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Owen Marshall

@owenmarshall.bsky.social

Principal Research Fellow at the Menzies Institute for Medical Research, University of Tasmania Leads a research group investigating the epigenetics and transcriptional regulation of neural development and disease https://www.marshall-lab.org

19 Posts42 Follower34 Folgt
Owen Marshall@owenmarshall.bsky.social · 10mo ago

I'm thrilled to announce damidBind, our new R/Bioconductor package for analysing differential binding in DamID datasets, and its accompanying preprint. www.biorxiv.org/content/10.6... marshall-lab.org/damidBind/

damidBind: an R/Bioconductor package for differential DamID analysis and data exploration

Summary: DamID, and its cell-type specific adaptations, including Targeted DamID (TaDa), Chromatin Accessibility TaDa (CATaDa) and NanoDam, are now widely-adopted as techniques for the genome-wide pro...

biorxiv.org

Owen Marshall@owenmarshall.bsky.social · 2y ago

Excited to share our latest work, just out in #GENETICS. We show that neuronal & glial GAL4 driver activity changes dramatically over adult life, raising key questions for aging & neurodegeneration research. academic.oup.com/genetics/art...

Dynamic changes in neuronal and glial GAL4 driver expression during Drosophila aging

Abstract. Understanding how diverse cell types come together to form a functioning brain relies on the ability to specifically target these cells. This is

academic.oup.com