Institut Pasteur de Bangui
@pasteurbangui.bsky.social
🔬 Institut Pasteur de Bangui (IPB) Protecting lives & advancing science across Central Africa since 1961. 🧬 Research, diagnostics, Infectious diseases, genomics & One Health training. 💬 Follow for science stories & health insights. #Research
First whole-genome sequencing of hepatitis E virus strains from the Central Af. Republic: four HEV-1e genomes from the 2018-2019 outbreak form a distinct cluster among sub-Saharan strains, consistent with local transmission. IPB Ă— @hoppaulbrousse.bsky.social. Open access doi.org/10.1128/mra.00932-26
When a child has a fever and the malaria test comes back negative, the question is still open: what is making this child ill? IPB and its partners have trained the study site teams on a clinical decision-support tool, tuned on data collected in the Central Af. Republic. lnkd.in/esFEtHiw @unistra.fr
Equipment alone doesn’t make a lab ready for an outbreak. We met a mission from ECCAS, the Economic Community of Central African States, which is drafting a regional health policy. Our takeaways: bring diagnostics closer to at-risk areas, invest in trained and retained staff... lnkd.in/ewE6wTdm
Renforcer les laboratoires en Afrique centrale : de l’équipement à la capacité d’agir sur le terrain
Face aux épidémies, disposer d’un laboratoire performant ne suffit pas. Encore faut-il que le diagnostic soit accessible au plus près des zones exposées, que les personnels soient formés pour le réali...
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Sleeping sickness cases have fallen sharply in CAR. Is the decline real or are cases being missed ? At the national programme’s request, FOCAL is strengthening diagnosis & surveillance at 10 facilities on the southern border. IPB is a partner www.linkedin.com/feed/update/... @itmantwerp.bsky.social
Through a Calmette and Yersin fellowship, a technician from our Medical Entomology Lab took the IVTAP course at @pasteur.fr with @ird-fr.bsky.social: vector identification, MALDI-TOF, NGS blood-meal analysis, One Health. Capacity meant to circulate. #OneHealth #MedicalEntomology @pasteurnetwork.org
IPB benchmarked the hepatitis E diagnostic tools available in the Central African Republic against reference assays. Adjusting the IgM cut-off sharply improves specificity — prospective validation still needed. doi.org/10.1186/s128... hoppaulbrousse.bsky.social @pasteurnetwork.org
Institut Pasteur de Bangui hosted a French exploratory mission on 7 September to assess a joint study on antimicrobial resistance surveillance. Routine lab data covers the patients whose samples reach us — the study would test how far those findings generalise. lnkd.in/dmUadfT3 @pasteurnetwork.org
Two studies conducted in 2024 in the Central African Republic — Boali and Bangui — have just been published on antimalarial treatment response and molecular resistance markers in children. Parasitology Lab, IPB, contributed to both. doi.org/10.48327/mts... · @pasteurnetwork.org
New in Peer Community Journal: ViroSeek, an open and reproducible pipeline for detecting viruses in second-generation sequencing data from target-enriched libraries — built for reliable arbovirus surveillance. Co-authored by Nicolas Berthet (Scientific Director, IPB). 📄 DOI 10.24072/pcjournal.767
The Central African Republic has defined its national health research priorities. Research should start from what health programmes need to know — not from topics external partners bring ready-made. Bangui, 24–28 August, with Africa CDC and the Ministry of Health and Population. @pasteurnetwork.org
From 12–14 Aug 2026, IPB trained Central African researchers in malaria modelling — turning epidemiological data into decision-making tools for public health. A national modelling community in the making, with a strong focus on early-career scientists (40% women). @ammnetwork.bsky.social
New national study in Vaccine (2026, open access): in the Central African Republic, 34.5% of children who receive the first pentavalent dose don't complete the third. The challenge is follow-up, not just access. Étude en accès libre : doi.org/10.1016/j.va...
