🔬New research identifies a promising immunotherapy target for intrahepatic cholangiocarcinoma (iCCA). A new international study published in Signal Transduction and Targeted Therapy has identified MARCO as a promising therapeutic target in intrahepatic cholangiocarcinoma (iCCA).

🎥 Meet Bile-Bert! 💚 We're excited to launch Precision-BTC-Network Education, a new series of short educational videos on biliary tract cancer. Our first video introduces the basics of biliary stenting and its role in improving patient care. Read more below !👇

📅 Save the date: 29-30 April 2027 | 📍Salamanca (Spain) We are delighted to share that the next joint #ENSCCA / Precision-BTC-Network meeting will take place in Salamanca on 29-30 April 2027. This will be the final meeting of our #COSTaction and can't wait to see you all!

🔬New research from @precisionbtcnet.bsky.social sheds light on iCCA, a highly aggressive liver cancer. The study shows how tumour-derived IL-6 signalling reshapes cancer cells & the tumour microenvironment — revealing new metabolic vulnerabilities for therapy. 🔗 precision-btc.eu/news/114

📢 Registration & Call for Abstracts OPEN! Join the ENS-CCA / Precision-BTC Network Joint Conference! 📍Rhodes, Greece 🗓June 11–12, 2026 (in-person & online) 📝 Abstract deadline: 6 Apr 📋 Registration deadline: 6 May 🔗 Details & registration: precision-btc.eu/events/actio...

🔬 Upcoming Webinar: Translating HER2-Directed Therapy in BTC 🗓 Mar 2 | 🕒 15:00 CET | Online Part of the ICRN/ENS-CCA Translational Science Series. 🎙 Prof Joaquin Arribas & Dr Funda Meric-Bernstam 🎓 Chairs: Prof Juan Valle & Dr Anna Saborowski 🔗https://precision-btc.eu/events/webinars#

It’s #WorldCCADay! 🌍 We are proud to join the global #RecognizeCCA campaign to raise awareness for cholangiocarcinoma as a primary liver cancer. Watch our new video to see how Precision-BTC is working to advance research and improve outcomes for patients: 🧬📺 youtu.be/l2Tmw88Ib4E

Facing the Challenge if BTC in 2026 & Beyond | #WorldCCADay

YouTube video by Precision-BTC-Network

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Happy International Day of Women and Girls in Science!👩‍🔬 At Precision-BTC, women represent 54% of our 635+ members and hold 60% of our leadership roles. Our Gender Equality Plan ensures sex and gender equity are at the heart of both our research and governance🧬✨ Read more: precision-btc.eu/news/101

📣We are proud to announce the new International Consensus on CCA, now published in @natrevgastrohep.nature.com !🧬 This landmark update, led by @ENSCCA and @precisionbtcnet.bsky.social , provides a global roadmap for #CCA research and clinical care🌍 🔗 Read more: precision-btc.eu/news/99

📢 Supporting the next generation of BTC researchers! In our 3rd call we’ve awarded 12 grants (8 STSMs, 2 VM, 2 YRI) with 90% going to Young Researchers & 50% to ITCs 🌍 Plus, 45 trainees are joining our March Training Schools and 12 pairs have started the Mentoring Programme! 🚀

📢 Update: BTC Training School The “Biliary Tract Cancers: Practical Approaches in Challenging Environments” Training School has two key changes: 📍 New venue: Hospital Clínic de Barcelona 🗓️ Deadline extended: 3 Dec 2025 📋 Apply: docs.google.com/forms/d/e/1F...

📣 Upcoming Webinar! Join the next ICRN / Precision-BTC Network webinar on Translating HER2-Directed Therapy in Biliary Tract Cancer! 🗓️ December 9, 2025 ⏰ 09:00 ET / 15:00 CET Don't miss this expert discussion! cholangiocarcinoma-org.zoom.us/meeting/regi...

🚀3rd Call for Mobility Grants is OPEN! Apply now for STSMs, Virtual Mobility, or YRI Conference Grants — great chances to build skills, expand collaborations, and grow within the Precision-BTC Network. 🗓Deadlines: • STSM & VM: 20 Dic 2025 • YRI Grants: 20 Jul 2026

STSM highlight: meet Dr Bengi Ozkahraman 👋, who travelled from Turkey to London to work in the Faraday Lab at The Royal Institution under Prof Nguyễn T. K. Thanh. Her project focused on HA-modified liposomal Zn-doped iron oxide nanoflowers for targeted cisplatin delivery.

🧬 The new Multi-institutional BTC PDX Database is tackling one of the biggest gaps in BTC research, the lack of representative pre-clinical models. Led by Dr Anna Saborowski & Lisa Wende, it brings together PDXs and organoids from across Europe. 🔗 precision-btc.eu/news/80

Our next Virtual Mobility highlight: meet Gemma Iserte Fort 👋, Hepatic Oncology Advanced Practice Nurse at Hospital Clínic de Barcelona. Her VM project focused on how nurses across Europe can play a stronger role in cholangiocarcinoma care.

