Rosetta Commons

@rosettacommons.bsky.social

Rosetta Commons is the central hub for hundreds of developers and scientists from ~100 universities and laboratories to contribute and share the Rosetta source code. Rosetta Commons members develop software improvements to solve their unique queries.

A satellite event to European RosettaCon, the European Rosetta Workshop will take place on October 22-27 in Oeiras, Portugal. Participants, from all career stages, will get hands-on experience with the latest computational protein design methods using Rosetta and AI-based tools. zurl.co/AB2Ry

An event announcement about the European Rosetta Workshop 2026. The image shows a sunset on a beach in Oeiras, Portugal. The text reads “European Rosetta Workshop, Methods of computational protein design, October 22-27, 2026, ITQB Nova - Lisbon, Portugal, Registration Closes August 15, Learn more at rosettacommons.org/events.” The background is a light teal with some hexagons on it. The Rosetta Commons logo is in the upper right corner.

Meet Qian! Qian’s lab is leveraging large-scale datasets, AI methods, and evolutionary principles to uncover protein functions, understand their roles in disease, and develop computational strategies for therapeutic discovery. Learn more about Qian in our July 2026 newsletter. zurl.co/gnlC6

A picture of Qian Cong along with the text “Member Spotlight, Qian Cong, Assistant Professor, UT Southwestern Medical Center.” It also includes a quote that states “IBy combining AI with expertise in large-scale genomic and protein data analysis, my lab seeks to uncover how proteins interact, function, and evolve.” The background is a light orange. The Rosetta Commons logo is at the top and spiral teal and orange proteins are at the top and bottom of the image.

One week until Summer RosettaCon 2026! Virtual registration is open through August 6. Don’t miss our exciting lineup of speakers, including our invited speakers: Cameron Glasscock, Gye Rie Lee, Terra Sztain, and Martin Pacesa. Visit rosettacon.org to see the full scientific program and register.

An announcement of the invited speakers for Summer RosettaCon 2026. It shows a picture of the four invited speakers with their name and affiliation listed below. It notes that the conference is August 3-7, 2026 and that virtual registration is open at rosettacon.org. It has the Rosetta Commons logo in the upper left corner. There is solid teal at the bottom with connected hexagon designs in the corners.

The IPD Women in Science would like to invite you to attend a social hour ahead of Summer RosettaCon at the Institute for Protein Design on UW's campus! This event is open to all conference attendees and locals and takes place on Aug 3 at 2:30 p.m. Please RSVP by Wed, July 29: zurl.co/ahfJJ

An announcement about a pre-conference social hour. It says the eventi s hosted by IPD Women in Science, with the IPD logo, and that it will take place on August 3, 2026 at 2:30 p.m. It asks for an RSVP by July 29. It has a photo on top of three people talking in a hallway and has a white bottom part of the image with pink and purple hexagons on either side of the text.

In Spring 2026, the FEBS Advanced Practical Course on Generative AI for Protein Engineering was hosted in Belgium, where students participated in training on protein design pipelines. Then, CNPEM in Brazil hosted its annual Open Science Event introducing people to protein design through Foldit.

Pictures from two events. The “April 2026 FEBS Advanced Practical Course” image is on top and is a group picture of attendees in front of a building. The bottom image for the “May 2026 CNPEM Open Science Event” shows a child interacting with a protein on the screen. The text on the bottom says “Learn more at rosettacommons.org/news.” The Rosetta Commons logo is on the bottom left. The background is black with images of spiral proteins on the top and bottom.

