triamcinolone acetonide was injected intraoperatively before oil instillation; the eye remained phakic, and prone positioning was advised.

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Preloaded Descemet membrane endothelial keratoplasty: A systematic and descriptive review of global experimental and clinical outcomes

Preloaded Descemet membrane endothelial keratoplasty (plDMEK), in which eye-bank validated donor tissues are prepared, folded, and loaded into delivery devices prior to shipment, has emerged as a promising strategy to standardize and expand access to endothelial keratoplasty. Protocols developed with both endothelium-in (endo-in) and endothelium-out (endo-out) loading configurations have shown to improve surgical efficiency, reproducibility, and tissue utilization while lowering procedural barriers.

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Robots will enhance surgery, not replace humans

Click here to read the Healio Exclusive, “Embrace the future’ of robotics in ophthalmology.” I wrote an earlier perspective on the application of robotics to eye surgery in the April 25, 2024, issue of Healio | OSN. Since that time, significant progress has been made, including completion of the first in-human robot-assisted cataract surgery by two leading companies in the field, Horizon Surgical Systems and ForSight Robotics. In addition, I have participated in several meetings in which the application of robotics to eye surgery has been discussed and debated in the main sessions and between

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Robots will enhance surgery, not replace humans

Click here to read the Healio Exclusive, “Embrace the future’ of robotics in ophthalmology.” I wrote an earlier perspective on the application of robotics to eye surgery in the April 25, 2024, issue of Healio | OSN. Since that time, significant progress has been made, including completion of the first in-human robot-assisted cataract surgery by two leading companies in the field, Horizon Surgical Systems and ForSight Robotics. In addition, I have participated in several meetings in which the application of robotics to eye surgery has been discussed and debated in the main sessions and between

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Response to Letter to the Editor: Retinopathy of Prematurity Training Should Be Judged by Competence, Not Exposure Alone

Dear Editor,

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Cancer Type–Specific Risks of Retinal Vascular Occlusion: A Nationwide Population-Based Study

To evaluate the incidence and risk of retinal artery occlusion (RAO) and retinal vein occlusion (RVO) in cancer survivors across anatomical cancer subgroups.

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Optimising the patient pathway for macular conditions requiring intravitreal injections

Macular disease is the leading cause of vision loss in the United Kingdom, affecting nearly 1.5 million people. Vascular endothelial growth factor (VEGF) has a major role in the onset and progression of vision-threatening macular conditions such as neovascular age-related macular degeneration, diabetic macular oedema and retinal vein occlusion. Anti-VEGF treatments, given by intravitreal injection, can prevent vision loss and may improve vision but must be started quickly before sight loss is irreversible. Informed by an observational study using Hospital Episode Statistics and the Emergency Care Data Set in England and a Costed Integrated Patient Scenario, we identify issues within the current pathway in England. Our key recommendations to optimise care and improve patient outcomes include: (1) increasing public awareness of macular disease to reduce late presentation; (2) ensuring the right patients are seen in the right place at the right time by improving quality and priority of optometrist referrals and by specialists directing patients with conditions such as diabetes and hypertension to community optometrists in the first instance; (3) planning for current and future demand and capacity using innovative solutions to manage expected increases in medical retina conditions and (4) ensuring patient-centred care. Our evidence should encourage National Health Service organisations at all levels to review macular disease pathways to address immediate issues and plan for the future. A shift in care delivery is needed, embracing scalable sustainable solutions, earlier diagnosis and treatment, improved access to more durable therapies, wider adoption of digital technologies and care closer to home.

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Association Between Baseline Smoking Exposure and Incident Branch Retinal Vein Occlusion: A Retrospective Cohort Study

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Neighborhood Socioeconomic Deprivation and Adherence to Diabetic Retinopathy Screening Guidelines

Screening for diabetic retinopathy is imperative to prevent irreversible vision loss. Features to identify patient populations at higher risk for nonadherence to screening guidelines is key to improving visual outcomes. The purpose of this study was to evaluate the association between Area Deprivation Index(ADI) and adherence to diabetic retinopathy screening in a nationwide sample of patients.

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Risk of glaucoma among patients using tadalafil for lower urinary tract symptoms: a multinational cohort study

Aim To evaluate the association between tadalafil use for lower urinary tract symptoms (LUTS) and the risk of developing glaucoma.Methods This multinational, retrospective cohort study was conducted using the TriNetX database. Men aged ≥40 years with a history of LUTS were enrolled between 2012 and 2022. Individuals with a history of glaucoma prior to cohort entry were excluded. Participants were categorised into the tadalafil group and the non-phosphodiesterase type 5 inhibitor (non-PDE5i) group. Propensity score matching (1:1) was conducted to balance age, race, comorbidities, renal function and concomitant medications. Hazard ratios (HRs) were estimated for incident glaucoma of different subtypes and initiation of glaucoma treatment.Results The cohort included 36 927 tadalafil users and 36 927 matched non-PDE5i users. Up to 5 years, tadalafil use was associated with an increased risk of glaucoma compared with non-PDE5i use (HR 1.22; 95% CI 1.12 to 1.33). Elevated risks were observed for ocular hypertension (HR 1.32; 95% CI 1.06 to 1.65), primary open-angle glaucoma (HR 1.33; 95% CI 1.05 to 1.67) and initiation of glaucoma treatment (HR 1.33; 95% CI 1.20 to 1.47). No significant associations were found for low-tension or primary angle-closure glaucoma. Tadalafil users had a higher 5-year cumulative incidence than non-users (3.93% vs 3.16%; p50 years, white population and across comorbidities, remaining robust to 1-, 3- and 6-month lag times.Conclusions Tadalafil was associated with increased risk of glaucoma compared with non-PDE5i in males with LUTS. Ophthalmic evaluation and follow-up may be considered, particularly in patients with risk factors for glaucoma.

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Response to: ‘Comment on: ‘Patient experience of and barriers to the eye examination”

Eye, Published online: 04 August 2026; doi:10.1038/s41433-026-04790-wResponse to: ‘Comment on: ‘Patient experience of and barriers to the eye examination”

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Real-world comparative effectiveness of faricimab versus aflibercept 2 mg in treatment-naïve exudative neovascular AMD patients treated with a treat-and-extend regimen

Eye, Published online: 04 August 2026; doi:10.1038/s41433-026-04710-yReal-world comparative effectiveness of faricimab versus aflibercept 2 mg in treatment-naïve exudative neovascular AMD patients treated with a treat-and-extend regimen

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