@pmozgunov.bsky.social

A new paper on personalised MTD identification! In Phase I, all patients are assumed to have the same risk of adverse events. What if it might depend on baseline characteristics? Can we add covariates when the small sample is small? The answer is here onlinelibrary.wiley.com/doi/10.1002/...

On Inclusion of Covariates in Model Based Dose Finding Clinical Trial Designs

There is a growing number of Phase I dose-finding studies that use a model-based approach, such as the CRM or the EWOC method to estimate the dose-toxicity relationship. It is common to assume that a...

onlinelibrary.wiley.com

I am looking for a PhD student in Medical Statistics. This project aims to develop new methods for design of early phase trials starting from monotherapy and progressing into combinations. More details are in the link. Feel free to contact me if any questions. www.findaphd.com/phds/project...

Designs for sequences of early phase (modular) studies at University of Cambridge on FindAPhD.com

PhD Project - Designs for sequences of early phase (modular) studies at University of Cambridge, listed on FindAPhD.com

findaphd.com