Pieter Medendorp

@pmedendorp.bsky.social

Professor of Sensorimotor Neuroscience, Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour

How does the brain integrate artificial body extensions? Using a custom-built finger-extending exoskeleton, we show that wearable augmentations are quickly integrated into body representation, with proprioceptive space adapting to the device’s structure and function. www.biorxiv.org/content/10.1...

Dynamics of sensorimotor plasticity during exoskeletal finger augmentation

How does the brain integrate artificial body extensions into its somatosensory representation? While prior work has shown that tool use alters body representation, little is known about how artificial...

biorxiv.org

👀 Look to your left! Look to your right! I just 'stimulated' your frontal eye fields (FEFs)! 🧠 In our latest study, we developed a temporally precise Transcranial Ultrasonic Stimulation (TUS) protocol to modulate the human FEFs & uncover new insights into brain function!👇 doi.org/10.1101/2025...

Rapid modulation of choice behavior by ultrasound on the human frontal eye fields

A fundamental challenge in neuroscience is establishing causal brain-function relationships with spatial and temporal precision. Transcranial ultrasonic stimulation (TUS) offers a unique opportunity t...

doi.org

New preprint from the lab: Online interference of declarative memory on fast and slow adaptive processes in force field motor learning, by Judith Rudolph and colleagues www.biorxiv.org/content/10.1...

Online interference of declarative memory on fast and slow adaptive processes in force field motor learning

Error-based motor adaptation is currently understood as a dual-rate process involving a fast adaptive process that learns quickly but also decays rapidly and a slow process that learns slowly but has good retention. While the fast process is typically categorized as procedural learning, recent evidence suggests that it relies on the declarative memory system. To test this hypothesis, we investigated in what manner a declarative memory task interferes with two processes that supposedly underly force field adaptation in reaching. This declarative memory task, which involved learning of a list of words, was assessed through either recognition or recall, and was compared to a non-declarative, vowel counting task, using a within-subject design (n=32). We employed a Bayesian hierarchical dual-rate process model to capture the observed force compensation across trials, expecting that the parameters of the fast process would be affected by the declarative memory task. We examined the 95% highest density interval of the posterior distribution of the difference between the experimental and control condition for each parameter. While most parameters remained unaffected by the declarative memory task, the retention rate of the fast process showed a hint of reduction, suggesting a complex interplay between declarative memory and ongoing motor adaptation processes. ### Competing Interest Statement The authors have declared no competing interest.

biorxiv.org