@pasteurnetwork.org study tracks antimicrobial resistance in urinary E. coli and K. pneumoniae across 6 African countries, including the CAR. In Bangui, first-line options are largely compromised — but last-resort carbapenems remain effective. The window for action is still open. lnkd.in/ebsDRSyx
New review in European Journal of Medical Research on epigenetic reprogramming in HPV-associated cancers: methylation signatures, histone marks, ncRNA deregulation — and which biomarkers are actually validated. Institut Pasteur Tunis / Paris / Bangui. doi.org/10.1186/s400... more lnkd.in/epgy-3Zs
Stunting affects nearly 4 in 10 under-5s in the CAR. IPB is working to understand why. Within AFRIBIOTA, stunted children were found to have a small-intestinal overgrowth of bacteria that normally live in the mouth and throat — later shown to drive lipid malabsorption. lnkd.in/eh7F9s8g
In sub-Saharan Africa, RSV mortality peaks at 3–4 weeks of life — before most newborns reach their first postnatal visit. Central African Republic data from IP Bangui (Komoyo et al.) contribute to this landmark meta-analysis. Mahmud et al., Lancet Child Adolesc Health, Apr 2026. lnkd.in/enkjqK46
Le défi du VRS en Afrique centrale : loin d’un simple rhume, il tue dès les premières semaines de vie
Il y a une vérité difficile à entendre dans la plus grande étude jamais réalisée sur le virus respiratoire syncytial (VRS) dans les pays à revenu faible et intermédiaire : en Afrique subsaharienne, le...
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⏱️ In an outbreak, the real race isn’t virus vs vaccine — it’s virus vs diagnosis. Detecting early, and close to the field, breaks transmission chains. Institut Pasteur de Bangui is preparing that speed, before the first case. 🔬 #Ebola lnkd.in/eEWCKKYb @pasteurnetwork.org
Une épidémie se gagne ou se perd à la vitesse du diagnostic Pourquoi l’Institut Pasteur de Bangui prépare la rapidité, avant le premier cas Dans une épidémie de fièvre hémorragique, la vraie course…...
Une épidémie se gagne ou se perd à la vitesse du diagnostic Pourquoi l’Institut Pasteur de Bangui prépare la rapidité, avant le premier cas Dans une épidémie de fièvre hémorragique, la vraie course ...
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“I am stronger than prejudice.” On June 19 in Bangui, a patient opened World #SickleCell Day standing tall. Here, nearly 1 in 5 children carry the gene. Sickle cell is neither shame nor curse — it can be screened, treated, lived with. Let’s unite for a generation free of it. lnkd.in/e-P2riPe
🦟 On World #DengueDay, Institut Pasteur de Bangui stands with the @pasteurnetwork.org against dengue. As CAR’s national reference lab, IPB confirmed the country’s first declared outbreak — identifying DENV-1 & DENV-2 — with local sequencing & open data on GenBank. 🔗 www.linkedin.com/posts/pasteu...
🌍 On ASEAN Dengue Day, the Pasteur Network stands — as one — against dengue 🦟  What began as ASEAN Dengue Day has grown into a truly global mobilisation. Today, more than half the world's… | Past...
🌍 On ASEAN Dengue Day, the Pasteur Network stands — as one — against dengue 🦟  What began as ASEAN Dengue Day has grown into a truly global mobilisation. Today, more than half the world's population ...
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🧬 Thirty years without a new polio lab in Africa: detecting the virus meant culturing it. Direct nanopore sequencing lifts that lock — the sequence is now generated on site, in hours. At Institut Pasteur de Bangui, health sovereignty shifts. 👉 lnkd.in/eGESKsbs @imperialcollegeldn.bsky.social
🔬 Detecting Ebola: ✅ Institut Pasteur de Bangui has a Pan-filovirus kit covering Bundibugyo. Precise strain characterization: 🔄 genomic capacity is being built. Preparedness isn’t a state — it’s a trajectory. 👣 #Ebola #PublicHealth @helmholtzhzi.bsky.social @pasteurnetwork.org lnkd.in/eKjwj33Q
Renforcer le diagnostic d’Ebola, étape par étape
À l’Institut Pasteur de Bangui, détecter le virus est acquis ; identifier précisément la souche est la capacité suivante, construite avec ses partenaires Se préparer à Ebola, ce n’est pas tout posséde...
