So proud to be part of these studies and advance #GeneEditing therapies for #SCD and #TDT by editing gamma globin promoters and mimic nature like persistent feral haemoglobin. Thanks 🙏 for patients , research team @clevelandclinic.bsky.soci and great team of investigators 👏🎉

Waggoner Lab@labwaggoner.bsky.social · 6mo ago

www.nejm.org/doi/full/10.... www.nejm.org/doi/full/10.... www.nejm.org/doi/full/10.... @harvardmed.bsky.social @clevelandclinic.bsky.social @drheeney.bsky.social @hfrangoul.bsky.social @rabihannamd.bsky.social

so honored and excited tos hare on behalf of all our team and co-investigators the results of RUBY study #EditasMedicine that used novel first-in human CRISPR-Cas12a Gene Editing of HBG1 & HBG2 Promoters to treat #SickleCell Disease which was published today in @nejm.org www.nejm.org/doi/full/10....

#ASH25 #bmtsm Soiffer: although cGVHD reduced overall, this benefit of cryo was not seen in pts getting PTCy. Given higher OS in spite of lower GRFS with cryo, fresh grafts remain the preferred standard (but still reasonable when logistically useful).

Dr. Lucy Fox for outstanding talk at #LBA #ASH25 Whole Genome Sequencing upfront in large cohort of adult & pediatric pts with suspected IBMFS found high diagnostic rate (37.1%) - cost is ~8100 $ but expected to 📉 - impact on patient counselling & therapy - new discoveries

Grateful for the wonderful ‘You Have Been ASH’d experience ✨. WE are the ones who should be thanking @ash.hematology.org for bringing us together, building community, and inspiring the next generation of trainees 🙌. Hem is simply the best — a family and a field that inspires us every day ❤️ #ASH25”

It’s always inspiring to meet global colleagues, mentors, and mentees at the #ASH25 meeting. Medicine is the ultimate team sport — we learn, grow, and advance together. Grateful to @ash.hematology.org for fostering a truly global hematology community. 🌍🩸

#ASH25 #bmtsm Kuball: no strong evidence for different outcomes using frozen G mobilized DLI (ie, leftover from graft collection) vs fresh steady state collection.

Dr. Lachelle Weeks presented interesting data about #CHIP present in #SCD patient and I am surprised to see it as early in childhood (up to 7% by age 11) and how the incidence increases. It was not observed in sickle trait. Unknown are the implications for 🧬 #GeneTherapy #ASH25

Congratulations 🎉👏 Dr. Crawford Strunk @clevelandclinic.bsky.social for a powerful #ASH25 presentation on integrating palliative care into SCD management. Inspiring to see how this approach not only enhances patient well-being but also improves length of stay #SickleCell

🚀 Calling all ASH trainees! This is your chance to shape the future of hematology. Join the ASH Trainee Council and amplify your voice, your ideas, and your impact. Scan the code below and apply today! 🌟 #ASH25 #HemeTrainees #Leadership

Grateful for the opportunity to join #BloodBuddies at #ASHApalooza #ASH25 @ash.hematology.org ‬⁩ Fast-paced mentorship, big ideas, and even bigger passion from trainees — truly energizing. I also learn from them more than they know- it is like highway /knowledge flows both ways

Excited to participate in #ASH-a-palooza at #AS25 #BLOODBUDDIES Designed for undergraduates, medical and graduate students, residents, and fellows, ASH-a-Palooza provides a variety of opportunities for trainees attending @ash.hematology.org meeting #ASH25 youtu.be/aVAJg-qp99Y

ASH-a-Palooza

YouTube video by American Society of Hematology

youtu.be

How immuniry change wuth age - age-dependent TH2 bias in CD4 T cells and CD8 T cells is broadly driven by reduction in T cell signalling strength over time www.nature.com/articles/s41...

Multi-omic profiling reveals age-related immune dynamics in healthy adults - Nature

This multi-omic longitudinal analysis of the healthy human peripheral immune system constructs the Human Immune Health Atlas and assembles data on immune cell composition and state changes w...

nature.com

Grateful to our amazing @CleClinic_PHO team for shining so brightly at #LightTheNight 🌟 Your passion and advocacy bring hope to leukemia & lymphoma patients and families every day. Together, we’re lighting the path toward a cure. ❤️🕯️ #LLS #TeamClevelandClinic @bloodcancerunited.bsky.social

You want to feel good and 🤩👏… come to @velosano . Nothing feels as good as being with previous #ChildhoodCancer patients who are now #Survivors and #riding for the #Cure

Here we go ; safe ride to all #Riders @bikeVeloSano 25 miles. 🙏thank you so much for all you do to raise $ for #CancerResearch at @ClevelandClinic 💯 for the #Cure . Cancer impact goes beyond one patient , one family … it affects the community and together 💪 can make an impact

The impact of CMV reactivation on mortality after chimeric antigen receptor T-cell therapy url: ashpublications.org/bloodadvance...

