New preprint! 🎉 We discovered an unexpected way that the postsynaptic scaffold protein Densin-180 binds SHANK proteins. Instead of using a conventional C-terminal PDZ-binding motif, Densin-180 uses an internal PDZ-binding motif that engages the canonical SHANK3 PDZ domain. 🧵1/8

Join scientists working on #ProteinHomeostasis in the EMBO Workshop "Proteostasis shaping health span: From protein folding to failure" in #Ericeira, #Portugal, 9–13 November 2026. Deadline: 1 September 2026 https://meetings.embo.org/event/26-proteostasis #EMBOproteostasis #EMBOevents 🧪

Join us at the @crick.ac.uk for the 2026 meeting of the UK proteostasis community! We especially encourage students and postdocs to attend and share their work. All talks (except the keynotes) will be selected from abstracts.

Proteostasis UK@proteostasisuk.bsky.social · 8mo ago

📣 UK Proteostasis Meeting 2026 – Registration Now Open! I’m delighted to share that registration is now open for the UK Proteostasis Meeting 2026, hosted by The Francis Crick Institute on 20–21 July 2026
. Please register here(lnkd.in/ervXMzWN) and through Eventbrite for payment (lnkd.in/eTxqjnQy)

Time to close the EMBO-FEBS Susan Lindquist School on Proteostasis 2025 in Espoo, Finland. Four intensive days of fabulous presentations, discussions, and mentoring, fostering scientific exchange between senior and junior members of the proteostasis field. Thank you to all participants!

Excited to share our new preprint in @biorxiv-neursci.bsky.social "Cyclin-dependent kinase-like 5 (CDKL5) binds to talin and is anchored at the postsynaptic density via direct interaction with PDZ domains" Instead of a 🧵 the paper is summarised in this video. www.biorxiv.org/content/10.1...

Call for Applications: Wiko Early Career Call for #fellowships 2026/27 in the #NaturalSciences and #LifeSciences. Apply online by November 1st for a 3–5 month fellowship at the Wissenschaftskolleg zu Berlin – Institute for Advanced Study: wiko-berlin.de/fellow-werde... #cfa

Last call to apply for the Susan Lindquist School on Proteostasis EMBO-FEBS Lecture Course, 16-19 Sept 2025 in Espoo, Finland! Open for postdocs and PhD students. DL June 15! meetings.embo.org/event/25-pro...

For those interested in yeast amino acid control, we've developed fluorescent reporters to simultaneously monitor amino acid synthesis and uptake activities (GAAC, TORC1, and SPS) in single cells: www.molbiolcell.org/doi/10.1091/...

We are looking for a postdoc with microbiology background for #superresolution #singlemolecule #ERC tracking project. Apply by 27.4.2025. 🦠🔬🧫 Pls share! www.aalto.fi/en/open-posi...

Apply now for the Susan Lindquist School on Proteostasis EMBO-FEBS Lecture Course, 16-19 Sept 2025 in Espoo, Finland! Top speakers cover the latest in proteostasis. Open to 60 PhDs & postdocs. Deadline: 15 June 2025. meetings.embo.org/event/25-pro...

Susan Lindquist School on Proteostasis

Cells constantly surveil and monitor their proteome to ensure proper function. These processes, spanning multiple steps from protein synthesis to folding and degradation, are collectively known as pr…

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