Our researchers developed a new CAR T-cell, that targets a cancer-driving protein called WT1, which is found inside many leukemia cells and several other cancers. This potentially extends CAR T-cell applications to new cancer types and patient populations. aacrjournals.org/bloodcancerd...

1/ A new blood test-based method developed by researchers at @pmresearch-uhn.bsky.social could detect and classify metastatic breast cancer without the need for invasive tissue biopsies. 🔗 Read more: www.uhnresearch.ca/news/8-04-20...

Through UHN STEM Pathways, 37 high school students gained hands-on research experience and explored their future STEM aspirations. 🔗 This #YouthDay, learn about 4 of these summer students and their experiences at @uhn.ca: www.uhnresearch.ca/news/8-12-20... #NextGenUHN

Instead of relying only on traditional tissue biopsies, our study showed that a simple blood test could detect and classify advanced breast cancer. Led by Drs. Dave Cescon and Sasha Main @uhn.ca Princess Margaret Cancer Centre: doi.org/10.1158/0008...

Congratulations to Dr. Gilla Shapiro on being named one of the Emerging Leaders in Health Sciences by CAHS! Dr. Shapiro's research in psychosocial oncology, behavioural science, and cancer prevention, has influenced policy, practice, and equitable care in Canada and internationally.

🎉 Congratulations to the 2026 Terry Fox New Frontiers Program Project Grant teams who are launching ambitious new #cancerresearch projects with $33M in support from TFRI! Learn more: www.tfri.ca/updates/news...

Congratulations to Dr. Amit Oza on receiving 2026 International Gynecologic Cancer Society (IGCS) Lifetime Achievement Award, for his exceptional contributions to gynecologic oncology through research, clinical leadership, mentorship and international collaboration. www.uhn.ca/corporate/ne...

How do we ensure AI is safe, trustworthy and effective in cancer care and research? Meet Dr. @bhaibeka.bsky.social Executive AI Scientific Director @uhn.ca, Senior Scientist and Scientific Director of Cancer Digital Intelligence program at Princess Margaret Cancer Centre. youtu.be/yIOPi6EK3DM?...

Meet Dr. Benjamin Haibe Kains: Transparent AI Research for Safe Health Care

YouTube video by UHN Research

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Check out the interview with our Senior Scientist Dr. Lillian Siu to get to know more about our SHERLOCK trial!

Research at UHN@uhnresearch.ca · 4w ago

Take a look at how @uhn.ca’s SHERLOCK study—supported by the Peter Gilgan Foundation—is lighting a new path in #PrecisionCare and helping detect cancer recurrence earlier with a blood test. 🔗 Learn more: www.uhn.ca/corporate/Ne... @pmresearch-uhn.bsky.social

Take a look at how @uhn.ca’s SHERLOCK study—supported by the Peter Gilgan Foundation—is lighting a new path in #PrecisionCare and helping detect cancer recurrence earlier with a blood test. 🔗 Learn more: www.uhn.ca/corporate/Ne... @pmresearch-uhn.bsky.social

We are proud to host the 2nd Annual Allan Slaight Breakthrough Forum on Cancer Neuroscience, bringing researchers from @pmresearch-uhn.bsky.social @kbi-uhn.bsky.social @camhnews.bsky.social and for the first time, @sickkidsto.bsky.social to explore the exciting frontiers in medicine.

Our new study led by Dr. David Kirsch @uhn.ca @uhnresearch.ca describes an innovative dual recombinase preclinical model of CIC::DUX4 sarcoma, an aggressive cancer affecting young adults, and identifies a promising treatment approach in lab models. doi.org/10.1172/jci2...

After cancer treatment, one question remains: Is it truly gone? Backed by the Peter Gilgan Foundation, SHERLOCK at @pmresearch-uhn.bsky.social is uncovering cancer earlier—through a simple blood test. 🔗 Read the CBC exclusive: www.cbc.ca/news/health/...

Can you ever truly cure cancer? Canadian researchers are using blood biopsies to find out | CBC News

A Toronto-based team is launching a massive, years-long research project to study liquid biopsies, a novel technology meant to catch tiny traces of tumour DNA in the blood. The goal? Finding better wa...

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Check out our new clinical trial called SHERLOCK that investigates how liquid biopsy can be used to detect cancer recurrence, and seeks to figure out how to use this emerging technology in routine patient care. www.cbc.ca/news/health/...

