Rick Lanman

@ricklanman.bsky.social

Interests are historical ecology (mostly California), cancer, genomics, CoViD, and genealogy.

Respiratory infections like CoViD & flu awaken metastatic breast cancer lesions so they start growing rapidly. Wearing a mask in crowded places like airports, church, buses makes good sense - remember the main reason to mask is to protect the vulnerable from ourselves www.nature.com/articles/s41...

Respiratory viral infections awaken metastatic breast cancer cells in lungs - Nature

Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by epidemiological d...

nature.com

Cannabis Use Disorder associated with a tripling of oral cancer in 5-year study at six Univ. of California academic centers. Smoking cannabis or tobacco similarly damage the mouth's lining. Not all that new - just strongly confirms the earlier reports of risk. www.sciencedirect.com/science/arti...

Cannabis use disorder and five-year risk of oral cancer in a multicenter clinical cohort

Cannabis use disorder (CUD) is increasingly prevalent in the United States, yet long-term health consequences remain poorly defined. Oral cancer is pl…

sciencedirect.com

So tragic. Children living downstream from nuclear waste storage site on Coldwater Creek near St. Louis, had 5x greater risk of thyroid cancer. All the radiation-sensitive cancers (thyroid, breast, leukemia, basal cell skin cancer) were increased. jamanetwork.com/journals/jam...

Cancer Incidence and Childhood Residence Near a Radioactive Waste Site

This cohort study examines the association between living near Coldwater Creek, Missouri, as a child and self-report of cancer incidence collected via surveys administered in the St Louis Baby Tooth–L...

jamanetwork.com

CT or "CAT" scans come with some cost. Of the 93 million CT examinations performed in 62 million US patients in 2023 were projected to result in approximately 103,000 future cancers. CT-associated cancers could soon account for 5% of all new cancer diagnoses annually. jamanetwork.com/journals/jam...

Projected Lifetime Cancer Risks From Current Computed Tomography Imaging

This risk model projects how many future cancers in the United States could result from annual computed tomography examinations.

jamanetwork.com

Randomized controlled trial comparing semaglutide (aka Ozempic & Wegovy) to tirzepatide (aka Zepbound & Mounjaro). Tirzepatide won hands down with 20.2% weight loss and waist down 18.4 cm. vs semaglutide with 13.7% weight loss and waist down 13.0 cm. www.nejm.org/doi/full/10....

Tirzepatide as Compared with Semaglutide for the Treatment of Obesity | NEJM

Tirzepatide and semaglutide are highly effective medications for obesity management. The efficacy and safety of tirzepatide as compared with semaglutide in adults with obesity but without type 2 di...

nejm.org

A breathtaking advance in the cancer fight. Instead of removing your T-cells and modifying them to recognize your cancer and re-infusing them - these investigators made a lipid bubble that carries mRNA to your T-cells instructing them to make the anti-cancer targeting antibody or CAR.

Science Magazine - Engineering immunotherapy from within

Harnessing a patient’s own immune cells to combat diseases while leaving healthy cells unharmed, called adoptive immunotherapy, is considered a powerful treatment option.

sciencemagazinedigital.org

The Felon's tariffs are driving up US healthcare insurance premiums by 2.2%-3.6% because insurers have to pay for more expensive imported drugs and devices. UnitedHealthcare is notifying state regulators of the premium hikes. www.kff.org/quick-take/t...

Tariffs Are Driving 2026 Health Insurance Premiums Up

President Trump has vowed to impose tariffs on a wide variety of goods from multiple countries. While consumers may expect the price of some imported goods to go up, what may be surprising is that the...

kff.org

Shingles is reactivation of the chickenpox virus (Herpes Varicella Zoster (HVZ) virus) in a nerve fiber as your immune defense weakens with time against it (largely because we don't get continued exposure to kids with chickenpox). It awakens in a nerve with blisters and severe pain called shingles.

If you want dementia, then don't get the shingles vaccine. 20% fewer seniors got dementia if they got the shingle vaccine in the UK! Now also shown in the USA. The more potent Shingrix is the shingles (HVZ) vaccine to get starting at age 50 - 2 doses 2 months apart! www.nature.com/articles/s41...