🌟 Deadline Extended! 🌟 There’s still time to apply for the @PrecisionBTCnet / @CcaEns / @curecc Mentorship Program — a unique opportunity to learn, connect & grow in BTC research. 🗓️ New deadline: Nov 7, 2025 👩‍🏫 Mentor: forms.gle/BtHBxxgtLxCT... 🧑‍🎓 Mentee: forms.gle/9we2jokL9pee...

Our next Mobility Grant highlight 🌍 Meet Esma Gökçe 👋, recipient of a Virtual Mobility Grant! Her project explored quality of life, anxiety, and depression in patients with cholangiocarcinoma through a prospective cohort study, aiming to improve patient-centred care.

📢Applications are OPEN for our next Training School! 'Biliary Tract Cancers: Practical Approaches in Challenging Environments.' 📍 Tbilisi, Georgia 🗓 March 21–22, 2026 Gain insights on BTC diagnosis, management & care centralization. 📋Apply by Nov 7 docs.google.com/forms/d/e/1F...

Our next STSM highlight: meet Kevin Delgado 👋, who joined Dr Luke Boulter’s lab at the University of Edinburgh. During his stay, Kevin explored 3D in vitro and in vivo models to study how tumour microenvironments contribute to chemoresistance in CCA.

📢Applications are OPEN for our upcoming Training School! Advanced Preclinical Models for Biliary Tract Cancers 📍University of Florence, Italy 🗓March 26–27, 2026 Gain hands-on experience with BTC models — from organoids to GEMMs. 📋Apply by Nov 4: forms.gle/ALfKSte3vArX...

🌟Calling all Young Researchers & Investigators! Applications are still open for our Mentorship Program — a chance to connect with experts, gain guidance & grow your career! 💬Past mentees: precision-btc.eu/post/alumni 📋Apply: precision-btc.eu/info/mentorp... 🗓Deadline: 1/11/2025

Precision-BTC-Network@precisionbtcnet.bsky.social · 10mo ago

Registration is OPEN for the 2025/26 Mentorship Program! The @precisionbtcnet.bsky.social/@CcaEns/@curecc initiative connects mentors & mentees worldwide to share knowledge, build skills & foster collaboration in BTC research. 🔗Info & registration precision-btc.eu/info/mentorp... 🗓Deadline 1 Nov

STSM highlight: meet Paraskevi Manoli👋, who travelled from the University of Patras 🇬🇷 to the University of Salamanca 🇪🇸 Her mission focused on evaluating BBR-based hybrid compounds in CCA cells, strengthening interdisciplinary collaboration across the Precision-BTC Network.

STSM highlight: meet @michelezanoni.bsky.social 👋, postdoctoral researcher at IRST Dino Amadori (Italy), who joined Dr Silvia Affò’s lab at IDIBAPS (Barcelona). His mission: developing advanced 3D and in vivo models of the iCCA TME to improve biological understanding and drug screening.

Our next STSM highlight: meet Jan Caira👋, PhD student from iMed (Lisbon) who joined Prof Jesús Banales’ group in San Sebastián. Her project explored the pharmacological activation of ferroptosis as a way to eliminate cholangiocarcinoma — from bioinformatics to in vitro assays.

Our next STSM highlight: meet Aynura Karimova 👋, who spent 2 weeks in Mannheim, Germany, working on iron oxide nanoparticles for cancer therapy. Her project explored how PEG & PEG/Tween 80 coatings can boost nanoparticle stability, drug loading & cytotoxicity.

Our next STSM highlight: meet Moyo Feyide 👋, who joined Prof Chiara Raggi’s team in Florence. He explored the use of 3D models to study primary liver cancers and deepened his understanding of metabolism in cholangiocarcinoma.

Registration is OPEN for the 2025/26 Mentorship Program! The @precisionbtcnet.bsky.social/@CcaEns/@curecc initiative connects mentors & mentees worldwide to share knowledge, build skills & foster collaboration in BTC research. 🔗Info & registration precision-btc.eu/info/mentorp... 🗓Deadline 1 Nov

Precision-BTC-Network@precisionbtcnet.bsky.social · 10mo ago

🌟New Mentorship Call Opens Oct 1🌟 The @precisionbtcnet.bsky.social Mentorship Program (with ENS-CCA & Cholangiocarcinoma Foundation) is back, connecting mentors & mentees to learn, share & grow! 🎥Watch highlights from last year’s edition youtu.be/5sJ8OYdMXPA Ready to join? Applications open soon!

Our next STSM highlight: meet Lisa Wende 👋, who joined Dr Tian Tian’s group at VHIO (Barcelona). She gained hands-on expertise with PDX & PDO models for cholangiocarcinoma — skills that will be key for her PhD project.

🌟New Mentorship Call Opens Oct 1🌟 The @precisionbtcnet.bsky.social Mentorship Program (with ENS-CCA & Cholangiocarcinoma Foundation) is back, connecting mentors & mentees to learn, share & grow! 🎥Watch highlights from last year’s edition youtu.be/5sJ8OYdMXPA Ready to join? Applications open soon!

Precision-BTC Network Mentorship Program | Growing Together

YouTube video by Precision-BTC-Network

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