The impact of CMV reactivation on mortality after chimeric antigen receptor T-cell therapy

TO THE EDITOR:

ashpublications.org

Join us on July 26 at the Cleveland Metroparks Zoo for a one-of-a-kind bike ride for kids ages 3–10 to raise funds for pediatric #cancer #research at @clevelandclinic.bsky.social . www.velosano.org/trike-bike www.velosano.org/trike-bike/

Trike & Bike | VeloSano

Kids can help fight pediatric cancer with Trike & Bike. Join community bike rides supporting Cleveland Clinic Children’s. 100% of funds go to research.

velosano.org

This is sad news abd huge loss to #Medicine #Pediatric and #Science in general . May his menory be a blessing . pioneerpressobits.space/atul-butte-s...

Atul Butte San Francisco, CA Obituary, American pediatrician and UCSF professor Atul Janardhan Butte Dies From Cancer - Pioneer

Dr. Atul Janardhan Butte, San Francisco, CA Obituary, Death: The vibrant San Francisco and global scientific communities mourn the loss of Dr. Atul Janardhan Butte, 55, who passed away on June 13, 202...

pioneerpressobits.space

Mentorship is a powerful way to give back in #PedsHemOnc. I am so honored to be among #mentors at the American society of pediatric hematology - oncology speedy mentorship supporting the next generation boosts career satisfaction, fosters personal growth & strengthens our field for the future.

Dr. Caitlyn Duffy from @stjude.bsky.social presented great talk at poem_group about Implementation science in leukemia 1- discussed the 17 year odessy - translation of discovery to delivery 2- EPIS implementation framework

So grateful to be invited to #POEM 4th Scientific Conference! Connecting with ped oncologists to improve care & access for kids with cancer has been truly inspiring. 👏🎉 Dr. rawad rihani and Dr. Gevory Tamamyan for fantastic reception to start #POEM2025 #PediatricOncology #CancerCare

open.spotify.com/episode/4SnN...

Finding the Words: Talking Cancer with Children

Little Health: A Cleveland Clinic Children’s Podcast · Episode

open.spotify.com

A heartfelt thank you to our incredible team at Cleveland Clinic Children’s for coming together in support of St. Baldrick’s Foundation. Your dedication, generosity, and passion for making a difference in the lives of children with cancer is truly inspiring #StBaldricks m.youtube.com/watch?v=azNy...

St. Baldrick's Foundation foundation hosts head shaving event, raises money for kids with cancer

The St. Baldrick's Foundation hosted a fundraising event for kids with cancer Sunday afternoon.

m.youtube.com

Thank you 👏 Dr. Jim Fernandez for organising great conference #PrimaryImmunodeficiency at @ClevelandClinic and great talk about #IVIG . It is amazing to see the use increase significantly. Did you know it takes 8-9 months to make IVIG and it approximately collected from 15,000 donors

Great advice by Troy Torgerson about what to do when you have VUS “variable unknown significance “ at @clevelandclinic.bsky.social #PrimaryImmuneDeficiency symposium

Still time to join us at #UodateInPrimaryImmunodeficiency at @clevelandclinic.bsky.social endorsed by immune deficiency foundation Very educational agenda and world renowned experts discussing diagnosis and management of different immune deficiencies www.clevelandclinicmeded.com/live/courses...

Join us for the inaugural Updates in Primary Immunodeficiency CME symposium. This course provides an educational forum for faculty to deliver in-depth reviews of common and rare inborn errors of immunity (IEI), a group of more than 400 complex, chronic disorders.

clevelandclinicmeded.com

Celebrating a Second Chance at Life Symposium May 3 - 9, 2025 A week packed full of information, inspiration and community. symposium.bmtinfonet.org

The fight against # ChildhhodCancer is not just medical challenge - it is calling - beyond medication to wholistic care So proud of our music therapist 🎉👏 Emily Ervin @CleClinicKids for supporting kids - see picture below 👇 with one of our kids cutting her hair

So proud and inspired by our team : Preston , Katie and Stacey participating in @clevelandclinic.bsky.social #StBaldrick shave for the cure event We are doing what we do to support kids & their families and organisations like St Baldrick so we can do research to find more cure and better therapies