Meet Rosemary, Colter, Noah, James, and Callia. Combining computational and biological research in protein design, these talented undergraduates will be joining the Damo Lab, Gray Lab, IPD, Drew Lab, and Schoeder Lab to help solve challenges that impact health and environmental sciences. #REU26

Meet REU trainees Kelvin, Allie, Keagan, Hannah, Sina, and Alan. With specialized research projects in protein design, these skilled undergraduates will be joining the Ovchinnikov Lab, Whitehead Lab, Samanta Lab, Yarov-Yarovoy Lab, Tandem AI, and IPD. #REU26

The scientific community is currently debating how to balance open research with biosecurity protections when it comes to biological AI tools. Primarily designed for broader societal benefits, could these tools also provide opportunities for misuse? Where do you stand? zurl.co/ccYXT

An announcement about an article focused on biosecurity. The image shows three graphics, a computer code looking circle with a rainbow protein spiral in the center and an open lock on the right, a protein spiral question mark, and a warning triangle with an exclamation point in the center. The background of the image is a gradient of green, yellow, and red from left to right. The text reads “Debating model openness versus biosecurity guardrails, The rapid advancement of biological AI tools has sparked a critical debate regarding the balance between open source research and biosecurity, A recent Nature article explores where scientists currently stand, Learn more at rosettacommons.org/news.” The background is a light teal with some hexagons on it. The Rosetta Commons logo is in the upper right corner.

Biohub has released updates to open source ESM protein language models. The models were used to generate the ESM Atlas, which maps 6.8 billion sequences and 1.1 billion predicted structures to protein functions. Alex Rives (Head of Science) is a keynote speaker for Summer RosettaCon. zurl.co/6qQdT

A news announcement about the release of Biohub’s open source models. The image shows a green and blue protein binding together graphically represented. The text reads “Biohub announces release of open source models, Biohub has released open source ESM protein language models that use evolutionary data to streamline drug discovery and map functional protein spaces, Learn more at rosettacommons.org/news.” The background is a light teal with some hexagons on it. The Rosetta Commons logo is in the upper right corner.

Meet Thomas! Thomas’ lab focuses on developing computational tools for determining 3D structures, including research into genetic code expansion and paramagnetic NMR to understand protein-protein interaction and molecular dynamics. Learn more about Thomas in our June 2026 newsletter. zurl.co/2QTmm

A picture of Thomas Huber along with the text “Member Spotlight, Thomas Huber, Full Professor, Australian National University.” It also includes a quote that states “I think the openness, friendliness, and helpfulness of the community are what I value the most.” The background is a light orange. The Rosetta Commons logo is at the top and spiral teal and orange proteins are at the top and bottom of the image.

Meet Iris, Daniel, Marwa, Tony, Olivia, and Andy. Working on new research projects in protein design, these accomplished undergraduates will be joining Merck Cambridge, the Khmelinskaia Lab, Merck South San Francisco, the Hosseinzadeh Lab, the Oberdorfer Lab, and the Cooper Lab. #REU26

OpenBind is generating high-quality protein-ligand datasets that link structural data with binding measurements. This first release provides a realistic, structurally novel testbed linking high-resolution crystallographic data directly with biophysical binding affinity. zurl.co/PVCnJ

A news announcement about the release of OpenBind’s first open source dataset. The image shows a multi-colored protein spiral graphically represented. The text reads “OpenBind announces release of first open source dataset, OpenBind released its first public dataset linking protein-ligand structures with experimental binding affinities to improve structure-based machine learning models, Learn more at rosettacommons.org/news.” The background is a light teal with some hexagons on it. The Rosetta Commons logo is in the upper right corner.

Meet Steven, Celeste, Peter, Martina, and Francisco. Eager to spend their summer diving deep into the world of protein design, these talented undergraduates will be joining the IPD, Ljubetič Lab, Strauch Lab, and Khare Lab to improve their skills and gain valuable experience in the field. #REU26

Abstracts for the first RosettaCon Asia, hosted by Peking University, are due June 15 with registration closing July 15. Join leading scientists in Beijing, China on October 10 - 11 to dive into discussions about the transformative era of protein design. To learn more, visit zurl.co/DkaQK

n announcement of RosettaCon Asia on October 10 - 11, 2026 at Peking University in Beijing, China. It has an orange background with protein spirals next to the top text. In the middle is a sunset colored image of a lake view of a building at Peking University. At the bottom it states that the conference is sponsored by Rosetta Commons with the white version of the logo, abstracts due June 15, registration closes July 15, and shares the URL rosettacommons.org/events/rcasia.

