Discovery looks different now. So does scripps.edu. 🔬🌟 Our redesigned website is faster, easier to navigate and built to bring you closer to the discoveries happening inside our labs. Find out where your curiosity takes you: https://www.scripps.edu/

The all-new scripps.edu is live!🎉 With simplified navigation, richer storytelling and more ways to connect, our redesigned website brings you closer to the science and people driving discovery. Take a look: https://www.scripps.edu/

This summer, Scripps Research welcomed a record number of interns, with more than 100 students joining labs across the institute. 🔬🌟 Through programs including REACH, SURF and SRTI internships, they gained hands-on research experience, mentorship, workshops and scientific seminars.

During the first weeks of pregnancy, individual placental cells merge, forming a barrier that ferries oxygen and nutrients to the fetus while keeping the mother’s immune system at bay. Scientists at Scripps Research identified galectin-3 as a key player in this transformation.

The Hazen Campus at Scripps Research has been an architectural landmark since 1995. The campus exemplifies a fusion of functional design and brilliance. Not just a structure but a ‘monastery for scientists,’ it is a testament to enduring architectural standards and a cradle for scientific discovery.

📣 Front Row lecture series resumes August 19! Each free lecture is offered virtually or in person at the Scripps Research Auditorium at 4:00 p.m. PT. Be sure to check out #ScienceinAction, an interactive showcase hosted by the speaker's lab. More: https://ow.ly/6Vgg50Zrxgh

At #ScienceInAction, the Erb lab showed how miniaturized, high-throughput screening helps scientists make and test thousands of chemical compounds in search of molecular glues, then use cell-based and genomic tools to identify compounds that may target cancers through new mechanisms.

The International Society for the Study of the Origin of Life - The International Astrobiology Society has awarded Prof. Ramanarayanan Krishnamurthy the Aleksandr Ivanovich Oparin Medal for “best sustained scientific research in the origin of life field.” More: https://ow.ly/JM7l50ZruvP

Congrats to Phil Baran, recipient of the 2026 Mitsui Chemicals Catalysis Science Award for pioneering catalytic radical cross-coupling methods that enable efficient construction of complex molecules using abundant metals and readily available starting materials. More: https://ow.ly/K0Hj50ZqRIY

John Diekman funds and builds next-generation life sciences companies, while Sue Diekman lends her expertise to several nonprofits. Though their charitable interests are diverse, the couple always takes a hands-on approach to giving. More: https://ow.ly/6LNh50ZnsMZ

@scripps.edu PhD candidate Dom Haas received the @societymucosalimm.bsky.social Young Investigator Award to present his work at #ICMI2026 👏

M. Reza Ghadiri has spent decades asking how life’s complexity can arise from basic chemical building blocks. But behind the theories is a story that begins earlier—inside a childhood bedroom filled with improvised experiments, stained walls and the smell of sulfur. More: https://ow.ly/JnjW50ZnszF

Antibiotic use in early life impairs #MAIT cell–mediated immunity in adulthood. From LeBlanc, Sobel, @mikerobe.bsky.social and colleagues @scripps.edu: rupress.org/jem/article/... 📘 Part of our #Mucosal #Immunology collection: 👉 rupress.org/jem/collecti... #ICMI2026

Grants to help Scripps Research expand life-saving wastewater program

Grants to help Scripps Research expand life-saving wastewater program

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New #HIV vaccine shows unprecedented success in preclinical study bit.ly/4fjL1Oi Scientists at La Jolla Institute for Immunology, @scripps.edu, and IAVI show that vaccine approach yields high numbers of HIV-neutralizing antibodies in non-human primates — published in @nature.com #health #medicine

New HIV vaccine shows unprecedented success in preclinical study

Vaccine approach yields high numbers of HIV-neutralizing antibodies in non-human primates

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"For years, HIV has resisted traditional vaccine strategies... "A team led by scientists at La Jolla Institute for Immunology (LJI) and Scripps Research now reports a potential breakthrough..." bit.ly/3QKjwEl #Health #Medicine #HIV #VaccineResearch #Viruses #Immunology #Antibodies #ImmuneSystem

Germline‑Targeting HIV Vaccine Generates Broadly Neutralizing Antibodies in Primates

To test this strategy, the team engineered protein immunogens that mimic key HIV envelope structures known to initiate bnAb development.

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Back-to-back studies from Scripps Research in Science Magazine and Nature reveal a faster, cleaner way for chemists to build complex, 3D molecules, including shapes once considered impossible to assemble using straightforward radical methods.

Cross-coupling, radically simplified - Scripps Research Magazine

A new reaction developed by the Baran lab transforms simple building blocks into complex molecules with the clean release of nitrogen.

