Can acute kidney injury have long-term consequences? Even when kidney function appears to recover, inflammation, incomplete tissue repair, or fibrosis may persist and increase the risk of CKD. #AKI #CKD #KidneyResearch #Biomarkers #PICKEDproject

Why are urine samples so valuable in kidney research? They can be collected non-invasively, repeatedly, and contain peptides, proteins and other molecular signals linked to kidney damage, inflammation and treatment response. #KidneyResearch #Biomarkers #Peptidomics

Doctoral Candidate Julia Byrska presented her research on urinary peptide biomarkers for the non-invasive diagnosis of Alport syndrome at the 8th Cardiovascular, Renal and Metabolic Diseases Area Meeting. Read more: 🔗 www.projectpicked.eu/news-and-eve... #KidneyResearch #AlportSyndrome #Biomarkers

What is kidney reserve? Healthy nephrons can compensate for early kidney damage, keeping eGFR normal even while disease progresses. This is why researchers are developing biomarkers to detect damage earlier and improve personalised care. #KidneyHealth #CKD #Biomarkers #EarlyDetection

The PICKED Doctoral Candidates have launched a peer-led Journal Club to discuss recent research, exchange ideas, and strengthen collaboration across Europe. Read more: 🔗 www.projectpicked.eu/news-and-eve... #PICKEDproject #MSCA #KidneyResearch #JournalClub #HorizonEurope

Why can albuminuria appear before eGFR falls? Kidney damage often starts before eGFR declines. Albuminuria, small amounts of albumin in urine, can be an early sign that the kidney's filtration barrier is already under stress. #CKD #Albuminuria #KidneyHealth #PrecisionMedicine #PICKEDproject

PICKED Doctoral Candidate Jeremy Power presented at a UNESCO Chair symposium in Toulouse on how AI is reshaping personalised medicine from a clinical ethics perspective. 📖 Read more: www.projectpicked.eu/news-and-eve... #PICKEDproject #AI #PersonalisedMedicine #ClinicalEthics

New PICKED-related publication in NDT 🔬 Julia Byrska and colleagues explore how biological age, estimated from remaining life expectancy, may help explain the burden of kidney failure beyond chronological age alone. 📖 Read more: academic.oup.com/ndt/article-... #CKD #KidneyResearch #Nephrology

The burden of kidney failure requiring kidney replacement therapy explained by estimating biological age from remaining life expectancy

To the Editor,

academic.oup.com

CKD often develops silently. Early detection can help identify kidney disease before major damage occurs, allowing earlier treatment and better prediction of progression. That means fewer complications and better outcomes for patients. #CKD #EarlyDetection #KidneyHealth #PICKEDproject

Two patients can have the same kidney disease but respond very differently to the same treatment. Why? CKD is biologically diverse. Personalised medicine aims to match treatment to the patient, not just the diagnosis. #CKD #PrecisionMedicine #PICKEDproject

Kidney fibrosis is the build-up of scar tissue after kidney injury. Over time, it can reduce kidney function and drive CKD progression. By detecting fibrosis-related changes earlier, biomarkers may help predict outcomes and support treatments targeting the underlying biology. #CKD #KidneyFibrosis

Kidney disease and heart disease are closely connected. CKD increases cardiovascular risk, while heart disease can damage the kidneys. Understanding these links is key to personalised medicine. #CKD #CardiovascularDisease #PICKEDproject

🔬 DC Sheila Murunga presented her work on biomarker-based risk prediction and biological stratification in pediatric CKD at the ESCAPE Network Meeting (11–12 June 2026, Heidelberg). 📖 Read more: www.projectpicked.eu/news-and-eve... #CKD #KidneyResearch #PrecisionMedicine #ESCAPENetwork

CKD is not one-size-fits-all. Patients may share similar kidney numbers, but differ in causes, risks, biology, symptoms, and treatment response. Personalised medicine aims to make kidney care more precise, targeted, and patient-centred. #CKD #PersonalisedMedicine #PICKEDproject

