Further, we translated the PNECRs for water environments into PNECRs in soil 🌱 and compare both PNECRs to publicly available measured environmental concentrations to determine the current risk these chemicals pose.
Andrew Singer
@oxonandrew.bsky.social
Environmental Microbiologist, Pollution Scientist; 327.66 ppm CO2 #AMR #OneHealth #WBE #CSO Previously: https://twitter.com/OxonAndrew https://www.ceh.ac.uk/staff/andrew-singer
Here we determined predicted no effect concentrations for resistance (PNECRs) for antifungal compounds 💊 in water environments 🌊 from MIC data 🧫. We used an enhanced methodology that considers censored nature of MIC data.
Our latest paper has just been published in Environment International! Check it out here ➡️ www.sciencedirect.com/science/arti... @ukceh.bsky.social @ukceh-moleco.bsky.social
Predicting antifungal concentrations that select for resistance: an enhanced approach to establish environmental thresholds
Antifungal resistance (AFR) is an emerging threat. Understanding the concentrations at which antifungals select for resistance is critical for guiding…
sciencedirect.com
@hollytipper.bsky.social & @rachelapayne.bsky.social led work investigating global trends in the literature on #AMR 🧫🦠in wild animals 🦆🦌🦊 and plants 🌿 @istanton.bsky.social @jenmgshe.bsky.social @oxonandrew.bsky.social @danread.bsky.social www.nature.com/articles/s44...
🗓️ Time for our March wrap up!🌷☀️ Check out what we've been up to ⬇️ @ukceh.bsky.social
@oxonandrew.bsky.social & @istanton.bsky.social travelled to the University of Lincoln meeting for a project meeting for their NERC Seedcorn project on modelling AMR in the environment 🦠🌊. Check out a blogpost on the meeting here: graziellaiossa.weebly.com/news/worksho...
Such an important question. We are at an inflection point and understandably unsure how to proceed. The reality is, TODAY,AI will do things better than many reviewers. TOMORROW it will review better than all reviewers. Do we ignore this reality, if not, how do we transition?
A reviewer just very clearly used AI to write a review. What do I do (as an author)?
Is wastewater surveillance the missing link in our response to #AMR? On the fourth day of #WAAW, our Hub’s co-directors Davey Jones (Bangor University) & @oxonandrew.bsky.social (UKCEH) share their thoughts on this topic. Read more here: www.digitalamr.org/blog/waaw25-...
We are proud to sponsor Panacea: a play co-written by our Hub’s Co-Director, @oxonandrew.bsky.social 👏 Catch the final showings in London and Liverpool to round off this year’s #WAAW! Tickets: linktr.ee/panaceaplay
PANACEA | Instagram | Linktree
Panacea is a tragedy play about a brilliant scientist who creates an infectious vaccine that could save humanity from a future pandemic.
linktr.ee
Our recent paper on #stakeholder opinions on the delivery of environmental components of the UK's #AMR National Action Plan has been written up into a blog! 🦠🌊 Check out the paper here: www.tandfonline.com/doi/full/10.... And the blog below ⬇️ @oxonandrew.bsky.social @hollytipper.bsky.social #WAAW
Stakeholder views on the implementation of the UK’s Antimicrobial Resistance (AMR) National Action Plan (2019–2024) in relation to AMR in the environment
Antimicrobial resistance (AMR) in the environment is an important component of One Health AMR research and is increasingly incorporated into AMR National Action Plans (NAPs), including the UK’s AMR...
