What’s the point of estimating fluid responsiveness?

The Thoughtful Intensivist navigates dangerous waters

open.substack.com

Il dolore nella sindrome coronarica acuta - EMpills - Pillole di medicina d'urgenza

Come trattiamo il dolore di un paziente con sindrome coronarica acuta? Vecchie abitudini e nuove tendenze...

empillsblog.com

A Primer on the Perils of Intravenous Fluids – Part 1

Jon-Emile S.

pulmccm.org

The Acidity of Normal Saline and the Stewart Approach

Jon-Emile S.

pulmccm.org

3 Essential ChatGPT Habits Every Doctor Should Master - Passive Income MD Shop

We're sharing 3 essential ChatGPT habits that every doctor should master to save time, improve efficiency, and enhance patient care!

passiveincomemd.com

The Dogtensivist Manifesto

The Thoughtful Intensivist got exclusive access to the manifesto.

thethoughtfulintensivist.substack.com

Why don't oncologists refer to palliative care?

And will their own society's strong recommendation ever change their minds?

pulmccm.org

A Response to the NEJM's Sepsis Review Article

There's no test to "diagnose sepsis." What does that mean for clinical studies and health policy?

pulmccm.org

Can a Guacamole Overdose Kill You? -Part 1

The Skinny on Sitosterolemia?

pauldthompsonmd.substack.com

One Arena Where You Can Bend the Rules to Your Advantage: Clinical Trials

Why changing the primary endpoint "target" of a trial is considered a questionable research practice.

drugdevletter.com

Is One of the Most Popular Cardiac Drugs Better than its Generic Competitor?

The British Medical Journal has reignited a 14-year debate regarding the antiplatelet drug ticagrelor (Brilianta) and PLATO trial

open.substack.com

A Response to the NEJM's Sepsis Review Article

There's no test to "diagnose sepsis." What does that mean for clinical studies and health policy?

open.substack.com

The Petty/Bone RCT

When Hill published the first successful RCT in 1948 based on the teachings of Fisher, he spent considerable time presenting the need to test a treatment for a single disease. Pulmonary TB progresses...

discourse.datamethods.org

Scientific method: Statistical errors - Nature

P values, the 'gold standard' of statistical validity, are not as reliable as many scientists assume.

nature.com

Why I'm Thinking About Trees This Morning

A dark morning

open.substack.com

The Petty and Bone paradigm is dead

Once more, top critical care researchers will reaffirm the death of the Petty and Bone paradigm - and refuse to see it.

open.substack.com