Paul Thompson
@ptenigma.bsky.social
Neuroscientist, professor AI guided tour - https://www.youtube.com/watch?v=fOORfzGjCTA ENIGMA guided tour - https://www.youtube.com/watch?v=YNjP5nZsJyQ Diffusion MRI of Brain Diseases - https://www.youtube.com/watch?v=i2jHFm0wcN0
Amazing win by Harri and Henry in the Wimbledon men’s final. Apparently there is another England Scandinavia game in 2 hours ? :) 🇳🇴🏴
No way 🏴England 2 🇲🇽Mexico 1 @ half time. ... #FIFAWorldCup #FIFA #WorldCup
2 weeks ago at OHBM, great opportunity to speak French, parce que c'est l'occasion. Thanked Hervé for finding us a great ENIGMA venue. Taxi driver helped pronounce it better. French is more compact than English, a sign read: "Tout abus sera puni". can't be said in another language in 16 letters? :)
The OHBM conference (Bordeaux) was a great opportunity to speak French, parce que c'est l'occasion. I thanked Hervé for finding us a great venue. Taxi driver helped me to pronouce it better. +Look at its very high compression: "Tout abus sera puni". Cannot be said in another language in 16 letters?
🔥Optimizing the future rate of discovery using the zeta law [1] + future-optimized encoders* *maybe it would be easier to just bet on the World Cup [1] arxiv.org/pdf/2604.17581 sequel coming next week
Almost there * *the rental car man at Manchester airport said “are you going to drive far”
You can tell England has scored without watching the TV as there is basically yelling that is correlated with something good happening
People here basically start eating their tea at 1030pm as it’s so hot
🔥 100°F+ ENIGMA PARTY @OHBM2026, Bordeaux. 🔥What a night! Thanks to everyone* who joined us+1000000 thanks to Sophia Thomopoulos for organising 🔥 🔥 *Pictured, Row 1: PT, Katharina Wittfeld, Sven Cichon, Alexander Teumer, Thomas Müliesen; Clara Moreau, Johanna Bayer, Lune Bellec, Andrei Irimia, ..👇
As the World Cup is starting, you are probably wondering if it is possible to make a Hamiltonian path that traverses all nodes+ edges of a soccer ball only once but returns to its initial position.* If you see anyone playing soccer, you should stop the game and ask them this. *Bonus puzzle below...
🔥 NEW VIDEO discussion of current research in Alzheimer's, Parkinson's, schizophrenia, bipolar disorder, depression, autism, ADHD; tune in here: 🔥 Part 1 www.youtube.com/watch?v=N7YB... 🔥 Part 2 www.youtube.com/watch?v=RHmr...
New multicohort study (N=1,965) finds maternal metabolic health may shape early brain development in sex-specific ways. rdcu.be/flutX @enigmabrains.bsky.social @ptenigma.bsky.social
Infant subcortical brain volumes associated with maternal obesity and diabetes: a large multicohort human study
rdcu.be
1⃣On average, FA reached maturity at the youngest age (mean=29.2 years), followed in order by RD (mean=35.8 years), MD (mean=41.7 years) and AD (mean=48.2 years). We found evidence supporting the ‘last-in, first-out’ hypothesis, for FA, MD and AD.
We present the LARGEST normative model of the brain’s white matter microstructure: 54,583 subjects, 4-91 yrs, 19 datasets. We derived lifespan centile curves for DTI FA, MD, RD, AD, detecting anomalies for dementia, and Mild Cognitive Impairment: doi.org/10.1038/s414... ⤵️
COME JOIN US: Çağdaş Eker will give an incredible talk Thursday at the Marina. DM me if you want to come. A world-renowned expert on bipolar disorder, he will review the common and shared brain circuitry with major depressive disorder, differential diagnosis, and treatment effects.
🔥OK the percolation app should work on your phone ! ptenigma.github.io/percolation-... (try it!) 🔥This is basically what happens when your AI model is learning to generalise from N training samples, and you feed it more data :)
🔥DOES ANYONE KNOW how we can link to an animation or a fun little app with widgets in an anonymised paper, without it being obvious who made the app? 🔥We want to put a little app in our paper on percolation+generalisation in deep learning, so people can play with it/develop their intuition
🔥 1000000 congrats to Wendy (Yixue) Feng +all today's amazing graduates!! 🔥 Wendy's PhD thesis* "Advanced Statistical+Deep Learning Methods for Diffusion MRI Tractometry" is on 🔥 detecting Alzheimer's w/ "generative tractometry"+ boosting tractography's sensitivity to brain diseases *links below
I should be working on a grant but am obsessing a bit about this problem, on the links between D-dimensional percolation and sample complexity (how much data we need to train an AI model with latent space embedding dimension D).
🔥 🧠 Some fun Riemann zeta function spirals for my talk on cross-over* and model capacity in deep learning *i.e. when will one deep learning model start to outperform another [1], and how to speed up the future rate of discovery [1] arxiv.org/abs/2604.17581
I found this wonderful review of a paper I submitted in 1997! Especially fun as these reviews used to arrive from the journal via FAX machine and they would call you to tell you to turn it on so it could be sent through
