This work has now been accepted - Congrats to all involved! doi.org/10.1242/dmm.... #Neurodevelopment #Genetics #Zebrafish
Unique and overlapping behavioral effects of isoform-specific NRXN1 deletions
Mutations in the human neurexin 1 (NRXN1) gene are associated with neurodevelopmental disorders including autism and schizophrenia. Vertebrate NRXN1 produces three major NRXN1 isoforms, named α, β, an...
doi.org
Excited to share the first preprint from our lab! Our work examines how isoform-specific NRXN1 deletions—a gene strongly associated with neurodevelopmental disorders—shape sensorimotor and social behavior in zebrafish. www.biorxiv.org/content/10.6... #Neurodevelopment #Genetics #Zebrafish