tandfonline.com
What was missing from the #UK #AMR National Action Plan? ✍️🎯 Better evidence & clear objectives to help understand & combat the role of environmental factors in driving #AMR in the #UK. 👉 bit.ly/4pkL5Qc @lshtmamrcentre.bsky.social @hollytipper.bsky.social @istanton.bsky.social #WAAW2025
On the last day of #WAAW 🔔 💊, some historians gave to me … ...a major review of the political-economic factors & concepts shaping #antimicrobial innovation since 1980 - and a call to diversify #antibiotic #R&D moving forward! www.cambridge.org/core/journal... For a summary, see the thread (1/9)
Historicising the “Empty Pipeline”: How Antibiotic Innovation Became a Market Failure (1980–2024) | Public Humanities | Cambridge Core
Historicising the “Empty Pipeline”: How Antibiotic Innovation Became a Market Failure (1980–2024) - Volume 1
cambridge.org
From sewage to soil: More monitoring and evidence is needed to understand how environmental resistance is fueling antimicorbial restistance. Read about stakeholders' perspectives of the UK National Action Plan. 👉 tinyurl.com/588csxnc @oxonandrew.bsky.social @piru-lshtm.bsky.social
#WAAW2025 is nearly here & with it the annual surge of #AMR articles. But do current #antimicrobial stewardship schemes adequately address our #planetarycrisis & protect the microbiota we all rely on? Read more in this review of microbial governance approaches: www.cambridge.org/core/journal...
Overwhelming Complexity? Entering a New Era of Microbial Governance | Public Humanities | Cambridge Core
Overwhelming Complexity? Entering a New Era of Microbial Governance - Volume 1
cambridge.org
Happy World #AMR Awareness Week! #WAAW #WAAW25 At @ukceh.bsky.social our AMR researchers work on both #bacterial and #fungal AMR! We undertake research monitoring AMR in many different environments (water 🌊, wastewater 💩, air 💨, soil 🌱 & plants 🌿), which means we get out in the field a lot!
Get your tickets! Panacea: a powerful new play co-written by our Deputy Director, Andrew Singer & writer Christina James is touring the UK 🎭 Panacea follows Gus, whose discovery of an infectious vaccine could save humanity from future pandemics. Find out more: www.digitalamr.org/blog/panacea...
“Panacea”: Antimicrobial Resistance meets theatre through an exploration of ethics and discovery — Digital Health Hub for AMR
digitalamr.org
Shout out to University of Birmingham folk: A science-themed play that I co-wrote is coming to you at the Midlands Art Centre on the 17th. A lab-night out? See you there! 🤞 linktr.ee/panaceaplay @wvschaik.bsky.social @alanmcn1.bsky.social @drjorhodes.com @jkreft.bsky.social
First, a CENTA project investigating whether fungicide residues in compost are capable of increasing #AMR in environmental, opportunistic pathogens 🌱🧫 Details here ⬇️ centa.ac.uk/studentship/... @oxonandrew.bsky.social @openuniversity.bsky.social @imperialcollegeldn.bsky.social #EnvironmentAgency
2026-UKCEH03 Are fungicide residues in compost increasing AMR in environmental, opportunistic fungi? – CENTA
centa.ac.uk
Our Planet. Decoded. UKCEH makes sense of environmental complexity to power decisions that shape a better future. We don’t just examine our planet, we decode it – working out how to build a better tomorrow. 🎞️ youtu.be/s9fBwN5-kxM #UKCEH #EnvironmentalScience 🧪
Introducing UKCEH. Our Planet. Decoded.
YouTube video by UKCEH
youtu.be
"Too often #AMR is framed as an immense although conceptually simple challenge: delay resistance to current drugs and produce new drugs. But we need to go beyond this, we need to pull every lever at our disposal to minimise infection even before we turn to drugs." www.thelancet.com/journals/lan...
AMR is more complicated than a lack of drugs
Later this month (Nov 18–24) is World AMR Awareness Week (WAAW), the annual reminder of this long smouldering crisis in modern health care. This is the first year with the new name as it was formerly ...
thelancet.com
@oxonandrew.bsky.social has been on a paper publishing streak recently! As well as the above he has also published a paper on emerging contaminants in urban streams in Sub-Saharan Africa 🧪💊💧 check it out here: www.sciencedirect.com/science/arti...
