Robert Lufkin MD

@robertlufkinmd.bsky.social

Professor & NYT bestselling author of Lies I Taught in Medical School. Metabolic health, longevity & what your doctor gets wrong. Free weekly newsletter → robertlufkinmd.substack.com

A shingles shot cut major cardiac events 46%. Not a statin. Not a stent. A vaccine. New data from the American College of Cardiology's Annual Scientific Session (ACC.26) analyzed 246,822 U.S. adults over 50 with atherosclerotic heart disease. Half had received Shingrix or Zostavax. (1/6)

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Our new longevity movie just premiered on Apple TV. It's called Forever Young. I had the privilege of joining a remarkable group of scientists, physicians, and patients to explore one of the most profound questions in medicine: can we slow, stop, or even reverse aging? (1/4)

I've spent decades trying to understand why some patients age gracefully into their 90s and 100s while others accumulate disease in their 60s. A new study in GeroScience gives us a chemical fingerprint. (1/6)

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New in JAMA Network Open: a machine-learning model that reads your EEG while you sleep can estimate your "brain age" -- and every 10 years your brain looks older than you are, dementia risk jumps by nearly 40%. (1/6)

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A 3-year gap in physiological age between adults with high vs. low cultural engagement — museums, cinema, theater. That is the headline finding of a longitudinal analysis in the Journal of Epidemiology and Community Health. (1/6)

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New this week in The Lancet Oncology: a phase 3 trial of cretostimogene grenadenorepvec — an oncolytic immunotherapy dripped into the bladder — in 112 patients with high-risk, BCG-unresponsive non-muscle-invasive bladder cancer, the population that usually faces removal of the entire (1/9)

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New in Diabetes Care: the ORDER you eat your food may control your blood sugar almost as much as WHAT you eat. In a randomized crossover trial (Diabetes Care, 2025), 20 adults with type 2 diabetes wore continuous glucose monitors and ate the same meals in two sequences — carbs first vs. (1/7)

When you sleep may matter more than how long. 😴 "Get your eight hours" may be the wrong target. When scientists tracked how people actually slept, the TIMING of sleep predicted survival better than the number of hours. (1/8)

28% Lower Dementia Risk From Two Foods You Probably Already Have That's the finding from a UK Biobank analysis of 121,986 adults. The highest consumers of flavonoid-rich foods — particularly tea and berries — had a 28% lower risk of dementia than the lowest consumers. (1/7)

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"Skinny Fat" Isn't Vanity. It's an 83% Higher Risk of Dying. Conventional wisdom: if your BMI is normal, you're fine. That's wrong. New data from the English Longitudinal Study of Ageing: 12 years of follow-up, 5,440 adults age 50+, published in Aging Clinical and Experimental Research. (1/7)

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New in JAMA Network Open: Harvard researchers tracked 92,383 American adults for 28 years, checking their diets every four years, and asked a simple question — does everyday olive oil have anything to do with how people die? (1/7)