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Researchers at UHN's @pmresearch-uhn.bsky.social are leading a major effort to bring liquid biopsy technology into routine patient care. The goal: using a simple blood test to detect cancer recurrence earlier and spare patients from costly, invasive treatments. https://bit.ly/4ya2cJF

New hope for anaplastic thyroid cancer, one of the most aggressive and lethal cancers: our study with @lhsccanada.bsky.social shows combining naporafenib and trametinib effectively shuts down cancer growth in lab models, better than standard therapies: doi.org/10.1016/j.xc... @uhnresearch.ca @uhn.ca

1/ New findings from @pmresearch-uhn.bsky.social reveal how DNA sequences called transposable elements can help leukemia stem cells survive treatment and drive relapse, paving the way for new therapeutic strategies. 🔗 Read more: www.uhnresearch.ca/news/6-26-20...

Our researchers developed an artificial intelligence (AI)-based biomarker, called ENLIGHT, that shows promise in predicting immunotherapy benefits across many different cancer types. doi.org/10.1038/s416...; www.marathonofhopecancercentres.ca/impact/news-...

Congratulations to Dr. @bhaibeka.bsky.social on receiving the 2026 inaugural Francis Ouellette Community Award! 🎉 Recognized for his leadership in open science, community building & advancing inclusive, bias-aware AI in computational biology. @uhnresearch.ca @uhn.ca www.linkedin.com/posts/canadi...

AI is transforming health care—but how do we ensure it’s safe, fair, and trustworthy? The Cancer Digital Intelligence team from @pmresearch-uhn.bsky.social has developed AFFRM-AI, a practical framework for responsible #AI in clinical care. 🔗 Read more: www.uhnresearch.ca/news/6-23-20...

Congratulations to our Medical Oncologist & Clinician Investigator Dr. Natasha Leighl on receiving the 2026 Gandara Clinical Research Award from International Society of Liquid Biopsy! This award recognizes outstanding contributions to liquid biopsy research and clinical impact.

Our study shows porphrin-lipid nanoparticles can spot tiny, hidden cancer in the neck more accurately in preclinical models that standard scans often miss, potentially improving how surgeons plan treatment for oral cancer patients. @uhn.ca @uhnresearch.ca www.thno.org/v16p7108.htm

Our new study found that a ctDNA blood test could help identify which patients with early-stage lung cancer (stage I non-small cell lung cancer, NSCLC) are at higher risk of their cancer returning after surgery. doi.org/10.1016/j.jt... @uhnresearch.ca @uhn.ca

Our new study shows that a methylation-based blood test measuring tumour DNA can accurately monitor treatment response & detect signs of treatment failure a median of six months before clinical progression in metastatic breast cancer patients. www.nature.com/articles/s41... @uhn.ca @uhnresearch.ca

Terry Fox-funded researchers have identified blood stem cells that can remember inflammation long after an infection is gone. Stress from inflammation may alter cells behaviour, drive blood cell aging and raise cancer risk. Learn more about this bold Terry Fox-funded research: tinyurl.com/yxwmx88f

Our new study discovered a way to make AML cancer cells behave more normal-like: they differentiate, lose stemness, and become easier to be detected and killed by immune cells—by changing RNA degradation in cancer cell mitochondria. www.nature.com/articles/s41... @uhnresearch.ca @uhn.ca

A new study by @uhn.ca Princess Margaret Cancer Centre and University of Oxford identified a subset of blood stem cells that are shaped by past inflammatory events. These cells can accumulate with age and are linked to mutations with a higher risk of leukemia. www.nature.com/articles/s41...

“People often come out of cancer with a very different lens. They think more about how they want to spend their time and who they want to spend it with,” says Dr. Jennifer Jones. Jennifer's research is reshaping life after cancer: www.uhnresearch.ca/news/5-29-20... www.youtube.com/watch?v=98Y4...

Meet Dr. Jennifer Jones: Reshaping Life after Cancer

YouTube video by UHN Research

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🚨 #NewPublication alert! A new @nature.com study from scientists at @pmresearch-uhn.bsky.social and @ox.ac.uk has discovered that human blood-forming stem cells can “remember” past inflammation—memory that may influence health and disease outcomes. 🔗 Read more: www.uhnresearch.ca/news/5-27-20...

This month, the 15th Annual Princess Margaret Cancer Centre Research Retreat took place to build collaborations among scientists and clinicians, and to accelerate discoveries that will address patient needs. Congratulations to all our 2026 research award winners! www.linkedin.com/feed/update/...

Our Till & McCulloch Paper of the Year Award in Clinical Research honours the study led by Dr. Jennifer Knox that identified actionable pancreatic tumour mutations—for selecting suitable targeted therapies & chemotherapies in pancreatic cancer cases. pubmed.ncbi.nlm.nih.gov/40929627/