Registration for the 2nd Symposium on Protein Design and Engineering (RosettaCon Brazil), hosted by CNPEM, closes on June 15. Join the discussion on AI for protein design in Campinas, Brazil on October 5-8. A travel grant for a postdoctoral researcher is also available, learn more: zurl.co/dsjlS

There is a blue and tan image of a protein molecule along with the announcement of the 2nd symposium on protein design and engineering: AI for protein design. It states that the symposium will take place October 5 - 8, 2026 at CNPEM in Brazil. At the bottom against a teal background it states that the symposium is sponsored by Rosetta Commons with the logo in white, registration closes June 15 and has the URL rosettacommons.org/events/rcbrazil.

Welcome to our 2026 REU trainees! They spent the week at John Hopkins University completing an introductory bootcamp focused on machine learning and Rosetta software and tools. We can’t wait to see what they accomplish over the summer at their host labs throughout the US and Europe. zurl.co/LhlOI

Group photo of REU trainees on a brick pathway next to trees.Group photo of REU trainees jumping while standing in a line on a brick pathway next to trees.

Applications close this Friday, June 5, for the ML & Rosetta Intro Bootcamp. This immersive, novice-level bootcamp is designed for students and researchers who are new to computational protein design as a way to learn both machine learning tools and Rosetta. Apply today: zurl.co/ISb1i

An event announcement about the ML & Rosetta Intro Bootcamp applications closing soon. The image shows a computer screen with code on it with a person’s hands typing. The text reads “ML & Rosetta Intro Bootcamp, July 20 - 24, 2026, John Hopkins University - Baltimore, MD, Application Deadline is June 5, Learn more at rosettacommons.org/events.” The background is a light orange with some hexagons on it. The Rosetta Commons logo is in the upper right corner.

Registration is now open for the Leipzig Rosetta Workshop on August 17 - 21 in Leipzig, Germany. The hands-on workshop is focused on the latest computational protein design methods using Rosetta and AI-based tools such as RFdiffusion and ProteinMPNN. Applications close July 1, 2026: zurl.co/UTyIs

An event announcement about the Leipzig Rosetta Workshop 2026 now having registration open. The image shows a green grassy area in front of a sunset lit sky and a city view of Leipzig. The text reads “Leipzig Rosetta Workshop 2026 Registration Open, The workshop is focused on the latest computational protein design methods and AI-based tools, August 17 - 21, 2026, Leipzig University - Leipzig , Germany, Learn more at rosettacommons.org/events.” The background is a light teal with some hexagons on it. The Rosetta Commons logo is in the upper right corner.

Meet Anum! Anum’s lab looks at how proteins change conformations at different timescales to perform functions, how this behavior evolves, and how to capitalize on this knowledge to engineer new proteins with very sophisticated functions. Learn more in our May 2026 newsletter. zurl.co/OzCxg

A picture of Anum Glasgow along with the text “Member Spotlight, Anum Glasgow, Assistant Professor, Columbia University.” It also includes a quote that states “I’ve been wondering how millions of protein functions could arise from just a few thousand protein folds found in nature.” The background is a light orange. The Rosetta Commons logo is at the top and spiral teal and orange proteins are at the top and bottom of the image.

Join us July 20-24, 2026 for the ML & Rosetta Intro Bootcamp at John Hopkins University. The bootcamp will be a blend of lectures and hands-on projects to introduce and then practice key concepts and skills with Rosetta and machine learning. Applications close June 5. Apply now: zurl.co/N6eSW

An event announcement about the ML & Rosetta Intro Bootcamp now having applications open. The image shows two people working in front of computer screens with code on them. The text reads “ML & Rosetta Intro Bootcamp Applications Open, An intro to protein design with Rosetta and ML with a blend of lectures and hands-on projects, July 20 - 24, 2026, John Hopkins University - Baltimore, MD, Learn more at rosettacommons.org/events.” The background is a light teal with some hexagons on it. The Rosetta Commons logo is in the upper right corner.