I am excited to share a lab publication, led by former postdoctoral fellows Daniel Benjamin and Jengmin Kang, examining how quiescent stem cells allocate resources for survival over function during aging and revealing a survivorship bias in the study of cell aging. www.science.org/doi/10.1126/...

Cellular survivorship bias as a mechanistic driver of muscle stem cell aging

Aging is characterized by a decline in the ability of tissue repair and regeneration after injury. In skeletal muscle, this decline is largely driven by impaired function of muscle stem cells (MuSCs) ...

science.org

We’re delighted to welcome Future Science Prize 2024 winner Hongkui Deng @pku1898.bsky.social to the speaker lineup at the upcoming @CellSymposia #CSStemCells2025. Submit an abstract for a chance to join him in LA in November! http://dlvr.it/TLn6XX

This study represents the next stage of organoid development, incorporating vascularization. #stemcellresearch #regenerativemedicine

UCLA Broad Stem Cell Research Center@uclastemcell.bsky.social · last yr.

Scientists have created the first 3D mini-lungs complete with their own functioning blood vessel networks, unlocking new insights for pulmonary vascular disease. ➡️ bit.ly/4kmCrxB #Organoids #LungOrganoids #StemCellResearch

Happy to share our review at Cell Stem Cell as part of their Hallmarks series. As always, a pleasure to work with friends and colleagues Anne Brunet (@brunetlab.bsky.social) and Peggy Goodell(@goodell-lab.bsky.social). Hallmarks of stem cell aging: Cell Stem Cell www.cell.com/cell-stem-ce...

Hallmarks of stem cell aging

Aging disrupts core functions of somatic stem cells throughout the body, leading to impaired tissue maintenance and repair. We identify five key features of aged stem cells, highlighting how their dys...

cell.com

UCLA’s Translational Cell Therapy Lab partners with stem cell researchers to build life-changing therapies — all while mentoring the next generation scientists who’ll carry this critical work forward. 🧬 Read more: ucla.in/45kYAbz #CellTherapy #RegenerativeMedicine

A new twist for SSRIs - potential role as adjuncts for cancer therapy thanks to the pioneering work of Dr. Lili Yang.

UCLA Broad Stem Cell Research Center@uclastemcell.bsky.social · last yr.

A UCLA study suggests that common antidepressants could enhance the immune system’s ability to fight #cancer and suppress tumor growth. Repurposing these existing FDA-approved drugs could speed up the process of bringing new cancer treatments to patients. stemcell.ucla.edu/news/common-...

Another life-saving treatment from Dr. Donald Kohn's group at UCLA and collaborators. Congratulations to the incredible team of investigators. Another milestone for the miracles of cell and gene therapy.

UCLA Broad Stem Cell Research Center@uclastemcell.bsky.social · last yr.

A new study in @nejm.org reports that an investigational gene therapy restored immune function in 9 children with LAD-I, a rare & life-threatening immune disorder. Those children are now living symptom-free 2 years after treatment in clinical trials co-led by Dr. Donald Kohn at UCLA.

I am excited to share a recent publication from the lab, spearheaded by senior scientist Di Wu, using a bioinstructive nanocapsules to orchestrate the temporal delivery of growth factors in order to promote stem cell-mediated tissue engineering in vivo. www.nature.com/articles/s41...

Bioinstructive scaffolds enhance stem cell engraftment for functional tissue regeneration - Nature Materials

A decellularized extracellular matrix scaffold containing nanocapsules orchestrates timed growth factor release to promote muscle stem cell proliferation and differentiation and effective muscle regen...

nature.com