Really excited to share the publication of my PhD work in the Jin Zhang lab at UCSD! You can find it here in Nature Chemical Biology. www.nature.com/articles/s41...
A chemigenetic endogenous Ras activity biosensor for live-cell pharmacology - Nature Chemical Biology
Here the authors present a biosensor for measuring endogenous Ras in live cells, based on HaloTag and the fluorogenic JF635 dye, and they use it to report location-specific inhibition profiles of dist...
nature.com