Well done Janko!

Hypothesis Fund@hypothesisfund.bsky.social · 2w ago

2/ What if a new job changed your personality & extended your life? 🤯 Harpegnathos ants 🐜 do exactly that. Awardee Janko Gospocic is studying the epigenetics behind their caste-transitions, which could unlock new ways to reverse brain aging. 🎉 Congrats Dr. Gospocic! 🙏 #HFScout @planaria1.bsky.social

New paper from the Capelson Lab in collaboration with the @ranganlab.bsky.social where they found that Nup93-2 only partially overlaps with mature NPCs. This off-pore Nup pool helps silence Polycomb domains. 🤩https://www.biorxiv.org/content/10.64898/2026.08.28.747911v1

Distinct functions of Nup93 paralogs in tumor growth and Polycomb-mediated repression of JAK/STAT signaling

Nuclear pore complexes (NPCs) are nuclear envelope (NE)-embedded protein assemblies that mediate nucleocytoplasmic exchange and interact with the genome, including binding of an NPC component Nup93 to...

biorxiv.org

His voice was the soundtrack to nature documentaries I grew up loving. 100 years of David Attenborough. Few scientists or communicators have done more to connect the public with the stakes of biodiversity and climate. Beautiful Nature's editorial @nature.com www.nature.com/articles/d41...

Happy 100th birthday David Attenborough! Nature salutes you

The science communicator has raised awareness of the natural world andits myriad interconnections on which humans depend.

nature.com

New preprint from @novoalab.bsky.social ! Which tRNAs are used by ribosomes during translation? We introduce tRIBO-seq, a nanopore method to sequence ribosome-associated tRNAs and track how the active tRNA pool changes across stress conditions. www.biorxiv.org/content/10.6... Thread 👇

New preprint in collab with Capelson & Schindler labs): Nuclear pore complexes are developmentally removed and rebuilt during oocyte specification. Blocking turnover prevents gene silencing and meiotic entry. Nuclear architecture renewal is required for cell fate. www.biorxiv.org/content/10.6...

It is always delightful to read Juan Valcarcel's thoughts. A very well-deserved Carmen y Severo Ochoa awardee and, even better, a colleague from whom we all learn in seminars and talks. @crg.eu elpais.com/ciencia/2025...

Juan Valcárcel, biólogo molecular: “Cada uno de nosotros es una experiencia única. ¿Qué sentido tiene clonarnos?”

“Una forma de vida sintética no se ha producido aún, que yo sepa, pero no hay ninguna razón por la que no se pueda producir”, dice el científico, premio Carmen y Severo Ochoa de Investigación

elpais.com

Great news in these important days to fight #HIV infection that has taken the life of so many and caused stigma and discrimination.

Nature@nature.com · 10mo ago

Two studies suggest that T cells with stem-cell-like properties could work with antibody therapies to control HIV after a person stops taking antiviral pills go.nature.com/441EK3M

POM121 is one of the transmembrane nucleoporins that anchors the Nuclear Pore to the nuclear envelope. The Rodriguez-Bravo+labs identified a nuclear-soluble pool of POM121 that enhances the aggressiveness of prostate cancer, offering new therapeutic opportunities for this disease. shorturl.at/Z2Ked

Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you. More info: www.crg.eu/en/content/t...

Really cool read - 'New generation of cancer-preventing vaccines could wipe out tumors before they form | Science | AAAS' www.science.org/content/arti...

New generation of cancer-preventing vaccines could wipe out tumors before they form

Shots enter early clinical trials for healthy people at high risk for disease

science.org

Whitehead Institute honors the life and legacy of Nobel Laureate David Baltimore (1938–2025), its Founding Director and a globally revered scientific leader. 1/4 lnkd.in/eUKd4zxh

Great news, providing access to CRISPR therapy for rare diseases in children is giving hope to many families chanzuckerberg.com/newsroom/cen...

Advancing Cures for Rare Diseases

With the launch of the new center, we're one step closer to making personalized CRISPR cures a reality for children born with rare genetic diseases.

chanzuckerberg.com

How are some enhancers able to regulate genes over megabase distances when they usually act in genes over kilobase distances? This is about a cis-element that helps enhancers to increase substantially their genomic interaction capacity.. Cool! www.nature.com/articles/s41...

Range extender mediates long-distance enhancer activity - Nature

The REX element is associated with long-range enhancer–promoter interactions.

nature.com

Introducing Arc Institute’s first virtual cell model: STATE

💜Feliz #11F y #DíadelaMujeryNiñaEnLaCiencia💜

El 8-M de las científicas: miles de mujeres se vuelcan para despertar vocaciones en la niñas

Un movimiento imparable ha arrancado con fuerza: es el sigiloso 8-M de las científicas. Mujeres determinadas a enseñar a las chicas que pueden ser profesionales capaces

lavanguardia.com

Today is #WorldCancerDay, a time to support those impacted, honor the memories of loved ones we've lost, and reflect on the important work we, as scientists, do. This year's message, #CloseTheCareGap," reminds us that equitable access to cancer care is not just a goal; it's a necessity.

This is such a step forward! Kudos to the authors. KRAS is mutated in around 25% of cancers and was considered “undruggable”, being this a good example of how the drug discovery field is being changed quickly with new computing tools and power. Hopefully the impact to patients arrives also soon! 🚀

Akshat Nigam@akshatai.bsky.social · 2y ago

Excited to share our latest work, published this morning in Nature Biotechnology! 🎉 We developed a hybrid quantum computing-enhanced generative model to design KRAS inhibitors. Check it out here: rdcu.be/d68Fs. Some fascinating insights along the way:

Great time with friends and colleagues in our annual retreat of the Di Croce lab north of Barcelona #CRG