Sazanov Lab

@sazanovlab.bsky.social

Professor, Institute of Science and Technology Austria Visiting Professor, Imperial College London Structure/function of molecular machines and membrane proteins cryoEM Bioenergetics Fellow of Royal Society and EMBO

Authors use an elegant transgenic model to demonstrate that acute oral administration of metformin targets mitochondrial complex I to lower blood glucose. A crucial contribution to the debate about the mechanisms of action of #metformin. #metabolism #glucose doi.org/10.1126/scia...

Metformin targets mitochondrial complex I to lower blood glucose levels

Acute oral metformin administration lowers blood glucose levels by targeting mitochondrial complex I.

doi.org

Árbol del Tule, Montezuma cypress near Oaxaca in Mexico is amazing. It is the biggest tree in the world by trunk width (14 m diameter). How just a few green needles maintain this tree over 2000 years is a mystery to me.

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Interested in a doing a PhD at Institute of Science and Technology Austria (ISTA)? Exciting research in phys, chem, structural biology, math, neuro, earth sciences, computer sciences and more... Sign up here for the virtual student open day Nov 20, 2024. phd.pages.ista.ac.at/student-open...

Virtual Student Open Day 2024

Each year, the Institute of Science and Technology Austria (ISTA) opens its doors to give prospective PhD and internship candidates an insight into what it is like to study and do research at the inst...

phd.pages.ista.ac.at