Some great talks today on the first full day of #ISEEC2026 #CancerEvolution, many of them from my Moffitt colleagues talking about cancer ecology and evolution during treatment

What a wonderful Cretan ISEEC Conference that was! Four days bouncing around ideas about evolution, ecology, cancer, translational tech, the future of AI, and much more. See you again in two years!

Excited to announce Eco-Onco Exchange — a virtual seminar series bridging mathematical ecology and oncology. Each session pairs two speakers from each field around a shared theme, followed by joint discussion. First three sessions coming soon! Register here docs.google.com/forms/d/e/1F...

🎉 The SMB #MathOnco Subgroup is launching its inaugural Early Career Awards! Grad student or postdoc presenting at #ECMTB2026 / #SMB2026 in Graz? Apply by April 30th! 🔗 smb.org/call-for-award-nominations/

🎉 Excited to share our cover article in Cancer Research! We identified distinct tumor‑immune ecologies in lung cancer that predict immunotherapy response—moving beyond single biomarkers to spatial interactions. #CancerResearch #Immunotherapy #TumorMicroenvironment #Biomarkers Paper: t.co/cLLk8JX4UH

Had a fantastic time presenting my research at MathOnco25. Looking forward to IMO workshop! @mathonco.bsky.social

Last speaker at #MathOnco25 is our own @mathonco.bsky.social Jeffrey West that provides a study of the #mathonco literature to produce this definition of MathOnco: the use of interpretable models to understand and improve cancer therapy

Great last didactic at #MathOnco25 by @andriy-marusyk.bsky.social describing the complex landscape of evolutionary and ecological mechanisms aiding cancers become treatment-resistant. Andriy and I both share the idea of maps as an example of what models can be

4th (and last) day of #MathOnco25. Excellent work @sandyanderson.bsky.social and @gliomath.bsky.social. Looking forward the next one, hopefully in 2026

Last keynote at #MathOnco25 by Sarah Bruningk talking about #AI in #Medicine. While generally optimistic about AI in medicine she is aware of the challenge that AI works best when there is a lot of data and that is almost never the case in clinical oncology

In her #MathOnco25 plenary, Sarah Brüningk motivates mechanistic learning in mathematical oncology, drawing on her recent review paper: www.frontiersin.org/journals/imm...

Bob Gatenby finishes his phenomenal #MathOnco25 talk with this stunning figure and conclusion: "Cycles within cycles may allow metastatic prostate cancer to be converted to a chronic disease". The results are from a new paper: onlinelibrary.wiley.com/doi/10.1002/...

Joel Brown at #MathOnco25 draws parallels between the evolution and ecology of cancer and of dogs, elephant shrews and (of course) squirrels. Cancer redefined as "a disease of uncontrolled proliferation by transformed cells subject to evolution by natural selection". aacrjournals.org/mcr/article/...

Now @kitcgallagher.bsky.social at #MathOnco25 presents his recent research on predicting treatment outcomes to identify which patients will benefit the most from adaptive therapy. Preprints and papers at scholar.google.com/citations?us...

Franco Pradelli presents one of the most beautiful slides so far at #MathOnco25, on the topic of exploiting the cost of addiction in anaplastic large cell lymphoma

Fantastic to have adaptive therapy pioneer Jingsong Zhang here at #MathOnco25 talking about a third-generation adaptive therapy trial for metastatic prostate cancer underway at the Moffitt Cancer Center, informed by Jill Gallagher's mathematical modelling. Preprint: www.medrxiv.org/content/10.1...

Thursday keynote at #MathOnco25 with @robjohnnoble.bsky.social showing a wealth of #MathOnco models of cancer evolution and evolutionary-enlightened therapies. Notice the bingo card: he showed enough different math models to fill up the card!

Really nice #MathOnco25 talk by Einar Bjarki Gunnarsson on optimal dosing of anti-cancer treatment under drug-induced plasticity, showing "that the optimal dosing strategy steers the tumor to a fixed equilibrium composition between sensitive and tolerant cells" www.nature.com/articles/s41...

Optimal dosing of anti-cancer treatment under drug-induced plasticity - npj Systems Biology and Applications

npj Systems Biology and Applications - Optimal dosing of anti-cancer treatment under drug-induced plasticity

nature.com

Now at #MathOnco25, co-organiser @gliomath.bsky.social presents recent work showing that the predictions of an AI method massively improved when coupled with a mechnaistic mathematical model www.nature.com/articles/s41...

Biologically informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post treatment glioblastoma - npj Digital Medicine

npj Digital Medicine - Biologically informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post treatment glioblastoma

nature.com

From Tampa to the gorgeous St. Pete for #MathOnco25. Science and views for the next few days! 😍

Great talk by collaborator Joon Hyun Song from @ceel-damaghilab.bsky.social working on a simple model of the storage effect to explain the role of temporal fluctuations in intra tumor heterogeneity #MathOnco25

At #MathOnco25, @rrockne.bsky.social explains why he so loves SINDy (sparse identification of nonlinear dynamics).

Great didactic at #MathOnco25 by @rrockne.bsky.social who starts his presentation with a very Freudian slip by thanking organizers @gliomath.bsky.social and #SINDy (meaning @sandyanderson.bsky.social)

First plenary talk at #MathOnco25 today is Harvard's Galit Lahav about the temporal dynamics of p53 and how it lends itself to #MathModeling

Galit Lahav - Wikipedia

en.wikipedia.org

Day 2 of #MathOnco25 in St Pete Beach, FL

Great didactic at #MathOnco25 by @dwodarz.bsky.social showing the importance of space...and turnover in #cancerevolution

Our own Tatiana Miti highlighting the importance of data to find out the initial configuration of an ABM describing early stages in metastasis, something which is hard to study with experimental models and clinical data #MathOnco25

A man after my own heart! @dwodarz.bsky.social on the importance of spatial structure in tumour evolution #MathOnco25

At #MathOnco25, @cancerevo.org talks about how to model the role of the tumor microenvironment in cancer initiation, progression, and treatment resistance. He finishes by advertising the Moffitt IMO PhD program www.moffitt.org/education/re...

Now at #MathOnco25, @ceel-damaghilab.bsky.social advocates "3D spheroids as a simplest model of tumor ecosystem". His beautiful data make a strong case.