A natural experiment on the effect of herpes zoster vaccination on dementia - Nature

Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...

nature.com

Efficacy & safety data just keeps getting better for vaccines. FDA 1st approved the RSV vaccine in 2023-2024 and 1 year later it was 75% effective against infection, ER visits & hospitalizations in 60+ year olds. The Felon should resign for appointing Brainworm Bobby. jamanetwork.com/journals/jam...

Respiratory Syncytial Virus Vaccine for US Adults Aged 60 Years or Older

This case-control study assesses the safety and effectiveness of vaccines against respiratory syncytial virus (RSV) and the major adverse events among patients aged 60 years or older during the 2023-2...

jamanetwork.com

Young adults ages 40-49 are getting colon cancer at increasing rates. (I suspect microplastics.) This study just showed that testing your stool for iron reduced colon cancer deaths. I'd start screening at age 40 especially if you have a family history of colon cancer. jamanetwork.com/journals/jam...

Long-Term Effectiveness Associated With Fecal Immunochemical Testing for Early-Age Screening

This cohort study evaluates whether initiating fecal immunochemical test screening at age 40 to 49 years, rather than at the currently recommended age of 50 years, reduces colorectal cancer incidence ...

jamanetwork.com

Wow, the Ukrainians just destroyed or heavily damaged 40-plus high value Russian aircraft at four different airbases—this is 1/3 of their bombers. This is a crushing blow to Russian strategic airpower and is Ukraine's most successful operation yet. phillipspobrien.substack.com/p/weekend-up...

Weekend Update#135 (Update): The Ukrainians Just Pulled Off The Most Successful Operation Of The War

Phillips’s Newsletter is a reader-supported publication.

phillipspobrien.substack.com

Ignoring Brainworm Bobby what do the medical societies say re: COVID vax in pregnancy? The American College of ObGyns recommends COVID vaccination in pregnancy because pregnancy raises risk of severe COVID. Vax reduces risk of death & adverse perinatal outcomes. pubmed.ncbi.nlm.nih.gov/36649624/

Coronavirus Disease 2019 (COVID-19) Vaccination in Pregnancy - PubMed

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnancy is associated with significant maternal morbidity and mortality, and its risks can be mitigated with coronavirus dis...

pubmed.ncbi.nlm.nih.gov

When people lose Medicaid, they die. We now have a huge New England Journal of Medicine study of almost 1 million dual Medicare-Medicaid (so old and poor both) who lost Medicaid from 2015-2023. They die because they couldn't afford their medicines. www.nejm.org/doi/full/10....

Loss of Subsidized Drug Coverage and Mortality among Medicare Beneficiaries | NEJM

A total of 14 million Medicare beneficiaries receive the Low-Income Subsidy (LIS), which reduces cost sharing in Medicare Part D. Losing the LIS may impede medication access and affect mortality. U...

nejm.org

(Bloomberg) Xi Jinping’s decision to stand his ground against Donald Trump could hardly have gone any better for the Chinese leader. "This is arguably the best outcome that China could have hoped for- the US backed down,” said Trey McArver, co-founder Trivium China. finance.yahoo.com/news/xi-defi...

Xi Defiance Pays Off as Trump Meets Most China Trade Demands

(Bloomberg) -- Xi Jinping’s decision to stand his ground against Donald Trump could hardly have gone any better for the Chinese leader. Most Read from BloombergA New Central Park Amenity, Tailored to ...

finance.yahoo.com

Persistent poverty, or living where ≥20% of people live below the poverty level over 30 years, was associated with a 26% higher cancer risk in children. Poor children were 15% more likely to die from their cancer, including leukemia & solid tumor cancers both. publications.aap.org/pediatrics/a...

Persistent Poverty and Pediatric Cancer Survival

10.1542/6369590702112Video AbstractPEDS-VA_2024-0699736369590702112BACKGROUND. Cancer is the leading cause of death by disease among US children. While previous studies have examined the impact of pov...

publications.aap.org