Pavo Orepić

@pavoorepic.bsky.social

Postdoc @ University of Zurich PhD @ EPFL Cognitive neuroscientist | computer science background self-voice | auditory-verbal hallucinations | speech | voice acoustics | population dynamics| intracranial EEG

Excited to share that my postdoc work with Timothée Proix @ndlab.bsky.social is now in Nature Communications!🎉 Recording from 624 human neurons, we show that semantic predictions realign phonetic population activity—revealing how meaning feeds back to reshape speech-sound processing. Thread 1/6 👇

Top-down semantic predictions align phonetic neuronal dynamics in human superior temporal gyrus - Nature Communications

How semantic information influences phonetic processing during speech perception remains unclear. Here, the authors show that semantic predictions reshape phonetic representations in human temporal co...

nature.com

Thrilled to share our new conceptual piece on self-voice with Ana Pinheiro: lnkd.in/exKTTZ2e Extensively reviewing self-voice literature, we argue it is not just a sound, but a 5-piece puzzle of the self. We ask what happens when that puzzle breaks apart in clinical conditions—or is reshaped by AI.

Fig. 1. Self-voice building blocks. In (a) natural self-voice perception (during speaking), all five blocks combine to form a complete self-voice representation (puzzle inset). The auditory block (green) processes the acoustic signal (voice waveform). The motor control block (red) generates the voice (downward arrow) and sends sensorimotor predictions to the auditory block (upward arrow) to stabilize perception. The memory block (pink) provides an internal self-voice template for recognizing whether a voice is self-generated or externally generated. The multisensory integration block (blue) incorporates exteroceptive (e.g., bone-conducted vibrations) and interoceptive cues (e.g., respiration). The self-concept block (orange) aligns the perceived voice with personality and social identity. The lack of motor control involvement (incomplete puzzle) and bone-conducted cues in (b) digital self-voices alters perceived voice quality (changed waveform; triangle in the auditory block). In (c) auditory-verbal hallucinations, the blocks fail to integrate properly (distorted puzzle), producing a hallucinated voice (blurry waveform). Disruptions in sensorimotor prediction (triangle in red upward arrow) and in the memory block (pink triangle) contribute to self-other voice confusion.