Congratulations to Steve Tong, Josh Davis and the huge SNAP team (including Monash Health). Clear outcome that cefazolin is less nephrotoxic than flucloxacillin for MSSA, and pencillin is better for PSSA. @steventong.bsky.social @gurujosh.bsky.social

Erin McCreary, PharmD@erinmccreary.bsky.social · last yr.

@steventong.bsky.social presents the results of the PSSA domain of the SNAP 🫰 trial - the worlds largest trial of staph aureus bacteremia - at #ESCMID2025 fluclox resulted in higher mortality and more AKI compared to penicillin for PSSA

Cool paper from Florian Kramer & colleagues about a novel feature of circulating H5N1 clade 2.3.4.4. These viruses have a longer stalk in their neuraminidase (NA) enzyme, a key viral protein. This was not seen in past H5N1 strains (2002-2019) Why does it matter?🧪 journals.asm.org/doi/10.1128/...

Clade 2.3.4.4b H5N1 neuraminidase has a long stalk, which is in contrast to most highly pathogenic H5N1 viruses circulating between 2002 and 2020 | mBio

While the truncated version of the N1 neuraminidase stalk domain may be associated with increased virulence in poultry, the long version of the stalk domain has been associated with increased transmis...

journals.asm.org

Looks like PubMed is down - not sure if this is a temporary outage or something more sinister. Europe PMC is an alternative search engine for medical literature that is publicly accessible. europepmc.org

Great list @absteward.bsky.social! Mine is coming soon (limited to 10)

Antibiotic Steward 🅱️C🆔🅿️🌟@absteward.bsky.social · 2y ago

🔥🔥 NEW 🔥🔥 Year In Review: Top Infectious Diseases Articles From 2024 Our new post, a great collaboration with my friend 🌟 @idstewardship.bsky.social 1️⃣6️⃣⚡️🆔 RCTs 7️⃣Syst Reviews/Meta 3️⃣🌏Guidelines ✨️Wiki_Guidelines #idsky #EMIMCC #medsky #utisky EnJoy Share plz! www.idstewardship.com/year-review-...

Paul Sax's "oh wow" moments in HIV: AZT during pregnancy reduces vertical transmission; triple ARVs improve survival; integrase inhibitors as effective salvage therapy; PrEP is very effective; undetectable = untransmissible and now 6 monthly lenacapravir PReP is 100% effective

Paul Sax@paulsaxmd.bsky.social · 2y ago

With the publication of PURPOSE 2 for PrEP in @nejm.org, and the stellar results, I wonder what’s going to happen once it gets approved for this indication. Should be interesting, to say the least! blogs.jwatch.org/hiv-id-obser...

Five years ago (1 Dec 2019), the first person became unwell in a case cluster of a new infection that we now know as COVID-19. pmc.ncbi.nlm.nih.gov/articles/PMC...

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

A recent cluster of pneumonia cases in Wuhan, China, was caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV). We report the epidemiological, clinical, laboratory, and radiologica...

pmc.ncbi.nlm.nih.gov

Congratulations to the BALANCE group on the trial published in NEJM today. This trial tested 7 vs 14 days of antibiotics for bloodstream infection. #IDSky www.nejm.org/doi/full/10....

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections | NEJM

Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non...

nejm.org

Lessons from practice for immunocompromised hosts by Dr Ai Li Yeo and A/Prof Claire Dendle #ForbesWeek #IDSky 1. There can be more than two pathologies in immunocompromised patients

Allen Yung's Golden Rules of ID. Copied over from the Other Place for @kottonnelson.bsky.social #IDSky