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Germline-targeting sequential immunization generated functional bnAbs in serum that neutralized many HIV strains in lab tests. Published in Nature with the La Jolla Institute for Immunology (LJI), Emory University, IAVI and others, the study shows the vaccine strategy can guide antibody evolution.

Scripps Research scientists train the immune system to make antibodies against numerous HIV strains

LA JOLLA, CA—HIV is globally so diverse, consisting of hundreds of thousands of different strains, that antibodies capable of blocking one strain may not recognize another. This strain variability has been one of the greatest barriers to developing a vaccine that can provide broad protection against…

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We’re excited to welcome Joan Pulupa to Scripps Research as an assistant professor! Using smell-sensing neurons and advanced microscopy, including MINFLUX, Pulupa’s lab will explore how genome organization shapes brain cells and what it may reveal about neurodegenerative conditions.

Joan Pulupa joins Scripps Research faculty to study the organization of DNA in brain cells and its links to neurodegeneration

Using smell-sensing neurons and advanced microscopy, Pulupa’s lab will explore how genome organization affects brain cells, and what it may reveal about neurodegenerative conditions.

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Growing up in rural Littlerock, CA, Alexandra Salazar didn’t picture herself becoming a scientist. Today, she's studying in the Lander Lab, developing new cryo-EM approaches to visualize proteins inside mitochondria and better understand disease. More: https://ow.ly/rfx750Zc1W2

Scripps Research scientists Kristian G. Andersen, Josh Levy and Karthik Gangavarapu have received two new grants from the Gates Foundation totaling $2M to advance global disease surveillance by expanding wastewater surveillance and developing AI systems to improve outbreak prediction.

Scripps Research scientists awarded $2M to advance global disease surveillance

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President of the Scripps Research Computational Biology & Bioinformatics affinity group and graduate student Ian Newman spoke with participants in our inaugural AI Hackathon, hosted with Amazon Web Services (AWS), where researchers explored agentic AI and cloud computing. 🔗 https://ow.ly/YV3W50ZiSaF

More than 100 scientists affiliated with Scripps Research were recognized in Research.com’s 2026 Best Scientists rankings across immunology, biology and biochemistry, chemistry, medicine and more. �� https://ow.ly/urwL50ZfYfYBi

Postdoctoral fellow Júlia Castro has been named to the 2026 class of Pew Latin American Fellows Program in the Biomedical Sciences! A member of Renan V. H. de Carvalho, Ph.D.'s lab, she's among 10 fellows receiving funding from The Pew Trusts to study the immune system. 🔗 https://ow.ly/9vJE50ZfXV3

The first high-resolution structures of human Argonaute 2 in its cutting-ready state, reported in Nature Structural & Molecular Biology, reveal how this RNA interference protein cuts its targets while providing a blueprint for designing more effective siRNA therapeutics.

Molecular scissors caught in action: A structural blueprint for RNA therapeutics

A Scripps Research team has captured the first high-resolution structural images of human Argonaute 2 in its cutting-ready state, revealing why some small interfering RNA (siRNA) molecules work better than others and how to design more effective ones for this emerging therapy.

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As antibiotic resistance continues to threaten global health, Scripps Research scientists discovered that disabling the bacterial protein SagA restores vancomycin’s power against vancomycin-resistant Enterococcus faecium (VREfm), according to a new Nature Communications study.

Back in action: Researchers make drug-resistant bacteria vulnerable again

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Blocking the receptor for the inflammatory signaling molecule IL-6 reduced alcohol consumption in alcohol-dependent preclinical models, according to a new Scripps Research study. The findings implicate neuroimmune signaling in alcohol use disorder.

Immune molecule may drive excessive drinking in alcohol use disorder

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Congratulations to Júlia Castro, postdoc in the lab, and now a recipient of the PEW Latin America postdoctoral fellowship! Exciting science in the years ahead! www.pew.org/en/about/new...

Pew Supports 10 Leading Latin American Scientists

These 10 postdoctoral fellows from seven Latin American countries—Argentina, Brazil, Chile, Colombia, Mexico, Peru, and Uruguay—will each receive two years of funding to conduct research in laboratori...

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Scripps Research, in collaboration with UC San Diego and the Lowy Medical Research Institute, found in a new Nature Neuroscience study that while erucamide levels drop as photoreceptors begin to die, restoring the molecule activates cellular responses that support retinal stability.

Newly identified molecule strengthens the eye’s response to damage in retinal disease

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New lab studies explain how SAR’877, an experimental cancer therapy, works as it enters patient testing. Findings show the drug revives exhausted T cells more precisely than existing approaches without triggering the dangerous inflammation that has limited similar drugs in the past.

Lab studies explain how new cancer drug works as it enters patient testing

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