🍰Interested in reading more about the study? Here's the N&Vs article written by Joanna R. Kovalski & Davide Ruggero. 👉https://rdcu.be/ejwqJ bit.ly/4jnydWI

Breaking up translation condensates in cancer - Nature Cell Biology

Translational control is emerging as a key regulator of cancer. The RNA-binding protein PABPC1 is shown to drive chronic myeloid leukaemia (CML) by enhancing the translation of pro-oncogenic mRNAs thr...

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This article hits the nail on the head for the challenges being manufactured in US scientific research especially for those of us early career folks. America’s Brightest Minds Will Walk Away www.nytimes.com/2025/04/03/o...

Opinion | The Uncertain Fate of the Young American Scientist

Young researchers are choosing between staying in science and staying in the United States.

nytimes.com

Not just "housekeeping." Targeting RNA translation is a specific vulnerability of prostate cancer cells. Exciting to see what's next on the horizon for small molecule RNA therapeutics.

UCSF@ucsanfrancisco.bsky.social · last yr.

Tumors overproduce the proteins that drive metabolism, cell division and more. A UCSF team has found that a breast cancer drug, zotatifin, jams the protein assembly line in prostate tumors – offering new hope for prostate cancer patients. tiny.ucsf.edu/665V7N

A powerful toolbox to study IRES-dependent selective translation of mRNAs. An important resource for the field! Excited to use these new tools to study a critical, yet under-appreciated mechanism of translational specificity. Congrats Barna and Leppek labs! #RNA t.co/LmbFyKIfhh

Stand Up For Science Rally Today at SF City Hall! Letting our voices be heard to keep hands off the NIH and keep pushing the bounds of human knowledge! 🔬🧪

We are grateful to @marasherman.bsky.social and Dr. Zainab Hussain for their insightful highlighting of our work out now in Nature Cell Biology.

Nature Cell Biology@natcellbio.nature.com · last yr.

🍰Interested in reading more about the study? Here is the N&Vs article written by Zainab Hussain & Mara H. Sherman. 👉🏽https://rdcu.be/ecb4q bit.ly/43ljpme

We are thrilled to share our discovery of a new factor, the RBP RBM42, which is key to fueling pancreas cancer through the deadly oncogene Myc. I look forward to what we uncover next! Thanks to the fantastic team lead by @DavideRuggero @rushika-perera.bsky.social & @genophoria.bsky.social!

Nature Cell Biology@natcellbio.nature.com · last yr.

☕️Kovalski et al. perform a genome-wide CRISPRi screen for selective MYC translation regulators and identify RBM42 as a ribosome-associated protein that modulates MYC translation and an #oncogenic mRNA program required for #PancreaticCancer growth. 👉🏼https://rdcu.be/ecb4e bit.ly/41FKwY3