🐜 Fungus-growing ant species make a host defence peptide (abaecin-2) with a copper-binding effect that is either inhibitory or protective! ➡️ Read more about these dual roles of this HDP in the newest publication out now in #RSCChemBio 👉 http://doi.org/10.10... #HDP

We’re excited to announce the 22nd International Conference on Biological Inorganic Chemistry (ICBIC22). Join award-winning speakers for plenary, keynote, invited & contributed talks, submit to our poster session & join a full social programme with your community: https://www.icbic2027.org #ChemSky

📢 Don't miss this Communication from Shuo Han and his team introducing NovaID: a HyperNova-based compact and versatile proximity labeling platform! ➡️ Read more here: doi.org/10.1039/d6cb... 👏 Shuo Han is one of our 2026 Emerging Investigators... Stay tuned to hear more!

RSC Chemical Biology is delighted to be partnering with the #SBNP conference. The final deadline is closing on Tuesday 11th August 2026. If your considering joining the conference register now. Click here for more information: https://bit.ly/4bHu5Q7

📢 Don't miss your chance to register for the 10th RSC BMCS Fragment-based Drug Discovery Meeting happening from 14-16th September in Cambridge at Churchill College, University of Cambridge! #Fragments2026 ➡️ Find out more and register here! www.rscbmcs.org/even... www.eventsforce.net/...

There is less than one month left to submit your poster abstract for this year's Chemical Science symposium! Abstract submission closes on 20th August - we hope to see you in October for two days of talks and discussions on digital chemistry! Further information here: rsc.li/chemscisymp2026

🔥 Don't miss this HOT review from #RSCChemBio on mechanism-based HDAC inhibitors! ➡️ Read the article by David Christianson here! doi.org/10.1039/d6cb... #EnzymeInhibition

Catch up on the latest news from RSC Chemical Biology in the journal newsletter, available on our blog at the link below. Signing up to receive new issues by email at rsc.li/alerts blogs.rsc.org/cb/july-2026...

We're pleased to share that Professor Boris Vauzeilles has joined our Editorial Board as an Associate Editor. Prof. Vauzeilles is a CNRS Research Director and Director of the Institut de Chimie des Substances Naturelles (ICSN, CNRS, France). Find out more on our web page: www.rsc.org/people/boris...

✨ "The VanVeller lab is exploring amidine peptide-backbone modifications. By replacing the native amide with an amidine they directly alter a key site of protease recognition while preserving side-chains necessary for activity at opioid receptor GPCRs." ➡️ doi.org/10.1039/d6cb...

📢Issue 7 of RSC Chemical Biology is now online and #OpenAccess ✨ Find articles on peptidomimetic GABRAP ligands, artificial nicotinamide cofactors, chlorophyll biosynthetic enzymes and much more! ➡️ Read it here: pubs.rsc.org/cb/issu...

📢 Don't miss Toru Komatsu and Yasuteru Urano's newest review in #RSCChemBio where they 'revisit the past to discover the new.' ✨ Their review explores how a century of classical chemistry continues to inspire modern enzyme-responsive fluorescent probes. Read it here: doi.org/10.1039/d6cb...

➡️ Have you seen this #RSCChemBio Advance Article out now from our newest themed collection on Biocatalysis? 🍄‍🟫Read Gideon Grogan, Will Unsworth and their team's report on the newest family I unspecific peroxygenase from Daldinia childiae: DchUPO! ✨ http://doi.org/10.10...

📢 Have you read this review from Frank Gunn-Moore FRSB FRSE and his team at the University of St Andrews? ✨ Find their evaluation of 17β-HSD10 inhibition towards developing therapies for Alzheimer's disease out now in #RSCChemBio! ➡️ Read it here: http://doi.org/10.10...

We're pleased to announce that PhD candidate Vanessa Rogga of the Tate laboratory at Imperial College London is the winner of our best poster award at this year's Gordon Research Conferences meeting on Induced Proximity! Please join us in congratulating Vanessa. www.grc.org/induced-prox...

🌿 From Christopher Neil Hunter The University of Sheffield, find the newest #RSCChemBio Perspective on chlorophyll! ➡️ Read their extensive review looking at everything Chl biosynthesis including new structural insights using AlphaFold! ✨ http://doi.org/10.10...

The structural chemistry and biosynthesis of chlorophylls

Chlorophylls (Chls) harvest the solar energy that drives photosynthesis, which underpins most of the food chains on our planet. Starting from protoporphyrin IX, just seven biosynthetic reactions culminate in the synthesis of Chl a, the major light-absorbing pigment on Earth. Other such pigments, Chls b, c, d and f,

doi.org

☀️ Happy Friday! ☀️ ➡️ Have you read George Lisi and his team's work on how the GM-CSF histidine triad toggles its structure for physiological and pathological interactions yet? ✨ Find it out now in #RSCChemBio 👉 http://doi.org/10.10...

