Structure of PCPE-2 in complex with the BMP-1 metalloprotease reveals the molecular basis of its mechanism of inhibition https://www.biorxiv.org/content/10.64898/2026.09.22.752281v1

Linking HLA class II susceptibility to HSPC transcriptomics and antigen presentation in aplastic anemia https://pubmed.ncbi.nlm.nih.gov/42774213/

How conformational dynamics shape hydrogen-deuterium exchange isotopic envelopes https://pubmed.ncbi.nlm.nih.gov/42770763/

Beyond the Generic Tumor: Engineering Patient-Specific Immune Ecosystems for Cancer https://pubmed.ncbi.nlm.nih.gov/42764098/

Structural Basis for Activation of HRI by the DELE1 C-terminal domain https://www.biorxiv.org/content/10.64898/2026.09.15.751698v1

A Practical Workflow for Reliable MALDI-Based Hydrogen/Deuterium Exchange Mass Spectrometry https://pubmed.ncbi.nlm.nih.gov/42761390/

Ara h 2 and FcϵRIα binding elicit state-dependent allostery in IgE https://www.biorxiv.org/content/10.64898/2026.09.11.750994v1

Cancers modulate processing and presentation of p53 neoantigens to evade T cell detection https://pubmed.ncbi.nlm.nih.gov/42753739/

Structural Characterization of Calcium-Dependent Calmodulin-Calmidazolium Binding Using Capillary Vibrating Sharp-Edge Spray Ionization-Based Native Mass Spectrometry and In-Droplet Hydrogen-Deuterium Exchange Mass Spectrometry https://pubmed.ncbi.nlm.nih.gov/42757150/

Immunopeptidomics-driven MHC class II peptide-binding motif discovery for 2 common canine DR alleles https://pubmed.ncbi.nlm.nih.gov/42752862/

Oncogenic fusions induce an extensive cancer-restricted cryptic proteome in Ewing sarcoma https://www.biorxiv.org/content/10.64898/2026.09.16.751792v1

Immunopeptidomics-guided cancer vaccine design: Advances, challenges, and emerging opportunities https://pubmed.ncbi.nlm.nih.gov/42743775/

Therapeutic cancer vaccines: development, challenges, and future perspectives https://pubmed.ncbi.nlm.nih.gov/42736453/

Impact of the functional ERAP2 rs2248374 polymorphism on the HLA class I immunopeptidome in primary human epidermal keratinocytes https://pubmed.ncbi.nlm.nih.gov/42735508/

HDX-MS-Guided computational modeling for rapid and accurate antibody-antigen interface mapping https://pubmed.ncbi.nlm.nih.gov/42725674/

A peptidomimetic inhibitor blocks Vibrio cholerae adhesin FrhA. https://www.biorxiv.org/content/10.64898/2026.09.07.749730v1

Discovery of CD4+ T cell-recognized B. pertussis antigens that reduce airway colonization https://pubmed.ncbi.nlm.nih.gov/42708360/

Understanding HLA risk in immune-mediated inflammatory diseases requires antigen discovery https://pubmed.ncbi.nlm.nih.gov/42705941/

ExchangeXplorer: an R/Shiny application for processing and visualization of LC-HDX-MS data in metabolomics, lipidomics, and exposomics https://pubmed.ncbi.nlm.nih.gov/42702477/

Immunopeptidomics in gliomas: Decoding antigen presentation for precision immunotherapy https://pubmed.ncbi.nlm.nih.gov/42697339/

Mass Spectrometry-Based Profiling of Personalized Immunopeptidomes in Thai Renal Cell Carcinoma https://pubmed.ncbi.nlm.nih.gov/42695889/

HLA-II peptide-binding diversity shapes humoral immune responses and susceptibility to infections https://pubmed.ncbi.nlm.nih.gov/42686785/

Cryo-EM Structure of a Triazole alpha-Conotoxin GI Mimetic Bound to the Muscle-Type Nicotinic Acetylcholine Receptor https://www.biorxiv.org/content/10.64898/2026.08.31.748223v1

Normal-immunopeptidome denominator: a safety atlas for immunotherapies targeting non-canonical and aberrantly expressed tumor antigens https://pubmed.ncbi.nlm.nih.gov/42680204/

Mapping Light-Induced Conformational Dynamics of Pigeon Cryptochrome 4 by HDX-MS: Structural Transitions from Spin Pair Formation to Activated Conformational States https://www.biorxiv.org/content/10.64898/2026.08.27.747556v1

Systematic Workflow Optimization for Ultra-sensitive Targeted Immunopeptidomics https://pubmed.ncbi.nlm.nih.gov/42551630/

LemonCatcher Acidic Pull-Down Enables Selective In-Cell Hydrogen-Deuterium Exchange Mass Spectrometry https://www.biorxiv.org/content/10.64898/2026.08.26.747387v1

Fusion-derived phospho-neoepitopes define a prioritized candidate neoantigen repertoire in MASLD-HCC https://www.biorxiv.org/content/10.64898/2026.08.26.747243v1

Phosphorylation shapes antigen presentation and immune recognition: mechanistic insights and translational perspectives https://pubmed.ncbi.nlm.nih.gov/42657027/

Skewed MHC Class I Peptide Presentation in Psoriatic Arthritis https://pubmed.ncbi.nlm.nih.gov/42653321/