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Rottinger Lab

@rottingerlab.bsky.social

Stress response | Regeneration | Longevity Our work at the Institute for Research on Cancer & Aging in Nice (IRCAN) is inspired by fascinating biological and physiological features of cnidarians.

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Rottinger Lab@rottingerlab.bsky.social · 8mo ago

Stoked that this paper, summarizing a vast series of experiments from past and present members of the team is out. A great way to end this year. www.nature.com/articles/s41...

Whole body regeneration deploys a rewired embryonic gene regulatory network logic - Nature Communications

To what extent regeneration recapitulates embryonic development is a longstanding question. Here, they show that embryonic gene modules are re-used, rewired, and interconnected to specific injury-indu...

nature.com

Rottinger Lab@rottingerlab.bsky.social · 2y ago

The second paper from the team, by @joao-e-carvalho.bsky.social, that was accepted by the end of last year @biologists.bsky.social is now online. In collab with @planktovie, we show how to close the #Nematostella lifecycle in 2mo and optimize gene editing journals.biologists.com/dev/article-...

Optimized husbandry and targeted gene-editing for the cnidarian Nematostella vectensis

Summary: Optimized life cycle, in combination with efficient gene-editing approaches, facilitates the establishment of genetic tools in N. vectensis, an emerging model for environmental stress respons...

journals.biologists.com

Rottinger Lab@rottingerlab.bsky.social · 2y ago

Great to ses that study out in MBE. This is the result of an effective collaboration with @stemdevevo.bsky.social. Aurore Vullien (joint PhD student) et al has studied the evolution and role of ROS in metazoan regeneration using #nematostella and #platynereis. Congrats to all. Highlights below.

Stem Cells, Regeneration & Evolution@stemdevevo.bsky.social · 2y ago

Brand new ms coming out at #MolBiolEvol of the collaboration between @stemdevevo.bsky.social and @rottingerlab.bsky.social Aurore Vullien joint PhD student investigated the role of ROS in metazoan regeneration, focusing on Platynereis and Nematostella academic.oup.com/mbe/article/...