Hey y’all, New paper out from the lab in Microbial Genomics, starting down the rabbit hole of IS elements in Paeudomonas syringae www.microbiologyresearch.org/content/jour...

Independent, ongoing clade-specific expansions of IS5 elements in Pseudomonas syringae

Insertion sequence (IS) elements are transposable regions of DNA present in a majority of bacterial genomes. It is hypothesized that differences in distributions of IS elements across bacterial strain...

microbiologyresearch.org

MENI is back! Join us in Dublin this August 2026 for our 3rd Meeting for Microbial Evolution in Ireland. We are delighted to have @rachelmwheatley.bsky.social @drrebeccajhall.bsky.social @jpjhall.bsky.social and @tweethinking.bsky.social join us as keynote speakers this year. miniurl.com/MENI

Shite database shite output. Level of interpretation of output can lead to torrent of shite.

Our new paper in MGen traces the evolution of a plasmid lineage associated with MDR in Enterococcus faecium, primarily driven by IS1216 For anyone interested in plasmid structures and the smaller MGEs that shape them 🧵👇 [1/14] @microbiologysociety.org www.microbiologyresearch.org/content/jour...

IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium

pRUM-like plasmids are commonly found in multidrug-resistant Enterococcus faecium, but the evolution of these plasmids has not been characterised in detail. When we analysed the genome sequences of tw...

microbiologyresearch.org

The first preprint from @izziepotterill.bsky.social PhD. A clone within ST131 clade C with a totally unique capsule region.

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · 8mo ago

Genomic rearrangement of the capsule operon in a phylogenetically distinct cluster of the multi-drug resistant Escherichia coli lineage ST131 https://www.biorxiv.org/content/10.64898/2025.12.15.689991v1

Maybe I am being grumpy, but can people please stop using poorly curated databases of antibiotic resistance genes (I am looking at you, DeepARG) on shotgun metagenomic data and then present these results without any reflection on their validity, or shortcomings of databases?

Happy Noodlococcus day to all those who celebrate! 🍜🧫🦠 We’re in 3 different continents now but all celebrating the 6th anniversary of the discovery of our noodle-y friend by eating some delicious noodles @prob91.bsky.social @biostan.bsky.social @gemccallum.bsky.social

🚨New pre-print 🚨 We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n www.biorxiv.org/content/10.1...

Genome co-adaptation and the evolution of methicillin resistant Staphylococcus aureus (MRSA)

Background: Antimicrobial resistance (AMR) in bacterial pathogens is a major threat to global health, rendering standard treatments ineffective and increasing the risk of severe infection or death. Re...

biorxiv.org

New manuscript from the group 'IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium' www.biorxiv.org/content/10.1... /1

IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium

pRUM-like plasmids are commonly found in multidrug-resistant Enterococcus faecium , but the evolution of these plasmids has not been characterised in detail. When we analysed the genome sequences of t...

biorxiv.org