Exploring the GM-CSF histidine triad as a modulator of structure, molecular motion, and ligand binding

Granulocyte macrophage-colony stimulating factor (GM-CSF) is a cytokine that plays a role in immune modulation. Its expression is associated with a multitude of effects ranging from harmful, as in diseases such as rheumatoid arthritis and multiple sclerosis, to beneficial, as in the mitigation of type-1 diabetes an

doi.org

📢 Call for Abstracts is OPEN! 📢 Join the GEM-APPICOM Joint Meeting in Lyon (Nov 3–6, 2026) for "At the Confluence of Biomembrane Sciences." 🧬🔬 From membrane proteins to computational biophysics—we want your research! ⏳ Deadline: July 1 🔗 gem-2026.sciencescon... #GEM2026 #Biophysics #Science

📢 Welcome to Issue 6 of #RSCChemBio! Read our cover articles using hybrid computational-experimental approach to probe acyl-carrier protein sequence diversity and RNA-amiloride binding respectively! doi.org/10.1039/D5CB... doi.org/10.1039/D6CB... ➡️Find the issue here! pubs.rsc.org/en/jour...

Meet one of our 2026 Emerging Investigators! Sascha Hoogendoorn is tipping the balance towards PLK4 degradation at centrioles with their newest manuscript in #RSCChemBio! Catch the manuscript here: http://doi.org/10.10... #PLK4

🏆 Congratulations to #RSCChemBio's Editor in Chief, Hiroaki Suga, who has been awarded the 2026 Antonio Feltrinelli International Prize in chemistry for his pioneering research in the fields of biology and biotechnology as applied to RNA and peptides!

Congratulations to Steven Bensinger, Keriann Backus and colleagues — winners of RSC Chemical Biology’s Outstanding Early Career Research Award for their work on STING-sterol interactions. 📖 Read the paper: doi.org/10.1039/D4CB... Read more about the winners on our blog: blogs.rsc.org/cb/oec...

📢 Stuart Conway and his team are working towards better understanding of the phosphatidylinositol 5-phosphate (PI(5)P) pathway with their novel photoaffinity probe. 👏 Read about how this new molecular tool here! doi.org/10.1039/D6CB... #RSCChemBio #PhotoaffinityProbes

Synthesis and characterization of a novel phosphatidylinositol 5-phosphate (PI(5)P) photoaffinity probe

Phosphatidylinositol 5-phosphate (PI(5)P) plays a crucial role in cellular signaling, cell proliferation, the DNA damage repair response, and gene transcription. However, the underlying mechanism of PI(5)P function in these cellular pathways is poorly understood. This lack of understanding results at least in part,

doi.org

🦠Anatoly Kolomeisky's latest #RSCChemBio review features chemical kinetics meets machine learning analysis meets antimicrobial peptide synergy! ✨ Read about their novel quantitative framework to explain antimicrobial peptide cooperativity here http://doi.org/10.10... #AMP

Cooperative membrane association as a mechanistic origin of synergistic antimicrobial peptide activity

Antimicrobial peptides (AMPs) are central components of the innate immunity system that can be found in almost all living organisms. They are promising alternatives to conventional antibiotics due to their broad-spectrum activity and reduced susceptibility to resistance. Experimental studies have shown that combina

doi.org

✨ How do you make peptides that are stable against proteolytic degradation? ➡️ Juan Del Valle and team are expanding the repertoire of peptide backbone modifications for chemically distinct and minimally perturbing strategies for stable peptides! 👉 Read it here! http://doi.org/10.10...

Backbone N-heteroatom substitution as a strategy to enhance peptide proteolytic stability

Peptide-based ligands are well-suited to engage large biomolecular surfaces but are often limited by rapid proteolytic degradation in biological environments. Backbone modification offers a direct means to disrupt protease recognition while preserving side chain functionality; however, many established approaches i

doi.org

🌿 Don't miss this #RSCChemBio article on a novel natural product, Igalan, which shows promise as an anti-inflammatory agent against sepsis! ✨ Read about how Igalan directly supresses NLRP3 inflammasome activation here: http://doi.org/10.10... #DrugDiscovery

Igalan attenuates sepsis-induced inflammation through covalent targeting of the NLRP3 inflammasome pathway

Macrophages play a critical role in sepsis, a life-threatening systemic inflammatory syndrome that necessitates urgent therapeutic intervention. Unfortunately, no approved drugs currently target this specific pathological mechanism. In this study, we identify Igalan, a natural compound that selectively disrupts mac

doi.org

📢 Have you read this #RSCChemicalBiology review from Carsten Schultz and Andrew Emili on the role of acyl-chain remodelling in protein-phospholipid interaction networks and cancer progression? ➡️ Catch it here! http://doi.org/10.10... #Phospholipids

Decoding protein-phospholipid interaction networks in cancer: the role of acyl-chain remodeling

Lipids, particularly phosphoinositides, are increasingly recognized as important markers and causal regulators in cancer progression. Less appreciated, however, are the functional consequences of changes in phospholipid acyl chain length and saturation. These alterations reshape membrane biophysics and rewire membr

doi.org

📢 Call for Abstracts is OPEN! Join the GEM-APPICOM Joint Meeting in Lyon (Nov 3–6, 2026) for "At the Confluence of Biomembrane Sciences." 🧬🔬 From membrane proteins to computational biophysics—we want your research! ⏳ Deadline: July 1 🔗 gem-2026.sciencescon... #GEM2026 #Biophysics #Science

Submissions to our upcoming themed collection on Epigenetics and epitranscriptomics are now open! Submissions can be made through to 30 September 2026. Find out more on our blog post: : blogs.rsc.org/cb/call-cbep...

Don't miss this year's GRC on Induced Proximity Modalities and Therapeutics - "Expanding Proximity Driven Pharmacology and Drug Discovery". Our Editorial Board member Michelle Arkin is vice-chairing, and the journal is proud to be sponsoring the event. Find out more: www.grc.org/induced-prox...