Excited to share our new study showing how rhabdomyosarcoma cells respond differently to the inhibition of cholesterol synthesis compared to healthy myoblasts. Great work by a recent PhD Nebeyu Gizaw🎓 #UniHelsinki @wrihelsinki.bsky.social #UniJyvaskyla

EMBO Molecular Medicine@embomolmed.org · 9mo ago

Online today! Inhibiting #cholesterol synthesis halts #rhabdomyosarcoma growth via #ERstress and cell cycle arrest By N.Y. Gisaw, @riikka-k.bsky.social & colleagues @helsinki.fi @wrihelsinki.bsky.social 🗞️ doi.org/10.1038/s443...

Our new study together with @juhahulmi.bsky.social shows that: Mechanical loading induces distinct and shared responses in endothelial and muscle cells and reveals exercise-like molecular profiles @wrihelsinki.bsky.social www.biorxiv.org/content/10.1...

Mechanical loading induces distinct and shared responses in endothelial and muscle cells and reveals exercise-like molecular profiles

Skeletal muscles and blood vessels are continuously exposed to mechanical forces, particularly during exercise. We subjected human endothelial and skeletal muscle cells to cyclic mechanical stretch an...

biorxiv.org

Our latest article demonstrating how human skeletal muscle use glucose for muscle growth👇

Sakari Mäntyselkä@smantyselka.bsky.social · 10mo ago

I am pleased to share our new research article (in press version) entitled Glycolytic metabolism and biomass production from glucose in human skeletal muscle growth. Link in the comments. 1/3 #myoblue #SkeletalMuscle

Check our recent paper on the role of vasculature in skeletal muscle growth @apsphysiology.bsky.social @wrihelsinki.bsky.social

Juha Hulmi@juhahulmi.bsky.social · last yr.

Our study led by @riikka-k.bsky.social demonstrate benefits of the combined gene delivery of Pro-MSTN and VEGF-B on muscle growth & body comp. The scRNAseq results suggest various cell types & their crosstalk in muscle growth. tinyurl.com/4tnnrh7a @apsphysiology.bsky.social ‪

www.biorxiv.org/content/10.1... Check how differently muscle cells and endothelial cells respond to mechanical loading from our latest study. Great work by @erikniemi.bsky.social @smantyselka.bsky.social and collaboration with @juhahulmi.bsky.social. Supported by @wrihelsinki.bsky.social

Mechanical loading reveals cell type-specific responses and role of PHGDH in endothelial cell growth

Skeletal muscle and blood vessels are constantly subjected to mechanical forces, especially during exercise. We subjected human endothelial cells (ECs) and muscle cells (MCs) to cyclic mechanical stre...

biorxiv.org

Exciting days ahead at the Wihuri Research Institute @wrihelsinki.bsky.social as we host #WRISymposium and #EVBOSummerSchool next week in Helsinki. Looking forward to inspiring talks and scientific exchange with the #VascularBiology community! wri.fi/research-act... evbo.org/index.php/ev...

Wihuri Research Institute Symposium 2025 - Wihuri Research Institute

Since 2013, the Wihuri Research Institute (WRI) has been organizing the annual WRI Symposium, providing a platform for researchers and students to share knowledge and insights in cardiovascular resear...

wri.fi