An axonal sodium current gates motoneuron doublets and force amplification https://www.biorxiv.org/content/10.64898/2026.07.29.741588v1
New preprint! We identify the mechanism behind motoneuron doublets, closely spaced spike pairs that amplify muscle force, and show that initial and repetitive doublets share one axonal mechanism, gated by neuromodulation. www.biorxiv.org/content/10.6... (1/12)
An axonal sodium current gates motoneuron doublets and force amplification
Brief high-frequency bursts of action potentials shape neural coding. In spinal motoneurons, they appear as doublets, closely spaced spike pairs observed for a century that amplify muscle force nonlin...
biorxiv.org
Rapid experience-dependent tuning of spinal and transcortical stretch reflexes supports goal-directed movement https://www.biorxiv.org/content/10.64898/2026.04.29.721632v1
Curious to understand the identifiability of motor neuron spike trains from muscle activity using multichannel surface EMG or ultrasound? Here, we revisited the convolutive BSS model providing new theoretical insights verified with in silico experiments. doi.org/10.48550/arX...
Revisiting convolutive blind source separation for identifying spiking motor neuron activity: From theory to practice
Objective: Identifying the activity of motor neurons (MNs) non-invasively is possible by decomposing signals from muscles, e.g., surface electromyography (EMG) or ultrasound. The theoretical backgroun...
doi.org
Abstract submission is live for the 2025 Motoneuron meeting in St. John’s, Newfoundland. Deadline for submissions is 0830 NST on March 11, 2025. If you’re interested in Motoneurons - please join us! Visit Motoneuron.org to submit!
