ICYMI—the December 15 issue received the most votes in our cover contest! Congrats to the authors of "Mathematical Oncology: How Modeling Is Transforming Clinical Decision-Making." buff.ly/4CPPV39 #MathOnco

Latest work from #CancerEvo @moffittnews.bsky.social @mathonco.bsky.social member Matt Froid working with @rrockne.bsky.social and friends at @cityofhope.bsky.social using #MathOnco to study the #JanusEffect in #AML: www.nature.com/articles/s41...

Overcoming vascular niche–mediated TKI resistance in acute myeloid leukemia through miR-126 inhibition - npj Systems Biology and Applications

npj Systems Biology and Applications - Overcoming vascular niche–mediated TKI resistance in acute myeloid leukemia through miR-126 inhibition

nature.com

🎉 The SMB #MathOnco Subgroup is launching its inaugural Early Career Awards! Grad student or postdoc presenting at #ECMTB2026 / #SMB2026 in Graz? Apply by April 30th! 🔗 smb.org/call-for-award-nominations/

We have a new Math Oncology special issue in npj Systems Bio Apps. Looking forward to receiving your submissions! Jointly edited by Jeffrey West, Sara Hamis, Robert Noble, & myself nature.com/collections/...

Mechanistic and data-driven modeling in mathematical oncology

This Collection invites research on recent methods and applications in mathematical oncology that lead to mechanistic insight into cancer dynamics through ...

nature.com

Read the latest articles in the Cancer Research special series, Driving Cancer Discoveries with Computational Research, Data Science, and Machine Learning/AI: buff.ly/EjkhVK5

"I think the current publication system is a runaway train that is headed for disaster. Without adequate scrutiny, the overall quality of research seems to be degrading." go.nature.com/4b8r0Zq

I’m going to halve my publication output. You should consider slow science, too

If we don’t slow down, the research enterprise is going to crash, argues Adrian Barnett.

go.nature.com

Brain food on our brain drainage system to help keep you healthy, with @jonykipnis.bsky.social erictopol.substack.com/p/how-our-br...

Is the point of mathematical research to know *what* is true or to know *why* it's true? Emily Riehl lays out a strong argument - and what it has to do with AI - along great advice for the field in @science.org www.science.org/doi/10.1126/...

Mathematics is hard for mathematicians to understand too

At a recent conference on mathematics in the age of automated proofs, mathematician and Fields Medalist Akshay Venkatesh presented “How do we talk to our students about AI?'' He quoted an email he'd r...

science.org

@dfrankhouser.bsky.social

preLights@prelights.bsky.social · 9mo ago

A mathematical model translates aggregated single-cell RNA sequencing data into stages of disease. #SystemsBiology Charis Qi highlights a recent #preprint from David Frankhouse, @rrockne.bsky.social & team #preLight ⬇️ prelights.biologists.com/highlights/l...

Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

A real challenge for science. Some good suggestions here but no silver bullet answer

Nature@nature.com · 12mo ago

Journals and funders are trying to boost the speed and effectiveness of review processes that are under strain go.nature.com/4oACp8A

A simple design framework that will massively improve your slides and your public speaking clauswilke.substack.com/p/slides-tha...

Slide designs that present themselves: The assertion–evidence template

Your slides are not your talk.

clauswilke.substack.com

Quantum mechanics is one of the most successful theories in science — and makes much of modern life possible go.nature.com/4mjXRg3

Physicists disagree wildly on what quantum mechanics says about reality, Nature survey shows

Nature - First major attempt to chart researchers’ views finds interpretations in conflict.

go.nature.com

Abstract submission is now open for #MathOnco25! So please go ahead and submit asap to have a chance of getting one of our travel awards: mathematical-oncology.org/mathonco25

A packed opening plenary from one of the @smbmathbiology.bsky.social Canadian giants! Mark Lewis “One equation helps solve three paradoxes in the spatial ecology of predators and prey” Mark also wins the prestigious Akira Okubo Prize!! #SMB2025

Next up is former student & friend @stroblmar.bsky.social presenting new work with @cancerconnector.bsky.social on “Bridging the gap: What preclinical experiments can teach us about cancer drug scheduling” #MathOnco #SMB2025

Over a month ago a bunch of #MathOnco and #AIOnco researchers got together in Syracuse to discuss how #AI may and may not change the field. Here are some thoughts in a collective effort led by @rrockne.bsky.social:

The Future of Mathematical Oncology in the Age of AI

mathematical-oncology.org

mathematical-oncology.org

Emerging ‘co-scientist’ systems use teams of chatbots to mimic the deliberations of a research group. Do they really help? https://go.nature.com/4l3Lzbz

What’s it like to work with an AI team of virtual scientists?

Emerging ‘co-scientist’ systems use teams of chatbots to mimic the deliberations of a research group. Do they really help?

go.nature.com

Attending a conference entitled, The Future of Cancer Research: Unleashing the Power of Machine Learning, taking place in the historic city of Syracuse. Organized by @cityofhope.bsky.social @sergiobranciamore.bsky.social, Andrei Rodin, Konstancja Urbaniak and @rrockne.bsky.social

genomebiology.biomedcentral.com/articles/10.... Quite an indictment of some of the current single cell "virtual cell" foundation models. Even for the relatively mundane applications, cell labeling, batch correction etc, they are poor compared to much simpler & cheaper methods.

Zero-shot evaluation reveals limitations of single-cell foundation models - Genome Biology

Foundation models such as scGPT and Geneformer have not been rigorously evaluated in a setting where they are used without any further training (i.e., zero-shot). Understanding the performance of mode...

genomebiology.biomedcentral.com

What is the difference between PINNs, Universal PINNs, Neural Differential Equations (DEs) and Universal DEs? Don’t miss this blog post that I wrote with a bunch of amazing colleagues from a #MechanisticLearning workshop in Canada mathematical-oncology.org/blog/learnin... @ocbe.bsky.social

Learning Dynamics with Neural Networks

mathematical-oncology.org

mathematical-oncology.org