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Hervé (rv) Técher

@rvtecher.bsky.social

Hervé (rv) TÉCHER, Chair of Professor Junior @Univ_CotedAzur and team leader @ircaninstitute. Investigating Genomic Instability 🧬 and inflammation. 🇫🇷 🇷🇪 🇨🇳 🇮🇹. Opinions are my own. https://www.ircan.org/research/teams/herve-techer/

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Hervé (rv) Técher@rvtecher.bsky.social · 5mo ago

Happy to share the first research article of our team. We report that foreign DNA, such as ISD, activates DNA damage signaling mainly through DNA-PK. @ircan.bsky.social @univcotedazur.bsky.social @cnrsbiologie.bsky.social @canceropolesud.bsky.social www.jbc.org/article/S002...

Interferon Stimulatory DNA activates the DNA damage signaling through ATM and DNA-PK sensing

In eukaryotic cells, DNA is normally confined in the nucleus and mitochondria and the presence of DNA in the cytoplasm is a danger signal that activates innate immune responses. Upon detection of cyto...

jbc.org

Hervé (rv) Técher@rvtecher.bsky.social · 6mo ago

If you are interested in chromosomal instability, micronuclei and more, I suggest reading this book: link.springer.com/book/10.1007... We wrote chapter on transcription-replication conflicts and micronuclei with my mentor @paserolab.bsky.social @ircan.bsky.social @univcotedazur.bsky.social

Chromoanagenesis

This book explores chaotic genomic rearrangements, known as chromoanagenesis, their formation mechanisms, and the techniques used to detect them.

link.springer.com

Hervé (rv) Técher@rvtecher.bsky.social · 6mo ago

Follow our research and lab here: www.ircan.org/research/tea... If you are interested in joining the lab, we are looking for our future labmates and for future students, at all levels.

Genomic Instability in Human Pathology & Aging – IRCAN

Cette année encore de nombreux IRCANiens se sont mobilisés pour accueillir le public et animer des ateliers permettant d’illustrer les recherches sur le cancer et le vieillissement menées à l’IRCAN.

ircan.org