Evaluating the impact of a sample-matched reference genome on single-cell transcriptomic inferences in Plasmodium falciparum #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.30.740912v1
#SingleCell preprints
@prepub-singlecell.bsky.social
feeds: biorxiv, medrxiv, arxiv.q-bio, arxiv.cs, arxiv.math, Research Square regex: '(single(- )(cell|nuclei)|s[cn]RNA-seq)' If you have suggestions, please get in contact with @willmacnair :)
DLC1 Downregulation Is Linked to Fibroblast-Stellate Matrix Programs and Malignant Phenotypes in Hepatocellular Carcinoma #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10242480/latest
Vascular Basement Membranes Establish a β2-Integrin-Dependent Macrophage-Preadipocyte Niche that Guides Adipose Tissue Fate #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10473265/latest
Interactions between single cellulose chain and water molecules and their temperature dependences: I. Pristine cellulose chain #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-9024787/latest
A 3D image atlas chronicling cellular and structural dynamics following lung injury identifies the aberrant expansion of endothelial cells that fail to form perfused vasculature #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10452545/latest
PlantNetX: A web-based transcriptomic resource integrating bulk and single-cell RNA-seq for plant functional genomics. #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.30.741827v1
Pharmacological up-regulation of CALM1 restore endothelial cells in intracranial aneurysm pathogenesis #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.08.04.742848v1
Clusterin regulates microglial inflammation and cognitive function independent of amyloid pathology in Alzheimer's disease #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.30.741791v1
Semi-automated annotation refinement accelerates cell type identification in brain spatial and single-cell studies #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.30.741795v1
Identifying the causal allele in the CD40 autoimmune locus enables discovery of context-specific trans-effects in B cells #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.29.741564v1
HER2 mutation-derived neoantigens in NSCLC as actionable targets for TCR therapy #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.30.741830v1
Tfh dysfunction underlies poor responses to HBV vaccination #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.30.741822v1
Making Single-Cell Data Distillation Auditable: Traceable Real-Cell Coresets via Discrete Min--Max Selection #SingleCell 🧪🧬🖥️ https://arxiv.org/abs/2607.19426
Scaling an Autoregressive Transformer for Single-Cell Generation #SingleCell 🧪🧬🖥️ https://arxiv.org/abs/2608.02961
Epithelial-Intrinsic Alterations and Maladaptation to Luminal Metabolites Underlie Persistent Crohn's Disease Pathogenesis #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.29.741535v1
IFNγ and proinflammatory cytokines cooperatively license astrocytes to support antigen-dependent CD4+ T cell restimulation #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.29.741554v1
Single-cell transcriptomics reveals a multiphasic Wolbachia host infection trajectory #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.29.741357v1
Multidirectional Cellular Plasticity in Ewing Sarcoma Reveals a Tumor-CAF Continuum and Novel Immunotherapeutic Targets #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.08.03.742600v1
Fluctuating environment causes neoplastic transition and epithelial-mesenchymal plasticity in human cells #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10094171/latest
Single-cell foundation models predict durable CAR T response despite imperfect cell annotation #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10412263/latest
Malignant B-cell States Orchestrate Spatially Organized Immune Ecosystems in B-cell Lymphomas #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10435263/latest
An AI-Mechanistic Coagulation–Cardiovascular Framework for Reducing Arrhythmia Risk Under Vascular Stress #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10545064/latest
Evaluating in vitro spermatogenesis in Atlantic salmon using single-cell transcriptomics #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.08.04.742726v1
An AI-Mechanistic Coagulation–Cardiovascular Framework for Reducing Arrhythmia Risk Under Vascular Stress #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10545064/latest
LiteVax-adjuvanted influenza vaccine induces transient interferon-driven innate activation and accelerates early IgG3 responses in older adults #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10356158/latest
Dissecting the Immunosuppressive Tumor Microenvironment and Intercellular Communication in Testicular DLBCL via scRNA-seq #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10237867/latest
A benchmarking framework for single-cell genome-scale metabolic model construction #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.08.02.742346v1
Inflammatory Fibroblasts Promote Repair After Injury Through Epithelial Proliferation #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.08.02.742235v1
Longitudinal single cell RNA-sequencing of Pik3caH1047R-driven mammary tumorigenesis reveals coordinated transformation of epithelial and fibroblast transcriptional states #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.08.01.742267v1
Comprehensive profiling of Tubby-like protein in grapevine and the functional role of VamTLP1 in cold stress response #SingleCell 🧪🧬🖥️ https://www.researchsquare.com/article/rs-10366232/latest