Chise

@sailorrooscout.bsky.social

Senior Scientist | Vaccine Research & Development | NIH | NIAID | VRC | 🧬🧫🦠🔬💉🥼🥽 | 🏳️‍🌈 | @coralchimera.bsky.social 💍 | @phoenixnest.bsky.social & @multicolorbark.com & @likeapalette.com 🧵🪡

GOOD NEWS! A new cancer treatment has demonstrated unprecedented results in a large trial for cancer patients whose disease has become resistant to chemotherapy AND immunotherapy. Tumors shrank in OVER a third of participants, with 15 patients experiencing COMPLETE eradication of their tumors.

GOOD NEWS! A new cancer treatment has demonstrated unprecedented results in a large trial for cancer patients whose disease has become resistant to chemotherapy AND immunotherapy. Tumors shrank in OVER a third of participants, with 15 patients experiencing COMPLETE eradication of their tumors.

WELL NOW, would you look at that? A massive, 24-YEAR-LONG study of MORE THAN 1.2 MILLION people in Denmark found NO LINK between aluminum in childhood vaccines and autism, asthma, OR chronic disorders. Aluminum is an ADJUVANT. It ENHANCES your immune response to a vaccine. That’s it.

GOOD NEWS! Phase I clinical trial results out of WashU Medicine show a first-of-its-kind personalized DNA vaccine designed to treat MGMT-unmethylated glioblastoma is safe AND elicits robust and broad immune responses that appears to INCREASE recurrence-free survival in patients after surgery.

Personalized DNA Vaccine Shows Immune Activation and Survival Signals in Glioblastoma Trial

Personalized neoantigen vaccine triggered immune responses and promising survival outcomes in MGMT-unmethylated glioblastoma Phase I trial patients.

insideprecisionmedicine.com

GOOD NEWS! Phase I clinical trial results out of John Hopkins show a first-of-its-kind vaccine designed to target common KRAS mutations was safe AND stimulated KRAS-specific T-cell responses in 90% of study participants who were at HIGH risk of developing pancreatic ductal adenocarcinoma (PDAC).

Pancreatic Cancer Vaccine Triggers Immune Response Before Tumors Develop

Phase I results show early promise for a vaccine designed to prevent pancreatic cancer in people at high risk of developing the disease.

insideprecisionmedicine.com

GOOD NEWS! Researchers have discovered a new antibiotic, known as manikomycin, that may be a bulwark in the fight against drug-resistant superbugs. By attacking the ribosome in a never-before-seen way, manikomycin can EVADE the existing mechanisms pathogens have developed to resist antibiotics.

GOOD NEWS! A personalized mRNA vaccine, known as mRNA-4157, has shown promise in keeping melanoma, a deadly skin cancer, from returning. FIVE years later, NEARLY 70% of people in the vaccine group are CANCER-FREE. The vaccine also cut a person’s risk of the cancer metastasizing by NEARLY 60%.

A personalized vaccine for melanoma cut the risk of cancer returning after five years

If the vaccine is effective in a late-stage trial, it would be “paradigm-shifting,” one expert said.

nbcnews.com

Vaccines save lives. This is the FIRST time that ZERO cervical-cancer deaths have been recorded for this age group, and it’s thanks to the introduction of a vaccine against the human papillomavirus (HPV). Yes, you read that correctly. ZERO.

Cervical cancer deaths for vaccinated young women fall to zero in England: study

The HPV vaccine for cervical cancer has reduced the risk of dying from the disease before the age of 30 in England to almost zero, the first study of its kind showed Thursday.

ctvnews.ca

Published in The New England Journal of Medicine. Peer-reviewed. Large sample size. Sound methodology. An antiviral pill has, for the FIRST time, been shown to PREVENT COVID-19 in individuals exposed to SARS-CoV-2. Ensitrelvir blocks the enzyme coronaviruses need to make new copies of themselves.

GOOD NEWS! Researchers at Stanford University have developed a UNIVERSAL vaccine known as GLA-3M-052-LS+OVA, that protects against a wide range of respiratory viruses, bacteria AND even allergens. The vaccine is delivered intranasally AND provides broad protection in the lungs for several MONTHS.

Goodbye to seasonal viruses as we know them: the first universal vaccine against respiratory infections and allergies is now closer than ever

Scientists are getting closer to a universal nasal vaccine that could protect against respiratory viruses, bacteria and even allergies

ecoticias.com

WELL NOW, would you look at that? A massive, 26-YEAR-LONG study of MORE THAN 2.4 MILLION people in Sweden found NO EVIDENCE to support a causal link between acetaminophen (the API in Tylenol) use during pregnancy and increased risk of autism, ADHD, OR intellectual disability in children.

GOOD NEWS! Researchers have developed an HIV vaccine candidate that achieves something never before observed in the field: inducing detectable neutralizing antibodies (nAbs) against HIV within just THREE weeks after a SINGLE immunization which was further INCREASED after an additional booster.

Guys. Heads up. Let’s talk about Hantavirus. There have been SEVERAL bad takes and BLATANT misinformation circulating regarding this outbreak so I figured it was a good idea to make a thread about it. Stay calm. Stay vigilant. Know your facts. Here’s ALL you need to know. 🧪🧵⬇️

GOOD NEWS! Researchers have developed a bioengineered chewing gum that dramatically reduces cancer-linked microbes in the mouth, including human papilloma virus (HPV) and harmful bacteria tied to head and neck cancers offering a promising new approach for cancer prevention and treatment.

This is the most detailed 3D rendering of a eukaryotic cell to date, obtained using X-ray, nuclear magnetic resonance (NMR), and cryo-electron microscopy datasets. 🔬🧪

3D rendering of a eukaryotic cell obtained using X-ray, nuclear magnetic resonance (NMR), and cryo-electron microscopy datasets.

“Pancreatic cancer mRNA vaccine shows lasting results in an early trial. Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later.” This is why we should fund science. 🧪

Pancreatic cancer mRNA vaccine shows lasting results in an early trial

Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later.

nbcnews.com

GOOD NEWS! Researchers have made a HUGE breakthrough towards a UNIVERSAL antiviral. By targeting sugar molecules found on the surface of many viruses that SHARE structural similarities, they identified FOUR compounds that successfully BLOCKED infections from SEVEN different viruses.