PICKED at ERA 2026 in Glasgow 🔬 Julia Byrska and Abukayo M will present their work through oral and poster presentations at the 63rd ERA Congress. Great to see PICKED research represented at ERA! #ERA2026 #CKD #PICKEDproject #KidneyResearch

#Delta4's Enrico presented his poster at the #YSA Symposium 2026 at the Medical University of Vienna. His work on systems-biological modeling of the #AKI-to-#CKD transition was selected for Session V (Regeneration & Transplantation) and sparked lively scientific discussion. #TranslationalResearch

Urine can tell us more than standard kidney markers alone. Peptidomics studies small protein fragments in urine that may reflect tissue damage, inflammation, fibrosis, progression, or treatment response. Another layer for more personalised CKD care. #CKD #Peptidomics #PICKEDproject

In CKD, “high risk” is not just one kidney function number. Two patients can have the same eGFR but very different outlooks depending on albuminuria, blood pressure, diabetes, biomarkers, genetics, and disease history. Better risk prediction means better timing and care. #CKD #PICKEDproject

A promising biomarker is only the beginning. Before it can guide patient care, it must be validated across cohorts, labs, and real clinical settings. That takes time, and it should. Validation protects patients and turns research into real impact. #CKD #Biomarkers #PICKEDproject

Kidney research does not automatically become better patient care. Between discovery and real-world use lies the implementation gap: validation, regulation, reimbursement, data protection, workflows, and proof of impact. Closing that gap is how research becomes real benefit. #CKD #PICKEDproject

Uremic toxins are more than urea. In CKD, different toxins can accumulate, some easier to remove, others harder and linked to inflammation, symptoms, or cardiovascular risk. Personalised kidney care means looking beyond one number. #CKD #KidneyHealth #PICKEDproject

PICKED at the ERKNet Annual Meeting 2026 in Lyon, with Jeremy Power and Sheila Murunga representing their work within the project. A valuable opportunity for exchange, networking, and connecting personalised kidney care research with the rare kidney disease community. #PICKEDproject #ERKNet #CKD

CKD care can’t be only lab numbers (eGFR, creatinine, K+). Two patients with similar labs can feel very different, fatigue, itch, sleep issues, cramps, brain fog, mood. QoL is a core outcome: track symptoms + shared decisions. #CKD #KidneyHealth #PICKEDproject

DC Spotlight 🌟 Enrico Bono: building a network-based in silico model of the AKI→CKD transition to prioritise biomarkers/targets and identify drug repurposing opportunities. Read: www.projectpicked.eu/news-and-eve... #PICKEDproject #AKI #CKD #SystemsBiology

Endothelial dysfunction = the blood vessel lining stops working well (↓ vasodilation, ↑ permeability/inflammation/clotting). In CKD this helps explain why kidney risk and cardiovascular risk travel together, often reflected by albuminuria too. #CKD #KidneyHealth #PICKEDproject

Creatinine can mislead. Muscle mass, meat/creatine, exercise, dehydration, and some meds can shift it without true GFR change. Look at trends + uACR (± cystatin C). #CKD #KidneyHealth #PICKEDproject

DC Spotlight 🌟 Sheila Murunga (PICKED): recruiting & collecting samples for the validation cohort, strengthening findings from the 4C cohort and moving toward biological stratification in paediatric CKD. Read: www.projectpicked.eu/news-and-eve... #PICKEDproject #CKD #Biomarkers

Hematuria = blood in urine, but where it comes from matters. Glomerular (kidney filter) → dysmorphic red blood cells (RBCs) / RBC casts. Urologic (downstream) → round, normal RBCs. Microscopy adds meaning. #CKD #Hematuria #KidneyHealth #PICKEDproject

How do we protect patient data in personalised medicine, not just today, but in 10 years? 🔒 Privacy by design: minimise data, limit purpose, pseudonymise + control access, secure by default, be transparent. And yes, plan for a post-quantum future. #PICKEDproject #DataProtection #PrivacyByDesign

What does “early detection” mean in CKD? Not symptoms, molecular/structural damage starts first. That’s why simple routine checks (eGFR + albuminuria) + biomarkers matter: detect risk early, act sooner. #CKD #KidneyHealth #EarlyDetection #PICKEDproject