Pediatric Neurology

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Pediatric Neurology is a monthly journal that provides essential information to child neurologists and others who care for children with neurological disease.

This retrospective review study looks at intrathecal baclofen pump (ITBP) implantation at a single center over a period of 3 years. 43 pediatric patients were implanted with an ITBP. This study analyzed the test dose, the dose-finding process and complications experienced.

Intrathecal Baclofen Therapy in Children: Testing, Dose-Finding, and Complications—A Single-Center Experience

Intrathecal administration of Baclofen, a γ-aminobutyric acid agonist, is an established treatment for spasticity in both pediatric and adult populations, resulting in functional improvements in…

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Work up for spasmus nutans includes ruling out intracranial space occupying lesions or retinal conditions. While traditionally associated with structural lesions, this case highlights an underlying genetic diagnosis. Can you guess what the genetic diagnosis was?

Early Exome Sequencing for an Infant With Paroxysmal Eye Movements Reveals a Monogenic Etiology for Spasmus Nutans

A 5-month-old, full-term, developmentally typical male infant presented with a 2-week history of abnormal rapid eye movements occurring multiple times per day. Parents noted that the patient was…

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In SMA, where "time is muscle", can we use prenatal diagnosis to facilitate ultra rapid treatment initiation after birth? Read this short communication that describes two such cases where prenatal diagnosis led to a lead time of 5-8 days, and therefore early treatment planning and start!

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About a third of patients with pediatric epilepsy, report at least one barrier in adherence to anti seizure medication. This study by Molisani et al looks at what these barriers are in a large cohort of patients. Medication Barriers in Pediatric Patients With Epilepsy -

Medication Barriers in Pediatric Patients With Epilepsy

To identify the most common medication adherence barriers among pediatric patients with epilepsy, standardized screening was implemented in a child neurology division using the Barriers to Adherence…

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