How do brain areas control each other? 🧠🎛️ ✨In our NeurIPS 2025 Spotlight paper, we introduce a data-driven framework to answer this question using deep learning, nonlinear control, and differential geometry.🧵⬇️
Sarthak Chandra
@sarthakc.bsky.social
Interested in neuroscience, development and dynamical systems | Faculty member @ ICTS | Previously: @MIT, @UMD, @IITK
Our next paper on comparing dynamical systems (with special interest to artificial and biological neural networks) is out!! Joint work with @annhuang42.bsky.social , as well as @satpreetsingh.bsky.social , @leokoz8.bsky.social , Ila Fiete, and @kanakarajanphd.bsky.social : arxiv.org/pdf/2510.25943
Two cool papers out in Neuron today on memory. 1. Animals can be trained to activate specific remote memories at will: www.cell.com/neuron/fullt... 2. Interactions between cortex and amygdala during reactivation in NREM sleep help enhance perceptual memories: www.cell.com/neuron/fullt... 🧠📈 🧪
Closed-loop modulation of remote hippocampal representations with neurofeedback
Animal models of memory retrieval trigger retrieval with cues and measure retrieval using behavior. Coulter et al. developed a neurofeedback paradigm that rewards hippocampal activity patterns associa...
cell.com
1/ Our paper appeared in @Nature today! www.nature.com/articles/s41... w/ Fiete Lab and @khonamikail.bsky.social . Explains emergence of multiple grid cell modules, w/ excellent match to data! Novel mechanism for applying across vast systems from development to ecosystems. 🧵👇
Global modules robustly emerge from local interactions and smooth gradients - Nature
The principle of peak selection is described, by which local interactions and smooth gradients drive self-organization of discrete global modules.
nature.com
1/ Super-excited to share our new work “Episodic and associative memory from spatial scaffolds in the hippocampus”, that just appeared in Nature! www.nature.com/articles/s41... Key insights and ideas 👇#tweeprint
Episodic and associative memory from spatial scaffolds in the hippocampus - Nature
A neocortical–entorhinal–hippocampal network model based on grid cell states recapitulates experimental results and reconciles the spatial, associative and episodic memory roles of the hippocampus.
nature.com