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For Institut Pasteur de Bangui, Ebola is nothing new: its scientists have studied the virus in the Central African Republic since the 1980s. Preparing before the first case doesn’t mean starting from scratch. 🔬 #Ebola lnkd.in/eWXGwgNm
40 ans de surveillance d’Ebola en Centrafrique
Une continuité scientifique, du terrain forestier au laboratoire de référence Face au risque d’importation d’Ebola, une chose mérite d’être rappelée : pour l’Institut Pasteur de Bangui, ce virus n’a r...
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There’s a family of viruses you’ve probably never heard of: enteroviruses C, cousins of poliovirus. For two years, Institut Pasteur de Bangui will map them across the Central African Republic — sequenced in Bangui — to help protect children. 🧬 #Polio lnkd.in/e4UNYakz @pasteur.fr
Cartographie moléculaire des entérovirus C en RCA pour caractériser les partenaires de recombinaison du poliovirus vaccinal
La persistance, en Afrique centrale et de l'Ouest, d'épisodes répétés de poliovirus circulants dérivés de souches vaccinales (cVDPV) — principalement de type 2 — soulève une question virologique préci...
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How do you know it’s really Ebola? Not so simple. Ebola isn’t one virus but a family of strains that differ. The lab detects it broadly, identifies the strain when it can, and sends samples to reference labs to confirm. Recognising it fast is what preparedness is about. lnkd.in/edR8gufX #Ebola
Reconnaître Ebola au laboratoire
Pourquoi toutes les souches ne se valent pas, et comment l’IPB se prépare Face à la menace d’une importation d’Ebola en République centrafricaine, une question simple revient souvent : comment sait-on...
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Reliable rubella detection in CAR = real protection for pregnancies. Institut Pasteur de Bangui's Enteric Viruses & Measles lab is now fully qualified by the US CDC (2025 proficiency tests), with a perfect rubella score & praise for spotting a very low viral load sample. Bravo to the team!
New genomic study: mpox clade Ia in the Central African Republic, 2019–2024. 113 genomes, 7 lineages. Most cluster with DR Congo strains — except Sangha-Mbaéré, which groups with Cameroon/Gabon. Low APOBEC3 = mostly zoonotic, short human chains. 🧬 DOI: 10.1080/22221751.2026.2645863 lnkd.in/epj5-Ux8
Mpox en Centrafrique : ce que l’ADN du virus raconte de la forêt
La mpox, anciennement appelée variole du singe, n’est pas une maladie nouvelle en Afrique centrale. Mais une étude génomique récente menée en République centrafricaine apporte un éclairage précieux : ...
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📣 SAVE THE DATE | JSB3 2026 The 3rd Bangui Scientific Days, will take place in Bangui, Central African Republic, on May 25–27, 2026. Theme: One Health: major challenges, opportunities and perspectives. 🔗 More information, submission and registration: jsb3bangui.org #JSB3 #OneHealth
🔴 Today is #WorldTBDay 2026 In the Central African Republic: 540 TB cases per 100,000 people — 4× the global average. Over 28,000 new infections in 2024. More than 7,000 deaths. At Bangui's hospitals, over 73% of TB patients are also HIV-positive. 👉 lnkd.in/eYnVTEhD
Tuberculose en Centrafrique : la science avance, le combat continue
Chaque 24 mars, le monde commémore un moment fondateur : l'annonce, en 1882, par Robert Koch, de la découverte du bacille responsable de la tuberculose. En 2026, l'OMS a retenu un thème offensif : « O...
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At Institut Pasteur de Bangui, French Foreign Minister Jean-Noël Barrot joined the inauguration of the Environmental Surveillance Laboratory and the foundation stone ceremony for the Institute’s extension. A strong step forward for health sovereignty and regional health security. lnkd.in/eXXwMQ4X
On March 8, 2026, in Bangui, Dr Carine NGOAGOUNI was honored among the “Unsung Heroines.” Institut Pasteur de Bangui proudly welcomes this recognition, which highlights the vital contribution of women to science, public health, and evidence-based action. #IWD2026 #WomenInScience #PublicHealth #CAR