Effect-based and (non-)target chemical analyses reveal concerning levels of emerging contaminants in urban streams in Sub-Saharan Africa
Water contamination by micropollutants is a global issue, yet there is limited information from low-income regions. To address this, we evaluated surf…
sciencedirect.com
...AND a comment piece in @lancetmicrobe.bsky.social titled "Diagnostics at the frontline: using the Public Accounts Committee report to catalyse the UK's antimicrobial resistance diagnostic strategy" 🧫🦠💊 www.sciencedirect.com/science/arti... @oxonandrew.bsky.social #AMR
Diagnostics at the frontline: using the Public Accounts Committee report to catalyse the UK’s antimicrobial resistance diagnostics strategy
sciencedirect.com
And the sky was happy until it heard about the coastal storm that’s coming.
@istanton.bsky.social is an Environmental Molecular Microbiologist with a particular interest in dissemination, selection & transmission of both bacterial and fungal #AMR. Isobel has undertaken numerous pieces of work for policy, including an evaluation of the UK’s AMR National Action Plan 🦠🍄🧬
The work on evaluating the UK's #AMR National Action Plan was recently published which focused on stakeholder opinions on the implementation of the 2019-2024 plan 🦠 Check it out below ⬇️ www.tandfonline.com/doi/full/10.... @hollytipper.bsky.social @oxonandrew.bsky.social @rebeccaglover.bsky.social
Stakeholder views on the implementation of the UK’s Antimicrobial Resistance (AMR) National Action Plan (2019–2024) in relation to AMR in the environment
Antimicrobial resistance (AMR) in the environment is an important component of One Health AMR research and is increasingly incorporated into AMR National Action Plans (NAPs), including the UK’s AMR...
tandfonline.com
@istanton.bsky.social is an Environmental Molecular Microbiologist with a particular interest in dissemination, selection & transmission of both bacterial and fungal #AMR. Isobel has undertaken numerous pieces of work for policy, including an evaluation of the UK’s AMR National Action Plan 🦠🍄🧬
Andrew's latest paper was published today, titled: "Environmental hazards from pollution of antibiotics and resistance-driving chemicals in an urban river network from Malawi" 💊🌊 Check it out here ⬇️ www.nature.com/articles/s44...
Environmental hazards from pollution of antibiotics and resistance-driving chemicals in an urban river network from Malawi - npj Antimicrobials and Resistance
npj Antimicrobials and Resistance - Environmental hazards from pollution of antibiotics and resistance-driving chemicals in an urban river network from Malawi
nature.com
@oxonandrew.bsky.social is a Senior Environmental Microbiologist who's research focuses on how pollution impacts microbial ecology, ecosystem function, & human health. He leads research on environmental #AMR, wastewater-based epidemiology & translating findings into policy relevant insights🦠💩
Through the application of cutting-edge molecular techniques, @lindsaynewbold.bsky.social specialises in the investigation of microbial & environmental DNA changes in response to ecological & chemical perturbations, in environments ranging from mountain soils, ground water, air & even honey 🧬🍯🌱💧
@laurens-colours.bsky.social is a Molecular Ecologist & award-winning artist. Her research focuses on #eDNA for #biodiversity monitoring, including invasive/endangered species, community science & integration into policy. She also creates art & animations to communicate ecology & conservation 🧬🎨👩🎨
@amycthorpe.bsky.social is a Molecular Ecologist & uses molecular techniques to study how microbes respond to environmental change. Amy is currently investigating the impact of nutrients & organic matter on microbes in lakes & rivers & is using ancient DNA to reconstruct past microbial communities🧬🦠
Alex Lewis is joining UKCEH this month as a Molecular Microbiology Research Assistant. Alex will be working on a range of UKCEH’s #AMR projects. Previously, Alex was undertaking a Master’s at @lshtm.bsky.social where her research was investigating resistant E. coli from pig farms in Vietnam 🦠🐷🚜
@tessacrosbie.bsky.social is a Molecular Biology Research Assistant at UKCEH Wallingford. Tessa explores how wastewater and biosolids treatment processes impact microbial communities within receiving environments, with a particular focus on the development and spread of #AMR 🦠💩🌊