New PhD opportunity in the 't Hart group! We are looking for a candidate interested in using a chemical biology approach to study mRNA degradation. The project will focus on AI-generated peptide inhibitors to study mRNA deadenylation. stellen.uni-muenster.de/jobposting/7...

Doctoral Research Associate (Wissenschaftliche*r Mitarbeiter*in,salary level E 13 TV-L)

stellen.uni-muenster.de

We are hiring! Check out our open PhD position for an exciting industry collaboration with Novo Nordisk: jobs.ethz.ch/job/view/JOP...

PhD Position in Peptide-Based Drug Discovery (Industry Collaboration, w/m/d)

jobs.ethz.ch

My first post here on Bluesky! Highlighting our preprint looking at how backbone modifications influence cyclic peptide cell uptake. Turns out it is a balancing act between uptake and biological activity. Great work by first author Joseph Openy and of course all others! chemrxiv.org/engage/chemr...

Single atom substitutions in backbone aromatic groups alter membrane permeability and biological activity of cyclic peptides

Cyclic peptides hold significant potential as disruptors of challenging targets such as protein-protein interactions, but their poor membrane permeability often limits their use for intracellular targ...

chemrxiv.org